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Keywords: heart failure
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Journal Article
The role of sphingolipids in heart failure
Rana Hamouche and others
European Heart Journal Open, Volume 5, Issue 3, May 2025, oeaf035, https://doi.org/10.1093/ehjopen/oeaf035
Published: 02 May 2025
... Access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Advanced heart failure (HF...
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Development and External Validation of a Prediction Model for Prolonged ICU Stay in Heart Failure Patients
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Erming Yang and others
European Journal of Cardiovascular Nursing, zvaf075, https://doi.org/10.1093/eurjcn/zvaf075
Published: 28 April 2025
... Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Aim Prolonged ICU stays in heart failure patients are associated with poor prognosis and result in high medical expenses. To develop and validate a predictive model for prolonged ICU stays in heart failure patients...
Journal Article
Optimizing outcomes in heart transplantation: multidisciplinary Heart Teams and mechanical circulatory support for primary graft dysfunction
Assad Haneya and others
European Heart Journal Supplements, Volume 27, Issue Supplement_4, April 2025, Pages iv55–iv61, https://doi.org/10.1093/eurheartjsupp/suaf003
Published: 28 April 2025
... journals.permissions@oup.com. Abstract Heart transplantation (HTx) is a definitive treatment for selected patients with advanced heart failure. However, primary graft dysfunction (PGD), a severe early complication, is a major cause of post-HTx morbidity and mortality. This paper explores the pathophysiology...
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The intersection of obesity and acute heart failure: Cardiac structure and function and congestion across BMI categories
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Sofie Bøgh-Sørensen and others
European Heart Journal. Acute Cardiovascular Care, zuaf067, https://doi.org/10.1093/ehjacc/zuaf067
Published: 28 April 2025
... risk factors for heart failure (HF), however, the pathophysiologic consequences of obesity in patients with acute HF (AHF) are incompletely understood. Methods We examined cardiac structure and function, and congestion-related markers in adults hospitalized for AHF across 3 body mass index (BMI...
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Pulsed Field Ablation of Refractory Alternating Atrial Fibrillation and Atrial Flutter Using Impella CP in a Patient with Cardiogenic Shock: A Case Report
Isabel Rattka and others
European Heart Journal - Case Reports, ytaf216, https://doi.org/10.1093/ehjcr/ytaf216
Published: 28 April 2025
.... Case Summary We present the case of a 79-year-old male with ischemic cardiomyopathy and advanced heart failure, admitted with cardiogenic shock and regular narrow complex tachycardia. Initial attempts at electrical cardioversion combined with pharmacological rhythm control provided only temporary...
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Risk calculator of multimorbid risk of rehospitalisation and death from heart failure – including the contribution of the gut microbiome
Muhammad Zubair Israr and others
European Journal of Preventive Cardiology, zwaf270, https://doi.org/10.1093/eurjpc/zwaf270
Published: 28 April 2025
...—for further information please contact journals.permissions@oup.com. Abstract Background The elucidation of the contributory role of multimorbidity to heart failure (HF) including the gut-heart axis has added a new dimension to our understanding of HF pathophysiology which is not reflected in currently...
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Cardioprotective drugs and heart failure/cardiomyopathy incidence in chemotherapy-treated cancer survivors of breast cancer and non-Hodgkin lymphoma: A retrospective cohort study in England
Pooja Hindocha and others
European Heart Journal Open, oeaf039, https://doi.org/10.1093/ehjopen/oeaf039
Published: 25 April 2025
..., ACEis and/or beta-blockers in the year following cancer diagnosis and subsequent risk of heart failure/cardiomyopathy (HF/CM) in chemotherapy-treated breast cancer and Non-Hodgkin Lymphoma (NHL) survivors. Methods This cohort study used linked English electronic healthcare records from 9,875 adult...
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Effects of SGLT2 Inhibitors in Patients with Cancer and Diabetes Mellitus: A Systematic Review and Meta-analysis
Giuseppina Novo and others
European Heart Journal - Cardiovascular Pharmacotherapy, pvaf028, https://doi.org/10.1093/ehjcvp/pvaf028
Published: 25 April 2025
... by cancer therapies, which are known to have cardiotoxic effects. Sodium-glucose cotransporter 2 inhibitors (SGLT2i), initially developed for treating diabetes, have shown promising cardiovascular benefits in non-cancer populations, particularly in preventing heart failure (HF) and reducing HF-related...
Journal Article
Heart rate-lowering drugs and outcomes in hypertension and/or cardiovascular disease: a meta-analysis
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Elias Sanidas and others
European Heart Journal, ehaf291, https://doi.org/10.1093/eurheartj/ehaf291
Published: 25 April 2025
.... (baseline/attained HR: 76.2/65.6 b.p.m.). HR-lowering reduced coronary heart disease by 16%, heart failure by 9%, CV mortality by 14%, and all-cause mortality by 13% but increased adverse event-driven discontinuations by 25%. Significant mortality reductions were noted in post-acute myocardial infarction...
Journal Article
Natriuretic response prediction equation for use with oral diuretics in heart failure
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Juan B Ivey-Miranda and others
European Heart Journal, ehaf268, https://doi.org/10.1093/eurheartj/ehaf268
Published: 24 April 2025
... to assess oral diuretic response in outpatients with heart failure (HF). The natriuretic response prediction equation (NRPE) predicts natriuresis following a loop diuretic dose using a urine sample 2 h after the dose and was validated to accurately predict intravenous diuretic response. The primary aim...
