Prevention of cardiovascular disease: does ‘every step counts’ apply for occupational work? Martin Halle 1,2* and Melanie Heitkamp 1 1 Department of Prevention and Sports Medicine, University Hospital Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; and 2 DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany Corresponding author. Department of Prevention and Sports Medicine, Accredited Centre for Sports Cardiology/EAPC, School of Medicine, University hospital ‘Klinikum rechts der Isar’, Technical University of Munich, Georg-Brauchle-Ring 56, D-80992 Munich, Germany. Tel: +49 89 289 24431, Email: [email protected] Graphical Abstract Leisure time physical activity and occupational physical activity in relation to major adverse cardiovascular events (MACE) and all-cause mortality (ACM). Cox regression models were adjusted for age, sex, body mass index, smoking, years in school, diabetes, systolic blood pressure, blood pressure medication, dietary preferences, alcohol consumption, chronic obstructive pulmonary disease by Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage, LDL cholesterol, HDL cholesterol and triglycerides, resting heart rate, vital exhaustion score, occupation, cohabitation, marital status, and household income.1 The potential role of preventive factors of leisure activity and negative factors increasing risk. HR, hazard ratio.