Volume 160, Issue 1
November 2017
Cover image
Cover image
Cover illustrations. Principal component analysis of androstenedione effects on gene expression from Rooney et al., 15–29. Histopathological changes in brain after sarin intoxication from Chaubey et al., 136–149. Using microelectrode arrays to study cortical activity after toxicant exposure from Frank et al., 121–135. Histological analysis of lung-specifi c over-expression of IKK2ca from Chen et al., 4–14.
ISSN 1096-6080
EISSN 1096-0929
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Volume 160, Issue 1, November 2017
LOOK INSIDE TOXSCI
From the Editor's Desk, Editor's Highlights
Toxicological Sciences, Volume 160, Issue 1, November 2017, Page 1, https://doi.org/10.1093/toxsci/kfx205
LETTERS TO THE EDITOR
Overgeneralization by Mesnage et al. Regarding Bisphenol A Alternatives
Toxicological Sciences, Volume 160, Issue 1, November 2017, Page 2, https://doi.org/10.1093/toxsci/kfx167
No Overgeneralization in Mesnage et al. Regarding Bisphenol A Alternatives: Response
Toxicological Sciences, Volume 160, Issue 1, November 2017, Page 3, https://doi.org/10.1093/toxsci/kfx168
OVEREXPRESSION OF IKK2 AND PULMONARY INFLAMMATION
From the Cover: Lung-Specific Overexpression of Constitutively Active IKK2 Induces Pulmonary and Systemic Inflammations but Not Hypothalamic Inflammation and Glucose Intolerance
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 4–14, https://doi.org/10.1093/toxsci/kfx154
ANDROSTENEDIONE AND CANCER SUSCEPTIBILITY
From the Cover: Genomic Effects of Androstenedione and Sex-Specific Liver Cancer Susceptibility in Mice
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 15–29, https://doi.org/10.1093/toxsci/kfx153
ANTITUMOR EFFECTS OF AZT DERIVATIVES
Chalcogenozidovudine Derivatives With Antitumor Activity: Comparative Toxicities in Cultured Human Mononuclear Cells
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 30–46, https://doi.org/10.1093/toxsci/kfx152
OCCUPATIONAL THRESHOLDS FOR AIRBORNE ORGANIC CHEMICALS
Derivation of Occupational Thresholds of Toxicological Concern for Systemically Acting Noncarcinogenic Organic Chemicals
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 47–56, https://doi.org/10.1093/toxsci/kfx155
AOP FOR THYROID HORMONE SYNTHESIS INHIBITION AND NEURODEVELOPMENT
Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 57–73, https://doi.org/10.1093/toxsci/kfx163
ARYL HYDROCARBON RECEPTOR IN CARDIAC DIFFERENTIATION AND DYSFUNCTION
Aryl Hydrocarbon Receptor Ablation in Cardiomyocytes Protects Male Mice From Heart Dysfunction Induced by NKX2.5 Haploinsufficiency
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 74–82, https://doi.org/10.1093/toxsci/kfx164
ARYL HYDROCARBON RECEPTOR ACTIVATION AND NEUTROPHIL FUNCTION
Editor’s Highlight: Ah Receptor Activation Potentiates Neutrophil Chemoattractant (C-X-C Motif) Ligand 5 Expression in Keratinocytes and Skin
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 83–94, https://doi.org/10.1093/toxsci/kfx160
TRANSCRIPTOMIC ANALYSIS OF TCE AND PCE IN LIVER AND KIDNEY
Editor’s Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 95–110, https://doi.org/10.1093/toxsci/kfx165
FUNCTIONAL GENOMICS OF TCE METABOLITES GENOTOXICITY
Editor’s Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 111–120, https://doi.org/10.1093/toxsci/kfx159
MICROELECTRODE ARRAY SCREENING OF DEVELOPMENTAL NEUROTOXICANTS
From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 121–135, https://doi.org/10.1093/toxsci/kfx169
SARIN EXPOSURE AND RAT BRAIN PROTEOMICS
From the Cover: Proteome Profile of Different Rat Brain Regions After Sarin Intoxication
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 136–149, https://doi.org/10.1093/toxsci/kfx162
TRICLOSAN EXPOSURE IN PREGNANT MICE INDUCES INSULIN RESISTANCE
Exposure of Pregnant Mice to Triclosan Causes Insulin Resistance via Thyroxine Reduction
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 150–160, https://doi.org/10.1093/toxsci/kfx166
DEXRAZOXANE COUNTERS GENOMIC DAMAGE INDUCED BY IDARUBICIN
Dexrazoxane Averts Idarubicin-Evoked Genomic Damage by Regulating Gene Expression Profiling Associated With the DNA Damage-Signaling Pathway in BALB/c Mice
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 161–172, https://doi.org/10.1093/toxsci/kfx161
INCREASED AFLATOXIN B1 DAMAGE IN PREGNANT MICE
Editor’s Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 173–179, https://doi.org/10.1093/toxsci/kfx171
DIBUTYL PHTHALATE EFFECTS IN HUMAN GRANULOSA CELLS
In Vitro Exposure of Human Luteinized Mural Granulosa Cells to Dibutyl Phthalate Affects Global Gene Expression
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 180–188, https://doi.org/10.1093/toxsci/kfx170
CORRIGENDUM
Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening
Toxicological Sciences, Volume 160, Issue 1, November 2017, Pages 189–190, https://doi.org/10.1093/toxsci/kfx194
