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BILL R. HOPPER, WILLIAM W. TULLNER, Urinary Estrogen Excretion After ACTH in Ovariectomized Monkeys (Macaca mulatto), Endocrinology, Volume 82, Issue 4, 1 April 1968, Pages 876–877, https://doi.org/10.1210/endo-82-4-876
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Endometrial stimulation after ACTH treatment of ovariectomized rhesus monkeys (Macaca mulatto) provided physiological evidence for estrogen production as a result of adrenal stimulation. In further studies, urinary estrogen excretion was evaluated by means of thin-layer and gas-liquid chromatography both before and after ACTH treatment in ovariectomized and ovariectomized-adrenalectomized monkeys. Estrogens (estrone, estradiol-17β and estriol) were undetectable before ACTH. Only estrone was found in the urine of ovariectomized monkeys after ACTH (80 USP units daily for 2–4 weeks). (Endocrinology82: 876, 1968)