Volume 153, Issue 3, 1 March 2012

News & Views

Social Status and Neurogenomic States

Catherine A. Marler

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1001–1002, https://doi.org/10.1210/en.2011-2152

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Maternal Iron Deficiency Heightens Fetal Susceptibility to Metabolic Syndrome in Adulthood

Miyako Furuta and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1003–1004, https://doi.org/10.1210/en.2011-2116

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Capricious Cre: The Devil Is in the Details

Christopher D. Morrison and Heike Münzberg

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1005–1007, https://doi.org/10.1210/en.2011-2169

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Diabetic Nephropathy: Do Cannabinoids Contribute?

Leon A. Bach

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1008–1009, https://doi.org/10.1210/en.2012-1027

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One Step from Prediabetes to Diabetes: Hypothalamic Inflammation?

Dongsheng Cai

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1010–1013, https://doi.org/10.1210/en.2011-2183

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Allosteric Modulators of the Calcium-Sensing Receptor: Turning News into Distinct Views

Markus R. John

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1014–1015, https://doi.org/10.1210/en.2012-1006

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Minireviews

Minireview: Endocannabinoids and Gonadal Hormones: Bidirectional Interactions in Physiology and Behavior

Boris B. Gorzalka and Silvain S. Dang

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1016–1024, https://doi.org/10.1210/en.2011-1643

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Minireview: Epigenetics of Obesity and Diabetes in Humans

Howard Slomko and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1025–1030, https://doi.org/10.1210/en.2011-1759

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Minireview: Epigenetic Programming of Diabetes and Obesity: Animal Models

Yoshinori Seki and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1031–1038, https://doi.org/10.1210/en.2011-1805

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Minireview: Glucagon in the Pathogenesis of Hypoglycemia and Hyperglycemia in Diabetes

Philip E. Cryer

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1039–1048, https://doi.org/10.1210/en.2011-1499

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Minireview: Glucagon in Stress and Energy Homeostasis

B. J. Jones and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1049–1054, https://doi.org/10.1210/en.2011-1979

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Minireview: The Role of the Autonomic Nervous System in Mediating the Glucagon Response to Hypoglycemia

Gerald J. Taborsky and Thomas O. Mundinger

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1055–1062, https://doi.org/10.1210/en.2011-2040

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Brief Report

Dynamic Regulation of Wnt7a Expression in the Primate Endometrium: Implications for Postmenstrual Regeneration and Secretory Transformation

Xiujun Fan and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1063–1069, https://doi.org/10.1210/en.2011-1826

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Cancer-Oncogenes

Preclinical Characterization of a Novel Diphenyl Benzamide Selective ERα Agonist for Hormone Therapy in Prostate Cancer

Christopher C. Coss and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1070–1081, https://doi.org/10.1210/en.2011-1608

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Diabetes-Insulin-Glucagon-Gastrointestinal

Pro-GRP-Derived Peptides Are Expressed in Colorectal Cancer Cells and Tumors and Are Biologically Active in Vivo

Oneel Patel and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1082–1092, https://doi.org/10.1210/en.2011-1875

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Impact of the Dipeptidyl Peptidase-4 Inhibitor Vildagliptin on Glucose Tolerance and β-Cell Function and Mass in Insulin Receptor Substrate-2-Knockout Mice Fed a High-Fat Diet

Koichiro Sato and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1093–1102, https://doi.org/10.1210/en.2011-1712

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Improved Insulin Sensitivity after Long-Term Treatment with AT₁ Blockers Is Not Associated with PPARγ Target Gene Regulation

Helge Müller-Fielitz and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1103–1115, https://doi.org/10.1210/en.2011-0183

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Antiapoptotic Actions of Exendin-4 against Hypoxia and Cytokines Are Augmented by CREB

Kalpana Velmurugan and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1116–1128, https://doi.org/10.1210/en.2011-1895

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Differential Insulin Receptor Substrate-1 (IRS1)-Related Modulation of Neuropeptide Y and Proopiomelanocortin Expression in Nondiabetic and Diabetic IRS2^−/− Mice

Emma Burgos-Ramos and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1129–1140, https://doi.org/10.1210/en.2011-1278

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Disruption of the Murine Glp2r Impairs Paneth Cell Function and Increases Susceptibility to Small Bowel Enteritis

Seung-Jun Lee and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1141–1151, https://doi.org/10.1210/en.2011-1954

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Prediabetic Nephropathy as an Early Consequence of the High-Calorie/High-Fat Diet: Relation to Oxidative Stress

Hanna Shevalye and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1152–1161, https://doi.org/10.1210/en.2011-1997

