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W. D. ALEXANDER, D. G. MCLARTY, J. ROBERTSON, J. SHIMMINS, B. E. W. BROWNLIE, R. MCG. HARDEN, A. R. PATEL, Prediction of the Long-Term Results of Antithyroid Drug Therapy for Thyrotoxicosis, The Journal of Clinical Endocrinology & Metabolism, Volume 30, Issue 4, 1 April 1970, Pages 540–543, https://doi.org/10.1210/jcem-30-4-540
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Abstract
Ninety-three patients were studied during and for an average of 20 months after long-term carbimazole and triiodothyronine therapy. On the last day of antithyroid drug therapy 51 patients had thyroid uptakes suppressed into the normal range (20 min thyroid uptake below 8%), and of these 35 remained euthyroid and 16 relapsed. Forty-two patients did not show suppression of uptake and of these 10 remained euthyroid and 32 relapsed. Prediction of the outcome after 6 months' treatment was no less reliable than on the last day of antithyroid drug therapy. Prediction after 3 months' treatment was unsatisfactory.