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S. S. C. Yen, R. Rebar, G. VadenBerg, F. Naftolin, Y. Ehara, S. Engblom, K. J. Ryan, K. Benirschke, J. Rivier, M. Amoss, R. Guillemin, SYNTHETIC LUTEINIZING HORMONE-RELEASING FACTOR: A potent stimulator of gonadotropin release in man, The Journal of Clinical Endocrinology & Metabolism, Volume 34, Issue 6, 1 June 1972, Pages 1108–1111, https://doi.org/10.1210/jcem-34-6-1108
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Abstract
Synthetic LRF (single IV 150 μg dose) elicited a prompt increase in circulating LH in all 7 male subjects tested. The mean maximal rise to greater than 8-fold basal levels was reached within 20–30 min. A concomitant but quantitatively smaller FSH release was observed. Variability in response between individuals was not related to body surface area or age.
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Copyright © 1972 by The Endocrine Society
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Rapid Communications
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