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B. M. Greenwood, P. G. Cleland, M. H. K. Haggie, L. S. Lewis, J. T. Macfarlane, A. Taqi, H. C. Whittle, An epidemic of meningococcal infection at Zaria, Northern Nigeria. 2. The changing clinical pattern, Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 73, Issue 5, 1979, Pages 563–566, https://doi.org/10.1016/0035-9203(79)90053-1
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Abstract
1,003 patients with meningococcal disease admitted to a single hospital during the course of a three-month epidemic were studied. A progressive decline in mortality, especially among patients with acute meningococcaemia, and a falling incidence of systemic and severe neurological complications among patients with meningitis were observed. It is suggested that the virulence of the causative group A meningococcus declined as the epidemic progressed.
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