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HAROLD E. CARLSON, J. CHRISTIAN GILLIN, PHILLIP GORDEN, FREDERICK SNYDER, Absence of Sleep-Related Growth Hormone Peaks in Aged Normal Subjects and in Acromegaly, The Journal of Clinical Endocrinology & Metabolism, Volume 34, Issue 6, 1 June 1972, Pages 1102–1105, https://doi.org/10.1210/jcem-34-6-1102
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Abstract
Plasma growth hormone (GH) was measured during sleep in 12 normal volunteers of various ages and in 6 patients with acromegaly. Four of the 6 volunteers over 50 yr of age failed to show a sleep-peak of GH. The presence or absence of a GH sleep-peak in the normals was not consistently related to the occurrence of slow-wave sleep. None of the 6 acromegalics showed the usual GH peak early in sleep.
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Copyright © 1972 by The Endocrine Society
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