Volume 17, Issue 7, November 2017
Editorial
Editorial: Where is scientific publishing heading?
Retrospective
55 years together—our life with yeasts
Minireviews
Factors extending the chronological lifespan of yeast: Ecl1 family genes
Transporter engineering in biomass utilization by yeast
The focus in this review is engineering of transporters involved in sugar input and product output from yeast cell factories for improving bioproduction along with biomass utilization and metabolic pathways.
Systems biotechnology for protein production in Pichia pastoris
Systems biotechnology enables to understand and improve recombinant protein production in the methylotrophic yeast Pichia pastoris.
Lighting up yeast cell factories by transcription factor-based biosensors
Engineering Saccharomyces cerevisiae for high-level synthesis of fatty acids and derived products
This minireview focuses on recent advances in the production of fatty acids and fatty acid derivatives in the yeast Saccharomyces cerevisiae.
Research Articles
mRNA-Seq reveals accumulation followed by reduction of small nuclear and nucleolar RNAs in yeast exposed to antiviral ribavirin
This study found that antiviral ribavirin affected small non-coding RNAs in yeast, which may be significant when considering side effects in humans who are treated for viral infections by ribavirin.
First report of urease activity in the novel systemic fungal pathogen Emergomyces africanus: a comparison with the neurotrope Cryptococcus neoformans
In this study the authors confirmed, characterized and quantified urease activity of the novel systemic fungal pathogen, Emergomyces africanus.
Production of 3-geranyl-4-hydroxybenzoate acid in yeast, an important intermediate of shikonin biosynthesis pathway
Establishing a yeast strain for producing an important intermediate of shikonins, which are natural red naphthoquinone pigments and possess extensive pharmaceutical properties.
Differences in the arrangement of the Pdr5p multidrug transporter binding pocket of Saccharomyces cerevisiae and Kluyveromyces lactis
Using our diS-C3(3) diagnostic assay, we show that the ability of common substrates (azoles) of ScPdr5p and KlPdr5p to competitively inhibit the Pdr5p-mediated efflux of the probe differs in the two species as a consequence of tighter arrangement of the KlPdr5p binding pocket compared to that of ScPdr5p.
Nanopore sequencing enables near-complete de novo assembly of Saccharomyces cerevisiae reference strain CEN.PK113-7D
Whole genome sequencing of Saccharomyces cerevisiae strain CEN.PK113–7D using nanopore technology sequencing yielded a near complete reference genome with 770 Kbp of undisclosed novel genetic information.
Urea production by yeasts other than Saccharomyces in food fermentation
Using Chinese liquor fermentation as model system for spontaneous food fermentation, a correlation was found between the presence of newly-identified urea-producing yeasts and the concentration of urea in the final product.