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MARY E. O’SULLIVAN, THE PRESENT DAY STATUS OF MIGRAINE THERAPY, Endocrinology, Volume 24, Issue 3, 1 March 1939, Pages 414–418, https://doi.org/10.1210/endo-24-3-414
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Abstract
FOR THE PAST five years, we have been carrying on research in migraine on the Neurological Service at Bellevue Hospital, under the direction of Dr. Foster Kennedy. During this time, we have treated three hundred patients. The following is a clinical résumé of our therapeutic methods and result.
It is our belief that to satisfactorily treat migraine, one must accept the concept of the conglomerative character of the syndrome. We must treat the condition not as a clinical entity with one cause and one specific cure, but as a clinical symptom that is indicative of some underlying pathological process. This underlying pathological process, whatever it may be, must be determined and treated before one can expect to relieve the suffering of migraine.
Although it is generally admitted that migraine is a syndrome, this concept is neglected by investigators in their therapeutic discussions. The medical literature contains many reports of successful migraine therapy.