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VINCENT J. PILEGGI, HOWARD A. SEGAL, ORVILLE J. GOLUB, Determination of Organic Iodine Compounds in Serum. III. Iodotyrosines in Normal Human Serum, The Journal of Clinical Endocrinology & Metabolism, Volume 24, Issue 3, 1 March 1964, Pages 273–280, https://doi.org/10.1210/jcem-24-3-273
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Column chromatographic fractionation of the 127I compounds of normal human serum and plasma has failed to reveal detectable amounts of the thyroxine precursors monoiodotyrosine (MIT) and diiodotyrosine (DIT). Over 90 % of the serum proteinbound iodine appeared in the iodothyronine fraction. The detection of iodotyrosine-iodine at levels as low as 0.2 μg/100 ml serum is possible with the method described.
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Copyright © 1964 by The Endocrine Society
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