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Keywords: vascular diseases
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Journal Article
Characterizing the cardiovascular phenotype of a new zebrafish model of Marfan syndrome
P Y Sips and others
European Heart Journal, Volume 42, Issue Supplement_1, October 2021, ehab724.3379, https://doi.org/10.1093/eurheartj/ehab724.3379
Published: 14 October 2021
... of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Basic Science Vascular Diseases 3379 Characterizing the cardiovascular phenotype of a new zebra sh model of Marfan syndrome P.Y. Sips1...
Journal Article
MMP-2 gene silencing attenuates age-dependent carotid stiffness via reduction of elastin degradation and increased eNOS activation
Y M Puspitasari and others
European Heart Journal, Volume 42, Issue Supplement_1, October 2021, ehab724.3378, https://doi.org/10.1093/eurheartj/ehab724.3378
Published: 14 October 2021
...Y M Puspitasari; C Diaz-Canestro; L Liberale; T J Guzik; A J Flammer; N R Bonetti; S Constantino; F Paneni; A Akhmedov; J H Beer; F Ruschitzka; M Hermann; T F Luscher; I Sudano; G G Camici 3378 Basic Science Vascular Diseases MMP-2 gene silencing attenuates age-dependent carotid stiffness via...
Journal Article
The role of matrix metalloproteinase-2 on age-dependent arterial stiffness
Y.M Puspitasari and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3778, https://doi.org/10.1093/ehjci/ehaa946.3778
Published: 25 November 2020
... Heart House Basic Science - Vascular Diseases Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: [email protected]. 2020 This article is published and distributed under the terms of the Oxford University...
Journal Article
CD40 levels in plasma are associated with cardiovascular disease and in carotid plaques with a vulnerable plaque phenotype and remodelling
A Shami and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3782, https://doi.org/10.1093/ehjci/ehaa946.3782
Published: 25 November 2020
...A Shami; A Edsfeldt; A.C Shore; A Natali; F Khan; J Nilsson; E Lutgens; I Goncalves 3782 Basic Science Vascular Diseases: Biomarkers CD40 levels in plasma are associated with cardiovascular disease and in carotid plaques with a vulnerable plaque phenotype and remodelling A. Shami1, A. Edsfeldt2...
Journal Article
Modification of histone 3 lysine 27 (H3K27) trimethylation in EZH2 and JMJD3 deficient T cells attenuates atherosclerosis through polarization towards anti-inflammatory phenotypes
M Lacy and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3829, https://doi.org/10.1093/ehjci/ehaa946.3829
Published: 25 November 2020
... may be a promising candidate for further investigation to treat atherosclerosis. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): German Research Foundation (DFG) Basic Science - Vascular Diseases: Leukocytes, Inflammation, Immunity...
Journal Article
Murine transfer of a human gene variant associated with exceptional longevity displays senolytic effects both in immune compartment and endothelium of aged mice
E Ciaglia and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3830, https://doi.org/10.1093/ehjci/ehaa946.3830
Published: 25 November 2020
... and CV Basic Science - Vascular Diseases: Leukocytes, Inflammation, Immunity 3830 Basic Science Vascular Diseases: Leukocytes, In ammation, Immunity Murine transfer of a human gene variant associated with exceptional longevity displays senolytic effects both in immune compartment and endothelium...
Journal Article
Empagliflozin impairs smooth muscle cell proliferation, accelerates endothelial regeneration, and prevents neointima formation by altered expression of the vasoactive peptide apelin
J Dutzmann and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3837, https://doi.org/10.1093/ehjci/ehaa946.3837
Published: 25 November 2020
...J Dutzmann; L.M Bode; L Korte; K Kalies; S Koch; J Tongers; J Bauersachs; D.G Sedding Basic Science Vascular Diseases: Drugs, Drug Targets 3837 Empagli ozin impairs smooth muscle cell proliferation, accelerates endothelial regeneration, and prevents neointima formation by altered expression...
Journal Article
SIRT5 deficiency enhances the proliferative and therapeutic capacities of adipose-derived mesenchymal stem cell via metabolic switching
T Ou and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3840, https://doi.org/10.1093/ehjci/ehaa946.3840
Published: 25 November 2020
... budget only. Main funding source(s): Major Research Plan of the National Natural Science Foundation of China. National Science Fund for Distinguished Young Scholars. Basic Science - Vascular Diseases: Gene Therapy, Cell Therapy 3840 Basic Science Vascular Diseases: Gene Therapy, Cell Therapy SIRT5 de...
Journal Article
Methotrexate associated with a lipid core nanoparticle prevented the dilation and dissection of the aortic arch in mice with Marfan syndrome
M.C Guido and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3777, https://doi.org/10.1093/ehjci/ehaa946.3777
Published: 25 November 2020
... and dissection in the aortic arch, the hallmarks of MFS, in this animal model. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): FAPESP (Fundação de Amparo à Pesquisa do Estado de São Paulo) Basic Science - Vascular Diseases Basic Science...
Journal Article
Treating ApoE−/− mice with Toll-like receptor 7 ligand lead to expansion of marginal zone B cells, reduced plasma cholesterol and decreased atherosclerosis
G Paulsson-Berne and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3832, https://doi.org/10.1093/ehjci/ehaa946.3832
Published: 25 November 2020
...G Paulsson-Berne; G Karadimou; A Gistera; A Gallina; M Centa; M Salagianni; E Andreakos; G.K Hansson; S Malin; P Olofsson Basic Science - Vascular Diseases: Leukocytes, Inflammation, Immunity Abstract Background The interplay between innate and adaptive immunity is involved in the cause...