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Energy Balance-Obesity

Peroxisome Proliferator-Activated Receptors-α and -γ, and cAMP-Mediated Pathways, Control Retinol-Binding Protein-4 Gene Expression in Brown Adipose Tissue

Meritxell Rosell and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1162–1173, https://doi.org/10.1210/en.2011-1367

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Perinatal Iron Deficiency Combined with a High-Fat Diet Causes Obesity and Cardiovascular Dysregulation

Stephane L. Bourque and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1174–1182, https://doi.org/10.1210/en.2011-1700

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Lipocalin 2 Deficiency Alters Estradiol Production and Estrogen Receptor Signaling in Female Mice

Hong Guo and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1183–1193, https://doi.org/10.1210/en.2011-1642

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Ghrelin Interacts with Neuropeptide Y Y1 and Opioid Receptors to Increase Food Reward

Karolina P. Skibicka and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1194–1205, https://doi.org/10.1210/en.2011-1606

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The Ubiquitin Ligase Siah2 Regulates PPARγ Activity in Adipocytes

Gail Kilroy and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1206–1218, https://doi.org/10.1210/en.2011-1725

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Defining POMC Neurons Using Transgenic Reagents: Impact of Transient Pomc Expression in Diverse Immature Neuronal Populations

Stephanie L. Padilla and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1219–1231, https://doi.org/10.1210/en.2011-1665

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General Endocrinology

Positive and Negative Allosteric Modulators Promote Biased Signaling at the Calcium-Sensing Receptor

Anna E. Davey and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1232–1241, https://doi.org/10.1210/en.2011-1426

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Brown Fat Lipoatrophy and Increased Visceral Adiposity through a Concerted Adipocytokines Overexpression Induces Vascular Insulin Resistance and Dysfunction

Almudena Gómez-Hernández and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1242–1255, https://doi.org/10.1210/en.2011-1765

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Angiotensin II-Dependent Transcriptional Activation of Human Steroidogenic Acute Regulatory Protein Gene by a 25-kDa cAMP-Responsive Element Modulator Protein Isoform and Yin Yang 1

Renate K. Meier and Barbara J. Clark

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1256–1268, https://doi.org/10.1210/en.2011-1744

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Antiapolipoprotein A-1 IgG Chronotropic Effects Require Nongenomic Action of Aldosterone on L-Type Calcium Channels

Michel F. Rossier and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1269–1278, https://doi.org/10.1210/en.2011-1835

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Physiological Responses to Acute Psychological Stress Are Reduced by the PPARγ Agonist Rosiglitazone

Karen K. Ryan and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1279–1287, https://doi.org/10.1210/en.2011-1689

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Glucocorticoids-CRH-ACTH-Adrenal

Glucocorticoid Receptor Signaling Is Essential for Mesoderm Formation and Muscle Development in Zebrafish

Dinushan Nesan and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1288–1300, https://doi.org/10.1210/en.2011-1559

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Growth Factors-Cytokines

Activation of Latent Human GDF9 by a Single Residue Change (Gly³⁹¹Arg) in the Mature Domain

Courtney M. Simpson and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1301–1310, https://doi.org/10.1210/en.2011-1632

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Neuroendocrinology

Reduced Hippocampal Brain-Derived Neurotrophic Factor (BDNF) in Neonatal Rats after Prenatal Exposure to Propylthiouracil (PTU)

Goutam Chakraborty and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1311–1316, https://doi.org/10.1210/en.2011-1437

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Reactive Oxygen Species Are Required for the Hypothalamic Osmoregulatory Response

Ronald St-Louis and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1317–1329, https://doi.org/10.1210/en.2011-1350

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Mineralocorticoid Receptor Overexpression Facilitates Differentiation and Promotes Survival of Embryonic Stem Cell-Derived Neurons

Mathilde Munier and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1330–1340, https://doi.org/10.1210/en.2011-1436

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Social Status Predicts How Sex Steroid Receptors Regulate Complex Behavior across Levels of Biological Organization

Lauren A. O'Connell and Hans A. Hofmann

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1341–1351, https://doi.org/10.1210/en.2011-1663

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Stimulatory Effect of RFRP-3 on the Gonadotrophic Axis in the Male Syrian Hamster: The Exception Proves the Rule

Caroline Ancel and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1352–1363, https://doi.org/10.1210/en.2011-1622

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Rapid and Widespread Effects of 17β-Estradiol on Intracellular Signaling in the Male Songbird Brain: A Seasonal Comparison

