Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure Free

Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure (Cardiovasc Res 2020;87:524–534; https://doi.org/10.1093/cvr/cvq068).

A member of staff of the Cleveland Clinic Foundation alerted the Editors of Cardiovascular Research in a letter regarding concerns about the data presented in Figure 1A and 7 of the above mentioned manuscript.

The concern regarding Figure 7 was initially brought to the attention of Cleveland Clinic by a reader and further investigated by the Commission of Investigation at Cleveland Clinic. In addition to the concern raised by the reader, the Commission of Investigation also found an additional concern regarding Figure 1. Cleveland Clinic’s Board of Governors/Medical Executive Committee concurred with the Commission of Investigation’s findings. The Editors of Cardiovascular Research have decided to place an expression of concern related to this manuscript to inform readers appropriately whilst an investigation takes place.