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Hiroshi Suginome, J B Wang, Replacement of an 11-Carbonyl Group of 11-Oxo Steroid by an Oxygen Atom. A New Partial Synthesis of 11-Oxaprogesterone, Bulletin of the Chemical Society of Japan, Volume 62, Issue 1, January 1989, Pages 193–197, https://doi.org/10.1246/bcsj.62.193
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Abstract
We describe the transformation of commercially available 3α-hydroxy-5β-pregnane-11,20-dione acetate (1) into 11-oxaprogesterone (15) in 11 steps including the regioselective β-scission of an alkoxyl radical as a key step.
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© 1989 The Chemical Society of Japan
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