Sarah A. Heimovics and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1364–1376, https://doi.org/10.1210/en.2011-1525

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Molecular Characterization and Biological Function of Neuroendocrine Regulatory Peptide-3 in the Rat

Hiroaki Fujihara and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1377–1386, https://doi.org/10.1210/en.2011-1539

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Renal-Cardiac-Vascular

Blockade of Cannabinoid Receptor 1 Improves Insulin Resistance, Lipid Metabolism, and Diabetic Nephropathy in db/db Mice

D. H. Nam and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1387–1396, https://doi.org/10.1210/en.2011-1423

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Early Postnatal Hyperalimentation Impairs Renal Function via SOCS-3 Mediated Renal Postreceptor Leptin Resistance

Miguel Angel Alejandre Alcazar and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1397–1410, https://doi.org/10.1210/en.2011-1670

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Angiotensin II Reduces Food Intake by Altering Orexigenic Neuropeptide Expression in the Mouse Hypothalamus

Tadashi Yoshida and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1411–1420, https://doi.org/10.1210/en.2011-1764

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Reproduction-Development

Targeted Pituitary Overexpression of Pituitary Adenylate-Cyclase Activating Polypeptide Alters Postnatal Sexual Maturation in Male Mice

Joseph P. Moore and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1421–1434, https://doi.org/10.1210/en.2011-1115

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Phylogenetic Comparisons Implicate Sex Hormone-Binding Globulin in “Masculinization” of the Female Spotted Hyena (Crocuta crocuta)

Geoffrey L. Hammond and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1435–1443, https://doi.org/10.1210/en.2011-1837

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Activation of Southern White Rhinoceros (Ceratotherium simum simum) Estrogen Receptors by Phytoestrogens: Potential Role in the Reproductive Failure of Captive-Born Females?

Christopher Tubbs and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1444–1452, https://doi.org/10.1210/en.2011-1962

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Expression and Regulation of Human Fetal-Specific CYP3A7 in Mice

Xiao-Yan Pang and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1453–1463, https://doi.org/10.1210/en.2011-1020

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Differential Regulation of Glucose Transporters Mediated by CRH Receptor Type 1 and Type 2 in Human Placental Trophoblasts

Lu Gao and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1464–1471, https://doi.org/10.1210/en.2011-1673

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Norepinephrine, Active Norepinephrine Transporter, and Norepinephrine-Metabolism Are Involved in the Generation of Reactive Oxygen Species in Human Ovarian Granulosa Cells

S. Saller and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1472–1483, https://doi.org/10.1210/en.2011-1769

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The Loss of Hoxa5 Function Causes Estrous Acyclicity and Ovarian Epithelial Inclusion Cysts

Gaëlle Gendronneau and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1484–1497, https://doi.org/10.1210/en.2011-1766

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Uncovering Novel Reproductive Defects in Neurokinin B Receptor Null Mice: Closing the Gap Between Mice and Men

Jasmine J. Yang and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1498–1508, https://doi.org/10.1210/en.2011-1949

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A Covalently Dimerized Recombinant Human Bone Morphogenetic Protein-15 Variant Identifies Bone Morphogenetic Protein Receptor Type 1B as a Key Cell Surface Receptor on Ovarian Granulosa Cells

Minna M. Pulkki and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1509–1518, https://doi.org/10.1210/en.2010-1390

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Technical Communication

Quantitative Measurement of Full-Length and C-Terminal Proteolyzed RBP4 in Serum of Normal and Insulin-Resistant Humans using a Novel Mass Spectrometry Immunoassay

Qin Yang and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1519–1527, https://doi.org/10.1210/en.2011-1750

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Thyroid-TRH-TSH

Impact of Oatp1c1 Deficiency on Thyroid Hormone Metabolism and Action in the Mouse Brain

Steffen Mayerl and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1528–1537, https://doi.org/10.1210/en.2011-1633

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GLP-1 Receptor Agonists and the Thyroid: C-Cell Effects in Mice Are Mediated via the GLP-1 Receptor and not Associated with RET Activation

Lars Wichmann Madsen and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1538–1547, https://doi.org/10.1210/en.2011-1864

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Thyroid Hormone Receptors Control Developmental Maturation of the Middle Ear and the Size of the Ossicular Bones

Emily A. Cordas and others

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1548–1560, https://doi.org/10.1210/en.2011-1834

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Translational Highlights

Translational Highlights from The Journal of Clinical Endocrinology & Metabolism

Endocrinology, Volume 153, Issue 3, 1 March 2012, Pages 1561–1564, https://doi.org/10.1210/endo.153.3.zee1561

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