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Jack Fishman, Robert M. Boyar, Leon Hellman, INFLUENCE OF BODY WEIGHT ON ESTRADIOL METABOLISM IN YOUNG WOMEN, The Journal of Clinical Endocrinology & Metabolism, Volume 41, Issue 5, 1 November 1975, Pages 989–991, https://doi.org/10.1210/jcem-41-5-989
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Abstract
The metabolism of estradiol in girls with anorexia nervosa was compared with obese subjects and normal weight, age and sex matched controls. Increasing body weight was accompanied by a sharp decrease in 2-hydroxylation of estradiol and an increase in 16α-hydroxylation. These metabolic changes are discussed in terms of the biological activity of 2-hydroxyestrone and estriol.
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Copyright © 1975 by The Endocrine Society
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