...-ECV independently predicts incident AF. Methods We studied 1,261 participants from the Multi-Ethnic Study of Atherosclerosis (MESA) free of AF at baseline who underwent myocardial T1-mapping between 2010–2012. Participants were followed prospectively for incident AF. Associations between ECV...

... angiography (CCTA) enables direct visualization and volumetric quantification of non-calcified plaque volume (NCPV), capturing a biologically active component of coronary atherosclerosis. No comprehensive synthesis of NCPV's prognostic significance, measurement reproducibility, and pharmacological...

... features and the lack of routine sterol quantification, diagnostic delays are common, leading to inappropriate dietary interventions that may paradoxically accelerate vascular damage. Case Summary We herein describe the case of a 13-year-old boy with sitosterolemia and early-onset atherosclerosis...

.../ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background and Aims While inflammation and (auto-)immunity are modifiers of atherosclerosis, immunological determinants of cardiovascular risk beyond the established...

.../standard-publication-reuse-rights ) Abstract Background and Aims To assess the prevalence of subclinical coronary atherosclerosis and its association with myocardial infarction, death or myocardial infarction, and clinically driven coronary revascularization in asymptomatic women and men in a Danish...

... pathways. Methods and results Our zebrafish functional screening of EC mechanoreceptors identified PKD1 and PKD2 as anti-apoptotic, protective factors in the zebrafish endothelium. In mice, we show that inducible EC-specific loss of PKD1, but not PKD2, led to increased atherosclerosis. To dissect...

... with prolonged exposure to risk factors. In contrast, imaging-based detection of subclinical atherosclerosis provides a more accurate assessment of cardiovascular risk by identifying established vascular disease. We aimed to develop and prospectively validate an artificial intelligence–based tool using retinal...

.... Inflammation Interleukin-6 Atherosclerosis Cardiovascular diseases Stress Physiological Ziltivekimab In 1936, Hans Selye reported that agents as different as cold, surgical injury, spinal shock, excessive exercise, and sublethal intoxication provoked one stereotyped reaction in the rat: Adrenocortical...

.... Graphical Abstract Graphical Abstract For image description, please refer to the figure legend and surrounding text. Arrhythmias Athletes Atrial fibrillation Coronary atherosclerosis Exercise-induced cardiac remodelling Myocardial fibrosis Sports cardiology E-Dekker #03-002-2023-0036...

... Atherosclerosis Cholesterol Mixed hyperlipidaemia siRNA Zodasiran Arrowhead Pharmaceuticals 10.13039/100014931 Mixed hyperlipidaemia is a heterogeneous disorder characterized by elevated concentrations of atherogenic cholesterol-containing lipoproteins, including very low-density lipoprotein cholesterol...

... This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Aims Atherosclerosis is a chronic condition characterized by persistent inflammation and vascular...

... the original work is properly cited. Abstract Peripheral artery disease (PAD) is a prevalent manifestation of systemic atherosclerosis, associated with elevated risks of major adverse cardiovascular events (MACE) and major adverse limb events (MALE). Despite its clinical significance, PAD remains...

..., and reproduction in any medium, provided the original work is properly cited. Abstract Aims Aging is a major risk factor for cardiovascular disease (CVD) and is also linked to a functional decline of the immune system. B cells contribute to atherosclerosis progression by antibody secretion, antigen presentation...

... This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Aims Aspirin plus low-dose rivaroxaban reduces cardiovascular events in stable atherosclerosis; its...

... and the acquisition of mesenchymal characteristics, thereby promoting vascular dysfunction and plaque progression. In this review, we present a comprehensive and up-to-date (as of 15 April 2026) overview of the molecular drivers and experimental models of EndMT in atherosclerosis and critically evaluate current...

... is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Aims Atherosclerosis is currently evaluated by imaging, but scalable circulating biomarkers to detect its presence...

...-reuse-rights ) Abstract Aims A subset of endothelial cells referred to as immunomodulatory endothelial cells (IMEC) has been proposed to regulate T-cell responses in atherosclerosis and after myocardial infarction. Here, we studied the inflammation-induced emergence of IMEC and characterized...

... cytokine IL-18 has gained less attention. Here we aimed to assess the associations of IL-18 with risk of coronary events and severity of atherosclerosis. Methods and results The study included 4742 participants participating in a prospective Swedish Malmö Diet and Cancer (MDC) cohort study, 54 219...

..., thereby promoting atherosclerotic progression. Created in BioRender. Sachse, M. (2026) https://BioRender.com/ky15cio . For image description, please refer to the figure legend and surrounding text. Sulfatase-1 (SULF-1) Endothelial-to-mesenchymal transition Atherosclerosis This editorial refers...

... of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background and Aims Atherosclerosis (AS) and abdominal aortic aneurysm (AAA...