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RICHARD E. WHALEN, JOSEPH F. DEBOLD, Comparative Effectiveness of Testosterone, Androstenedione and Dihydrotestosterone in Maintaining Mating Behavior in the Castrated Male Hamster, Endocrinology, Volume 95, Issue 6, 1 December 1974, Pages 1674–1679, https://doi.org/10.1210/endo-95-6-1674
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Adult male hamsters were castrated after displaying the full copulatory pattern including ejaculation. Some animals were given control vehicle injections, while others received injections of testosterone, androstenedione or dihydrotestosterone. Animals were tested at the following daily doses of androgen: 1000 µg, 500 µg, 250 µg, 200 µg, 100. µg, 50 µg and 0 µg. Vehicle-treated animals ceased mating a few weeks after castration with the exception of occasional mounting responses. All three androgens maintained mating although to different degrees. Androstenedione was slightly more effective than testosterone and both of these steroids were substantially, more effective than dihydrotestosterone. The data were taken to mean that neither aromatization nor 5α-reduction processes are critical in the androgenic control of mating in this species. (Endocrinology95: 1674, 1974).
