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ROBERT F. SKEELS, THE REVERSIBILITY OF OSTEOPOROSIS IN CUSHING’S DISEASE: CASE REPORT, The Journal of Clinical Endocrinology & Metabolism, Volume 18, Issue 1, 1 January 1958, Pages 61–64, https://doi.org/10.1210/jcem-18-1-61
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The reversible nature of osteoporosis is generally accepted, but it is not often possible to demonstrate striking roentgenographic evidence of healing. A case of advanced Cushing’s disease in an 11-year-old girl is presented. Osteoporosis with multiple fractures was a major cause of disability. Bilateral subtotal adrenalectomy was performed in two stages; x-ray treatment of the pituitary was given shortly after the first operation. Four years later there was remarkable x-ray evidence of the reversibility of the osteoporosis.