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D. EMERICK SZILAGYI, JOHN L. BARRETT, LUTHER E. PREUSS, THE AMOUNT OF TISSUE TO BE PRESERVED AT SUBTOTAL THYROIDECTOMY: AN ESTIMATE BASED ON SERIAL ISOTOPE TRACER MEASUREMENTS, The Journal of Clinical Endocrinology & Metabolism, Volume 15, Issue 11, 1 November 1955, Pages 1409–1421, https://doi.org/10.1210/jcem-15-11-1409
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Abstract
IDEALLY, the optimum amount of thyroid parenchyma to be preserved at thyroidectomy for an overfunctioning thyroid gland is that amount which will assure a euthyroid postoperative state and at the same time reduce to a minimum the danger of recurrent hyperthyroidism. Generally speaking, this is the smallest quantity of tissue compatible with euthyroidism, since, other factors being equal, the smaller the tissue remnant the less the probability of recurrence.
There are serious and obvious difficulties in the way of determining the exact dimensions of such an optimal parenchymal remnant in the traditional clinical manner. In a purely clinical method of estimation, the size of the remnant would be judged on the basis of the visual impression of the surgeon, and this intelligent guess would then be correlated with the clinical course of the disease. Visual impressions are deceptive, and their correlation with clinical manifestations, the assessment of which is likewise often a matter of subjective judgment, will not yield precise data.
