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Guideline-recommended medical therapy and outcomes in octogenarian patients with HFrEF
Y Z Sener and others
Background Heart failure with reduced ejection fraction (HFrEF) is common in octogenarians, yet this population is underrepresented in clinical trials. Advanced age, comorbidities, and treatment intolerance may limit the use of guideline-recommended medical therapy (GRMT). Real-world data on GRMT ...
Uric acid variation as a predictor of short- and long-term mortality in acute decompensated heart failure
F Bahouth and others
Background Acute decompensated heart failure is a life-threatening disease, with a high rate of incidence of 10-12/1000 person/year among adults older than 50 years, and more than 10% of adults older than 70 years. Treatment depends mostly on clinical volemic status, pulmonary congestion in ...
Health disparities in heart failure with reduced ejection fraction among immigrants in Sweden: data from the Swedish Heart Failure Registry
V Valente and others
Introduction Health disparities in HF related to being an immigrant have not been characterised, and the underlying potential mechanisms remain unclear. Purpose To investigate whether immigrant status is associated with all-cause and cardiovascular (CV) mortality and HF hospitalisation (HFH) in ...
Dysregulated myocardial water balance and adverse outcomes in heart failure with preserved ejection fraction: insights from the NETDiamond cohort CMR substudy
F Vasques-Novoa and others
Background Myocardial edema may impair relaxation, increase diastolic stiffness, and compromise perfusion, yet its presence and clinical relevance in heart failure with preserved ejection fraction (HFpEF) remain poorly defined. Aim To compare myocardial free water and interstitial expansion in ...
Clinical characteristics of a real-world remote monitoring cohort of crt-d/icd recipients
M J Primo and others
Background Remote monitoring (RM) of cardiac resynchronization therapy defibrillator (CRT-D) and implantable cardioverter-defibrillator (ICD) recipients enables continuous device-based surveillance, allowing early detection of arrhythmic events and physiological changes. Despite its growing ...
Viral respiratory tract infections in heart failure with mildly reduced and preserved ejection fraction: a secondary analysis of the FINEARTS-HF trial
R Helseth and others
Background Viral respiratory tract infections (VRTIs) may worsen outcomes in patients with heart failure with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) and are potentially preventable. We explored the frequency and implications of VRTIs in patients with HFmrEF/HFpEF treated in a ...
Mind the gap: sex disparities in heart failure efficiency clinic referrals
E Higgisson and others
Introduction Specialist heart failure (HF) services play a key role in optimisation of guideline-directed medical therapy, risk stratification, and patient education and empowerment. Sex-based differences in referral to specialist HF services remain incompletely characterised. We aimed to describe ...
Cardiovascular-kidney-metabolic overlap in patients hospitalized for heart failure across the ejection fraction spectrum
M Kittipibul and others
Introduction In clinical trial populations, cardiovascular-kidney-metabolic (CKM) conditions are common among patients with heart failure (HF) and associated with higher risk of adverse outcomes. However, among patients with HF in contemporary US clinical practice, little is known regarding the ...
Predictors of heart failure with reduced or mildly reduced ejection fraction development in hypertrophic cardiomyopathy: a single-centre study
H Santos Moreira and others
Introduction Heart failure (HF) development represents one of the most prevalent and clinically relevant complications among hypertrophic cardiomyopathy (HCM). Purpose To identify clinical and imagological predictors of new-onset HF with left ventricle (LV) reduced/mildy reduced ejection fraction ...
Prognostic impact of iron deficiency in patients hospitalised with acute decompensated heart failure with reduced ejection fraction and chronic kidney disease
V Dimitrova and others
Background Iron deficiency is a frequent comorbidity in patients with heart failure with reduced ejection fraction and is associated with impaired functional capacity and adverse outcomes. Data on the prognostic impact of iron deficiency in hospitalised patients with concomitant chronic kidney ...
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    2025 Impact Factor
  • 12.4
    2025 5 Year Impact Factor
  • 16/237
    Cardiac & Cardiovascular Systems (Rank by Impact Factor)
  • 19.7
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