Volume 152, Issue 5, 1 May 2011

News and Views

Time for Testosterone: The Suprachiasmatic Nucleus Gets Sexy

Megan H. Hagenauer and Theresa M. Lee

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1727–1730, https://doi.org/10.1210/en.2011-0198

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Agnostic about in Vivo Inverse Agonism of Agouti-Related Peptide

Malcolm J. Low

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1731–1733, https://doi.org/10.1210/en.2011-0232

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Naughty Melatonin: How Mothers Tick Off their Fetus

Valérie Simonneaux

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1734–1738, https://doi.org/10.1210/en.2011-0226

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Autophagy's Expanding Role in Development: Implantation Is Next

D. Randall Armant

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1739–1741, https://doi.org/10.1210/en.2011-0220

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The Role Played by the Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) Activator, GW501516, in Control of Fatty Acid Metabolism: A New Potential Therapeutic Target for Treating Metabolic Syndrome

Jandee Lee and Woong Youn Chung

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1742–1744, https://doi.org/10.1210/en.2011-0211

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Brief Report

17β-Estradiol Increases Astrocytic Vascular Endothelial Growth Factor (VEGF) in Adult Female Rat Hippocampus

Sharon Barouk and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1745–1751, https://doi.org/10.1210/en.2010-1290

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Commentary

Commentary: Androgens and “Anabolic Steroids”: The One-Headed Janus

David J. Handelsman

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1752–1754, https://doi.org/10.1210/en.2010-1501

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Calcium-Regulating Hormones

Deletion of Glycogen Synthase Kinase-3β in Cartilage Results in Up-Regulation of Glycogen Synthase Kinase-3α Protein Expression

J. R. Gillespie and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1755–1766, https://doi.org/10.1210/en.2010-1412

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Teriparatide [rhPTH (1-34)], But Not Strontium Ranelate, Demonstrated Bone Anabolic Efficacy in Mature, Osteopenic, Ovariectomized Rats

Yanfei L. Ma and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1767–1778, https://doi.org/10.1210/en.2010-1112

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Diabetes-Insulin-Glucagon-Gastrointestinal

Dynamic Regulation of PDX-1 and FoxO1 Expression by FoxA2 in Dexamethasone-Induced Pancreatic β-cells Dysfunction

Fang Chen and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1779–1788, https://doi.org/10.1210/en.2010-1048

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Telmisartan Improves Insulin Resistance and Modulates Adipose Tissue Macrophage Polarization in High-Fat-Fed Mice

Shiho Fujisaka and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1789–1799, https://doi.org/10.1210/en.2010-1312

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Protein Phosphatase 1 (PP-1)-Dependent Inhibition of Insulin Secretion by Leptin in INS-1 Pancreatic β-Cells and Human Pancreatic Islets

Peter Kuehnen and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1800–1808, https://doi.org/10.1210/en.2010-1094

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Energy Balance-Obesity

Differential Acute and Chronic Effects of Leptin on Hypothalamic Astrocyte Morphology and Synaptic Protein Levels

Cristina García-Cáceres and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1809–1818, https://doi.org/10.1210/en.2010-1252

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Loss of Agouti-Related Peptide Does Not Significantly Impact the Phenotype of Murine POMC Deficiency

Marcus P. Corander and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1819–1828, https://doi.org/10.1210/en.2010-1450

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Inhibition of Glyceroneogenesis by Histone Deacetylase 3 Contributes to Lipodystrophy in Mice with Adipose Tissue Inflammation

Jin Zhang and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1829–1838, https://doi.org/10.1210/en.2010-0828

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General Endocrinology

Calcitropic Hormones and IGF-I Are Influenced by Dietary Protein

Victor Dubois-Ferrière and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1839–1847, https://doi.org/10.1210/en.2010-1079

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The PPARβ/δ Activator GW501516 Prevents the Down-Regulation of AMPK Caused by a High-Fat Diet in Liver and Amplifies the PGC-1α-Lipin 1-PPARα Pathway Leading to Increased Fatty Acid Oxidation

Emma Barroso and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1848–1859, https://doi.org/10.1210/en.2010-1468

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The Conserved Clusterin Gene Is Expressed in the Developing Choroid Plexus Under the Regulation of Notch But Not IGF Signaling in Zebrafish

Shuang Jiao and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1860–1871, https://doi.org/10.1210/en.2010-1183

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Regulation by Heat Shock Protein 27 of Osteocalcin Synthesis in Osteoblasts

Kenji Kato and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1872–1882, https://doi.org/10.1210/en.2010-1062

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Glucocorticoids-CRH-ACTH-Adrenal

Mineralocorticoid Receptors: Evolutionary and Pathophysiological Considerations

Karin S. Kassahn and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1883–1890, https://doi.org/10.1210/en.2010-1444

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A Circadian Clock Entrained by Melatonin Is Ticking in the Rat Fetal Adrenal

C. Torres-Farfan and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1891–1900, https://doi.org/10.1210/en.2010-1260

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Reciprocal Regulation of TREK-1 Channels by Arachidonic Acid and CRH in Mouse Corticotropes

Andy K. Lee and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1901–1910, https://doi.org/10.1210/en.2010-1066

