Volume 159, Issue 2
October 2017
Cover image
Cover image
Cover illustrations. Quantifi cation of single cell actin cytoskeletal network from Yin et al., 307–326. Immunohistochemical characterization of iPSC-derived dopamine neurons from Neely et al., 366–379. Alcohol-induced cardiac fi brotic remodeling from Yan et al., 392–401. Histopathologicla analysis of mouse tissues after exposure to silver nanoparticles from Jarak et al., 422–435.
ISSN 1096-6080
EISSN 1096-0929
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Volume 159, Issue 2, October 2017
LOOK INSIDE TOXSCI
From the Editor's Desk, Editor's Highlights
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 277–278, https://doi.org/10.1093/toxsci/kfx173
FORUM: FLUTAMIDE PERMITTED DAILY EXPOSURE
Permitted Daily Exposure of the Androgen Receptor Antagonist Flutamide
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 279–289, https://doi.org/10.1093/toxsci/kfx135
INSULIN RESISTANCE AND NEUROTROPHIN SIGNALING IN MINIMAL HEPATIC ENCEPHALOPATHY
Insulin Resistance Disrupts the Interaction Between AKT and the NMDA Receptor and the Inactivation of the CaMKIV/CREB Pathway in Minimal Hepatic Encephalopathy
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 290–306, https://doi.org/10.1093/toxsci/kfx093
3-D TESTICULAR COCULTURE MODEL FOR TOXICITY SCREENING
From the Cover: An Animal-Free In Vitro Three-Dimensional Testicular Cell Coculture Model for Evaluating Male Reproductive Toxicants
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 307–326, https://doi.org/10.1093/toxsci/kfx139
CADMIUM INTERFERES WITH WOUND HEALING IN SKIN
Chronic Low-Dose Cadmium Exposure Impairs Cutaneous Wound Healing With Defective Early Inflammatory Responses After Skin Injury
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 327–338, https://doi.org/10.1093/toxsci/kfx137
PREDICTING LUNG INFLAMMATION AFTER EXPOSURE TO OXIDE NANOPARTICLES
A Mechanistic Model for Predicting Lung Inflammogenicity of Oxide Nanoparticles
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 339–353, https://doi.org/10.1093/toxsci/kfx136
DICHLOROACETIC ACID, METABOLIC DISRUPTION, AND CARCINOGENESIS
Metabolic Disruption Early in Life is Associated With Latent Carcinogenic Activity of Dichloroacetic Acid in Mice
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 354–365, https://doi.org/10.1093/toxsci/kfx146
DIFFERENTIAL EFFECTS OF MANGANESE AND ROTENONE IN iPSC-DERIVED DOPAMINE NEURONS
From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Human Dopamine Neurons
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 366–379, https://doi.org/10.1093/toxsci/kfx145
EVALUATION OF TRIPTOLIDE HEPATOTOXICITY IN ZEBRAFISH
Characterization of Triptolide-Induced Hepatotoxicity by Imaging and Transcriptomics in a Novel Zebrafish Model
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 380–391, https://doi.org/10.1093/toxsci/kfx144
ETHANOL DISRUPTION OF GLUCOSE UTILIZATION CONTRIBUTES TO CARDIOMYOPATHY
From the Cover: Alcohol Inhibition of the Enzymatic Activity of Glyceraldehyde 3-Phosphate Dehydrogenase Impairs Cardiac Glucose Utilization, Contributing to Alcoholic Cardiomyopathy
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 392–401, https://doi.org/10.1093/toxsci/kfx140
ROLE OF ER STRESS IN HEPATIC AMIODARONE TOXICITY
Hepatic Amiodarone Lipotoxicity Is Ameliorated by Genetic and Pharmacological Inhibition of Endoplasmatic Reticulum Stress
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 402–412, https://doi.org/10.1093/toxsci/kfx143
LACK OF HUMAN RELEVANCE FOR STYRENE TUMOROGENECITY
Editor’s Highlight: Complete Attenuation of Mouse Lung Cell Proliferation and Tumorigenicity in CYP2F2 Knockout and CYP2F1 Humanized Mice Exposed to Inhaled Styrene for up to 2 Years Supports a Lack of Human Relevance
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 413–421, https://doi.org/10.1093/toxsci/kfx141
NMR METABOLOMICS TO ASSESS SILVER NANOPARTICLE TOXICITY
From the Cover: Metabolism Modulation in Different Organs by Silver Nanoparticles: An NMR Metabolomics Study of a Mouse Model
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 422–435, https://doi.org/10.1093/toxsci/kfx142
ROLE OF PPARβ/δ AND PPARγ IN MELANOMA TUMORIGENICITY
Editor’s Highlight: PPARβ/δ and PPARγ Inhibit Melanoma Tumorigenicity by Modulating Inflammation and Apoptosis
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 436–448, https://doi.org/10.1093/toxsci/kfx147
SELENOMETHIONINE EFFECTS IN ADULT ZEBRAFISH
Cardiac and Metabolic Effects of Dietary Selenomethionine Exposure in Adult Zebrafish
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 449–460, https://doi.org/10.1093/toxsci/kfx149
SULFUR MUSTARD AND PULMONARY VASCULAR THROMBOSIS
Editor’s Highlight: Pulmonary Vascular Thrombosis in Rats Exposed to Inhaled Sulfur Mustard
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 461–469, https://doi.org/10.1093/toxsci/kfx151
DOXORUBICIN ALTERS RAT DNA METHYLOME
Editor’s Highlight: The Altered DNA Methylome of Chronic Doxorubicin Exposure in Sprague Dawley Rats
Toxicological Sciences, Volume 159, Issue 2, October 2017, Pages 470–479, https://doi.org/10.1093/toxsci/kfx150
CORRIGENDA
Atrazine and Breast Cancer: A Framework Assessment of the Toxicological and Epidemiological Evidence
Toxicological Sciences, Volume 159, Issue 2, October 2017, Page 480, https://doi.org/10.1093/toxsci/kfx148
Nonalcoholic Fatty Liver Disease Is a Susceptibility Factor for Perchloroethylene-Induced Liver Effects in Mice
Toxicological Sciences, Volume 159, Issue 2, October 2017, Page 481, https://doi.org/10.1093/toxsci/kfx158
