
Contents
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Acute Inflammation: An Essential Response to Infections and Injuries Acute Inflammation: An Essential Response to Infections and Injuries
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Chronic Inflammation and Health Chronic Inflammation and Health
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Acute Stress and Inflammation Acute Stress and Inflammation
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Chronic Stress and Inflammation Chronic Stress and Inflammation
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Depression, Mood, and Inflammation Depression, Mood, and Inflammation
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Pharmacologically-induced Inflammation is Associated with Depression Pharmacologically-induced Inflammation is Associated with Depression
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Depression Treatment Leads to Reduction in Inflammation Depression Treatment Leads to Reduction in Inflammation
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Association Between Depression and Inflammation in Epidemiological and Clinical Studies Association Between Depression and Inflammation in Epidemiological and Clinical Studies
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Chronic Diseases, Inflammation, and Depression Chronic Diseases, Inflammation, and Depression
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Bidirectional Relationships Between Mood and Inflammation Bidirectional Relationships Between Mood and Inflammation
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Other Negative Emotions and Inflammation Other Negative Emotions and Inflammation
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Cross-sensitization: Stress, Depression, and Inflammation Cross-sensitization: Stress, Depression, and Inflammation
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Social Relationships and Inflammation Social Relationships and Inflammation
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Behavioral Pathways Linking Negative Emotions and Inflammation Behavioral Pathways Linking Negative Emotions and Inflammation
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Physiological Pathways Linking Negative Emotions and Inflammation Physiological Pathways Linking Negative Emotions and Inflammation
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Regulation of Monoamines Regulation of Monoamines
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Glucocorticoid Resistance Glucocorticoid Resistance
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Molecular Mechanism Linking Stress and Inflammation Molecular Mechanism Linking Stress and Inflammation
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Conclusion Conclusion
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Acknowledgments Acknowledgments
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References References
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54 Stress, Negative Emotions, and Inflammation
Get accessJean-Philippe Gouin, Department of Psychology, Ohio State University.
Liisa V. Hantsoo, Department of Psychology, Ohio State University.
Janice K. Kiecolt-Glaser, Department of Psychiatry, Ohio State University College of Medicine.
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Published:18 September 2012
Cite
Abstract
Chronic low grade inflammation is a core pathophysiological process that may be involved in many age-related diseases. Elevations in circulating markers of inflammation have been associated with frailty and disability, osteoporosis, certain cancers, cardiovascular disorders, type II diabetes, rheumatoid arthritis, and Alzheimer’s disease. Importantly, stress and negative emotions appear to promote the production of inflammatory mediators, providing a physiological mechanism by which negative psychological states may impact health. This chapter reviews the basic physiological processes of inflammation, the relationships among stress, negative emotions, social relationships, and inflammation, and the behavioral and physiological pathways linking stress, emotions, and inflammation.
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