Journal Article
IgG1 antibodies against phosphorylcholine are associated with protection in SLE and atherosclerosis: potential underlying mechanisms
J Frostegard and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3833, https://doi.org/10.1093/ehjci/ehaa946.3833
Published: 25 November 2020
... clearance of dead cells. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): Swedish Heart and Lung Foundation, Reumatikerfonden Basic Science - Vascular Diseases: Leukocytes, Inflammation, Immunity Basic Science Vascular Diseases: Leukocytes...
Journal Article
Ponatinib induces vascular toxicity through the Notch-1 signaling pathway
R Madonna and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3838, https://doi.org/10.1093/ehjci/ehaa946.3838
Published: 25 November 2020
... Funding Acknowledgement Type of funding source: None Basic Science - Vascular Diseases: Drugs, Drug Targets 3838 Basic Science Vascular Diseases: Drugs, Drug Targets Ponatinib induces vascular toxicity through the Notch-1 signaling pathway R. Madonna1, D. Pieragostino2, M. Cufaro2, V. Doria2, P. Del...
Journal Article
Inhibition of BMP9 and BMP10 signalling by the ALK1-Fc Ligand Trap enhances systemic inflammation and increases vein graft atherosclerosis
A De Jong and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3828, https://doi.org/10.1093/ehjci/ehaa946.3828
Published: 25 November 2020
... - Vascular Diseases: Leukocytes, Inflammation, Immunity 3828 Basic Science Vascular Diseases: Leukocytes, In ammation, Immunity Inhibition of BMP9 and BMP10 signalling by the ALK1-Fc Ligand Trap enhances systemic in ammation and increases vein graft atherosclerosis A. De Jong, V.Q. Sier, H.A.B. Peters, J.W...
Journal Article
An increase in activated NKT-CD8+ cells is associated with the presence of hypoechoic carotid plaques
V Genkel and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3831, https://doi.org/10.1093/ehjci/ehaa946.3831
Published: 25 November 2020
...+ cells over 46.5 cells/uL was a predictor of the presence of hypoechoic carotid plaques with sensitivity of 81.8% and specificity of 45.0% Figure 1 Funding Acknowledgement Type of funding source: None Basic Science - Vascular Diseases: Leukocytes, Inflammation, Immunity Basic Science...
Journal Article
Neutrophil extracellular traps induce MCP-1 release from endothelial cells at the plaque rupture site in acute myocardial infarction
A Ondracek and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3834, https://doi.org/10.1093/ehjci/ehaa946.3834
Published: 25 November 2020
...): Austrian Science Fund Basic Science - Vascular Diseases: Leukocytes, Inflammation, Immunity 3834 Basic Science Vascular Diseases: Leukocytes, In ammation, Immunity Neutrophil extracellular traps induce MCP-1 release from endothelial cells at the plaque rupture site in acute myocardial infarction...
Journal Article
Plasma extracellular vesicles modulate immune cell gene expression following myocardial infarction
N Akbar and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3835, https://doi.org/10.1093/ehjci/ehaa946.3835
Published: 25 November 2020
... Foundation Project Grant, Novo Nordisk Fonden the Tripartite Immunometabolism Consortium and Wellcome Institutional Strategic Support Fund (ISSF) Basic Science - Vascular Diseases: Leukocytes, Inflammation, Immunity Basic Science Vascular Diseases: Leukocytes, In ammation, Immunity 3835 Plasma...
Journal Article
Inhibition of adamts13: a novel therapy to treat mechanical circulatory support-induced acquired von willebrand syndrome
S.J Deconinck and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3836, https://doi.org/10.1093/ehjci/ehaa946.3836
Published: 25 November 2020
... Type of funding source: Foundation. Main funding source(s): Fund for Scientific Research Flanders Basic Science - Vascular Diseases: Drugs, Drug Targets 3836 Basic Science Vascular Diseases: Drugs, Drug Targets Inhibition of adamts13: a novel therapy to treat mechanical circulatory support-induced...
Journal Article
Intravenous transplantation of human muse cells improves blood perfusion in a mouse model of limb ischemia
Y Hori and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3839, https://doi.org/10.1093/ehjci/ehaa946.3839
Published: 25 November 2020
... be a novel, less invasive, cost-effective, and subsequently more effective treatment for CLI patients. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): Grant-in-Aid for Scientific Research (KAKENHI) Basic Science - Vascular Diseases: Gene...
Journal Article
Increased pulse wave velocity strongly related to age in apparently healthy people of high cardiovascular risk population
G Zemtsovskaja and others
European Heart Journal, Volume 41, Issue Supplement_2, November 2020, ehaa946.3783, https://doi.org/10.1093/ehjci/ehaa946.3783
Published: 25 November 2020
... Science - Vascular Diseases: Biomarkers Basic Science Vascular Diseases: Biomarkers 3783 Increased pulse wave velocity strongly related to age in apparently healthy people of high cardiovascular risk population G. Zemtsovskaja1, K. Pilt2, J. Abina2, K. Meigas2, M. Viigimaa1 1North Estonia Medical Centre...
Journal Article
Current status of the management and outcomes of acute aortic dissection in Japan: Analyses of nationwide Japanese Registry of All Cardiac and Vascular Diseases-Diagnostic Procedure Combination data
Tetsuo Yamaguchi and others
European Heart Journal. Acute Cardiovascular Care, Volume 9, Issue 3_suppl, 1 October 2020, Pages S21–S31, https://doi.org/10.1177/2048872619872847
Published: 01 October 2020
... of the management and outcome of acute aortic dissection in Japan. Methods: A total of 18,348 patients with acute aortic dissection (type A: 10,131, type B: 8217) in the Japanese Registry of All Cardiac and Vascular Diseases database between April 2012–March 2015 were studied. Characteristics, clinical...