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Bacterial Toxins

Teresa Frisan, Peter Sebo

in Thematic Issues

In spite of many years of research on bacterial toxins, this field still offers surprising discoveries, such as identification of new toxins, or novel biological facets of already identified effectors, thus contributing to elucidate better the complexity of the host-microbe interaction. The mini-reviews and the original papers presented in this thematic issue show that the field of bacterial toxins is more alive than ever and many years of exciting research await in front of us.

Thematic Issue

Editorial: Why still study bacterial toxins in the third millennium?

Teresa Frisan, Peter Sebo

Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme

Jiri Masin, Radim Osicka, Ladislav Bumba, Peter Sebo

Bacterial protein toxins in human cancers

Francesca Rosadi, Carla Fiorentini, Alessia Fabbri

Transmembrane segments of complement receptor 3 do not participate in cytotoxic activities but determine receptor structure required for action of Bordetella adenylate cyclase toxin

Tomas Wald, Adriana Osickova, Jiri Masin, Petra Matyska Liskova, Inga Petry-Podgorska, Tomas Matousek, Peter Sebo, Radim Osicka

Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells

Linn Kymre, Roger Simm, Tore Skotland, Kirsten Sandvig

From GFP to β-lactamase: advancing intact cell imaging for toxins and effectors

Madison Zuverink, Joseph T. Barbieri

A novel experimental platform for toxigenic and non-toxigenic Corynebacterium ulcerans infection in mice

Yu Mochizuki, Honami Saeki, Masaaki Iwaki, Hitrotaka Takagi, Keigo Shibayama, Hiromi Amao, Akihiko Yamamoto

Defective mutations within the translocation domain of Clostridium difficile toxin B impair disease pathogenesis

Therwa Hamza, Zhifen Zhang, Roman A. Melnyk, Hanping Feng

A tribute to Sjur: Sjur Olsnes, 1939-2014

R. John Collier

Bacterial nucleators: actin' on actin

Joana N. Bugalhao, Luis Jaime Mota, Irina S. Franco

Rho-modifying bacterial protein toxins

Klaus Aktories

Ultrasensitive detection of protease activity of anthrax and botulinum toxins by a new PCR-based assay

Alexander V. Kolesnikov, Arina V. Kozyr, Alyona K. Ryabko, Igor G. Shemyakin

Conformational plasticity is crucial for C3-RhoA complex formation by ARTT-loop

Hideaki Tsuge, Toru Yoshida, Toshiharu Tsurumura

The pattern of growth observed for Clostridium botulinum type A1 strain ATCC 19397 is influenced by nutritional status and quorum sensing: a modelling perspective

Adaoha E. C. Ihekwaba, Ivan Mura, Michael W. Peck, G. C. Barker

Inhibiting bacterial toxins by channel blockage

Sergey M. Bezrukov, Ekaterina M. Nestorovich

Masaaki Iwaki, Toshifumi Konda

Masaaki Iwaki, Toshifumi Konda

MARTX toxins as effector delivery platforms

Hannah E. Gavin, Karla J. F. Satchell

The chromosomal nature of LT-II enterotoxins solved: a lambdoid prophage encodes both LT-II and one of two novel pertussis toxin-like toxin family members in type II enterotoxigenic Escherichia coli (ETEC)

Michael G. Jobling

Editor's Choice

tRNAs taking charge

Jonathan W. Cruz, Nancy A. Woychik