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Growth Factors-Cytokines

Interleukin-33, a Target of Parathyroid Hormone and Oncostatin M, Increases Osteoblastic Matrix Mineral Deposition and Inhibits Osteoclast Formation in Vitro

Hasnawati Saleh and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1911–1922, https://doi.org/10.1210/en.2010-1268

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Loss of IGF-IEa or IGF-IEb Impairs Myogenic Differentiation

Ronald W. Matheny and Bradley C. Nindl

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1923–1934, https://doi.org/10.1210/en.2010-1279

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Tracking the Activation of Stat5 through the Expression of an Inducible Reporter Gene in a Transgenic Mouse Line

Nadja Lydia Bednorz and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1935–1947, https://doi.org/10.1210/en.2011-0053

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Growth Hormone-Somatostatin-GRH

Lack of Dietary Carbohydrates Induces Hepatic Growth Hormone (GH) Resistance in Rats

Maximilian Bielohuby and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1948–1960, https://doi.org/10.1210/en.2010-1423

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Neuroendocrinology

Expression of Insulinoma-Associated 2 (INSM2) in Pancreatic Islet Cells Is Regulated by the Transcription Factors Ngn3 and NeuroD1

Tao Cai and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1961–1969, https://doi.org/10.1210/en.2010-1065

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Androgens Modulate Structure and Function of the Suprachiasmatic Nucleus Brain Clock

Ilia N. Karatsoreos and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1970–1978, https://doi.org/10.1210/en.2010-1398

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Region-, Neuron-, and Signaling Pathway-Specific Increases in Prolactin Responsiveness in Reproductively Experienced Female Rats

Annika Sjoeholm and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1979–1988, https://doi.org/10.1210/en.2010-1220

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Thyroid Hormone Regulates the Expression of the Sonic Hedgehog Signaling Pathway in the Embryonic and Adult Mammalian Brain

Lynette A. Desouza and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 1989–2000, https://doi.org/10.1210/en.2010-1396

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Androgenic Influence on Serotonergic Activation of the HPA Stress Axis

Nirupa Goel and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2001–2010, https://doi.org/10.1210/en.2010-0964

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Spatially Selective, Testosterone-Independent Remodeling of Dendrites in Gonadotropin-Releasing Hormone (GnRH) Neurons Prepubertally in Male Rats

Natividad Ybarra and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2011–2019, https://doi.org/10.1210/en.2010-0871

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Regulation of Kiss1 Expression by Sex Steroids in the Amygdala of the Rat and Mouse

Joshua Kim and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2020–2030, https://doi.org/10.1210/en.2010-1498

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Renal-Cardiac-Vascular

Genetic Ablation of Sfrp4 in Mice Does Not Affect Serum Phosphate Homeostasis

Marta Christov and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2031–2036, https://doi.org/10.1210/en.2010-1351

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Regulation of MT1-MMP and MMP-2 by Leptin in Cardiac Fibroblasts Involves Rho/ROCK-Dependent Actin Cytoskeletal Reorganization and Leads to Enhanced Cell Migration

Kristin Schram and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2037–2047, https://doi.org/10.1210/en.2010-1166

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Reproduction-Development

Prenatal Androgen Exposure Leads to Alterations in Gene and Protein Expression in the Ovine Fetal Ovary

Kirsten Hogg and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2048–2059, https://doi.org/10.1210/en.2010-1219

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Maternal Ghrelin Deficiency Compromises Reproduction in Female Progeny through Altered Uterine Developmental Programming

J. Ryan Martin and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2060–2066, https://doi.org/10.1210/en.2010-1485

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Autophagy Regulates Embryonic Survival During Delayed Implantation

Jong-Eun Lee and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2067–2075, https://doi.org/10.1210/en.2010-1456

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Smad3 Dosage Determines Androgen Responsiveness and Sets the Pace of Postnatal Testis Development

Catherine Itman and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2076–2089, https://doi.org/10.1210/en.2010-1453

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Effects of Resveratrol, a Grape Polyphenol, on Uterine Contraction and Ca²⁺ Mobilization in Rats in Vivo and in Vitro

Shih-Min Hsia and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2090–2099, https://doi.org/10.1210/en.2010-1223

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DNA Methylation of Intronic Enhancers Directs Tissue-Specific Expression of Steroidogenic Factor 1/Adrenal 4 Binding Protein (SF-1/Ad4BP)

Erling A. Hoivik and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2100–2112, https://doi.org/10.1210/en.2010-1305

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PTGS2 (Prostaglandin Endoperoxide Synthase-2) Expression in Term Human Amnion in Vivo Involves Rapid mRNA Turnover, Polymerase-II 5′-Pausing, and Glucocorticoid Transrepression

Carolyn Mitchell and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2113–2122, https://doi.org/10.1210/en.2010-1327

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Technical Communication

Quantitative Analysis of Glucose Transporter mRNAs in Endometrial Stromal Cells Reveals Critical Role of GLUT1 in Uterine Receptivity

Antonina I. Frolova and Kelle H. Moley

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2123–2128, https://doi.org/10.1210/en.2010-1266

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Translational Highlights

Psychological Assessment of Primary Aldosteronism: A Controlled Study

Nicoletta Sonino and others

Endocrinology, Volume 152, Issue 5, 1 May 2011, Pages 2129–2132, https://doi.org/10.1210/endo.152.5.zee2129

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