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N. W. BUNNETT, J. R. REEVE, R. DIMALINE, J. E. SHIVELY, D. HAWKE, J. H. WALSH, The Isolation and Sequence Analysis of Vasoactive Intestinal Peptide from a Ganglioneuroblastoma, The Journal of Clinical Endocrinology & Metabolism, Volume 59, Issue 6, 1 December 1984, Pages 1133–1137, https://doi.org/10.1210/jcem-59-6-1133
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Abstract
A ganglioneuroblastoma was excised at surgery from a 1-yr-old girl with severe watery diarrhea. The tumor, weighing 1 g, was extracted in trifluoracetic acid and contained 8.3 nmol immunoreactive vasoactive intestinal peptide. The peptide was isolated by affinity chromatography and high pressure liquid chromatography and was found to be identical to porcine vasoactive intestinal peptide by amino acid analysis and microsequence analysis.