Abstract

Fourteen subjects with Turner's syndrome were studied before and after insulin hypoglycemia: 11 had brisk growth hormone responses as measured by radioimmunoassay and 3 had limited responses with maximum values below 10 mμg/ml. Twelve healthy female control subjects of normal stature were studied in the same manner and 11 had brisk responses, with one showing a limited response. No one in either group had complete absence of growth hormone. Thus, some defect other than growth hormone deficit must be implicated in the short stature of patients with Turner's syndrome.

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