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F. Partono, Purnomo, A. Soewarta, A simple method to control Brugia timori by diethylcarbamazine administration, Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 73, Issue 5, 1979, Pages 536–542, https://doi.org/10.1016/0035-9203(79)90046-4
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Abstract
The results of mass treatment using 50 mg diethylcarbamazine per kg body-weight followed one year later by short term selective re-treatment in a highly endemic area of Brugia timori are described. The criteria for selection of re-treatment are simple and practical for use in rural areas. The microfilaria rate by finger prick decreased from 24% to 0 and by NucleporeR filtration from 30% to 2·5%. The disease rates were also affected favourably. 88% of persons receiving the drug reacted to treatment, this percentage slightly exceeding the total filarial infection rate (71%). The prevalence, onset, duration and nature of side reactions are briefly discussed and related to the presence of microfilaraemia and disease manifestations among the study population.
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