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Identification of Anticancer Drugs Associated to Cancer Therapy-Related Cardiac Dysfunction: A VigiBase® Disproportionality Analysis
Damien Legallois and others
European Heart Journal - Cardiovascular Pharmacotherapy, pvaf027, https://doi.org/10.1093/ehjcvp/pvaf027
Published: 24 April 2025
.... It highlights discrepancies compared to drugs recommended for cardiac dysfunction evaluation in the 2022 ESC Guidelines. This underscores the importance of including CTRCD as a safety endpoint in cancer studies. Graphical Abstract Graphical Abstract heart failure cancer therapy-related cardiac dysfunction...
Journal Article
Study design and rationale of the AZIMUTH trial: a smartphone, app-based, E-health-integrated model of care for heart failure patients
Domenico D’Amario and others
European Heart Journal - Digital Health, ztaf040, https://doi.org/10.1093/ehjdh/ztaf040
Published: 24 April 2025
...—for further information please contact journals.permissions@oup.com. Abstract Aims Despite advancements in disease-modifying therapies, the rate of hospitalizations in patients with heart failure (HF) remains high, with an increased risk of future adverse events and healthcare costs. In this context...
Journal Article
Early initiation of SGLT2 inhibitors after acute myocardial infarction
Andeas Hammer and others
European Heart Journal - Cardiovascular Pharmacotherapy, pvaf020, https://doi.org/10.1093/ehjcvp/pvaf020
Published: 18 April 2025
... Heart failure Acute myocardial infarction Over the past decade, sodium-glucose cotransporter-2 (SGLT2) inhibitors have emerged as key agents providing cardiovascular, renal, and metabolic protection in chronic conditions. Recent evidence from a large Scandinavian cohort study indicates...
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Combined circulating microRNA and peptide biomarkers for prognostication in heart failure
Lee Lee Wong and others
Cardiovascular Research, cvaf065, https://doi.org/10.1093/cvr/cvaf065
Published: 17 April 2025
..., please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com. heart failure microRNA...
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Survival Benefit of Secondary Prevention Medical Therapy in Takotsubo Cardiomyopathy: A Bayesian Network Meta-Analysis
Daud Mutahar and others
European Heart Journal Open, oeaf040, https://doi.org/10.1093/ehjopen/oeaf040
Published: 16 April 2025
... patient cohort. Takotsubo cardiomyopathy heart failure pharmacotherapy acute coronary syndrome ACCEPTED MANUSCRIPT 1 Survival Benefit of Secondary Prevention Medical Therapy in Takotsubo 2 Cardiomyopathy: A Bayesian Network Meta-Analysis 3 4 Authors: Daud Mutahar1, Ammar Zaka2, Stephen Bacchi3, Brandon...
Journal Article
Obesity update: cardiovascular risk and therapeutic innovations (focus on semaglutide and tirzepatide)
Luca Antonio Felice Di Odoardo and others
European Heart Journal Supplements, Volume 27, Issue Supplement_3, March 2025, Pages iii137–iii142, https://doi.org/10.1093/eurheartjsupp/suaf032
Published: 16 April 2025
... of leading to a statistically significant reduction in the primary composite outcome of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in obese, non-diabetic patients with pre-existing cardiovascular disease. Furthermore, in the context of heart failure with preserved ejection...
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Evaluation of Seismocardiography in Detecting Preload Changes and Cardiovascular Disease: A Comparative Study with Transthoracic Echocardiography
Ahmad Agam and others
European Heart Journal - Digital Health, ztaf037, https://doi.org/10.1093/ehjdh/ztaf037
Published: 16 April 2025
... filling pressures. Graphical Abstract Graphical Abstract Heart failure seismocardiography echocardiography diastolic dysfunction preload ACCEPTED MANUSCRIPT 1 Evaluation of Seismocardiography in Detecting Preload Changes and 2 Cardiovascular Disease: A Comparative Study with Transthoracic 3...
Journal Article
MitraClip and repair surgery: comparable results?
Francesco Bianchini and others
European Heart Journal Supplements, Volume 27, Issue Supplement_3, March 2025, Pages iii36–iii39, https://doi.org/10.1093/eurheartjsupp/suaf013
Published: 16 April 2025
... regurgitation . Circulation 2001 ; 103 : 1759 – 1764 . 4 Goliasch G , Bartko PE , Pavo N , Neuhold S , Wurm R , Mascherbauer J et al Refining the prognostic impact of functional mitral regurgitation in chronic heart failure . Eur Heart J 2018 ; 39 : 39...
Journal Article
New nosologies: atriogenic valvular regurgitation
Federica Coletti and others
European Heart Journal Supplements, Volume 27, Issue Supplement_3, March 2025, Pages iii102–iii104, https://doi.org/10.1093/eurheartjsupp/suaf025
Published: 16 April 2025
... are predominant) and an atrial phenotype (when annulus dilatation and atrial remodelling are predominant). Both phenotypes are frequent in patients with heart failure and are associated with a significant increase in morbidity and mortality, representing a relevant therapeutic target. This work focuses...
Journal Article
The role of epicardial adipose tissue remodelling in heart failure with preserved ejection fraction
Carolina Janssen-Telders and others
Cardiovascular Research, cvaf056, https://doi.org/10.1093/cvr/cvaf056
Published: 16 April 2025
... compared obese HFpEF participants, non-obese HFpEF participants, and non-obese controls free of heart failure. Their findings revealed that all HFpEF groups exhibited LV dysfunction and elevated filling pressures, irrespective of BMI. However, obese HFpEF participants additionally presented with greater...