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Volume 152, Issue 1, July 2016
Look Inside ToxSci
From the Editor’s Desk, Editor’s Highlights
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 1–2, https://doi.org/10.1093/toxsci/kfw099
Contemporary Review: Assessing the Safety of CNS Administered Biologics
Safety Evaluation of CNS Administered Biologics—Study Design, Data Interpretation, and Translation to the Clinic
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 3–9, https://doi.org/10.1093/toxsci/kfw072
Forum: Systematic Reviews in Toxicology
The Emergence of Systematic Review in Toxicology
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 10–16, https://doi.org/10.1093/toxsci/kfw059
Ozone-Induced Effects on Glucocorticoid Signaling
Ozone Inhalation Provokes Glucocorticoid-Dependent and -Independent Effects on Inflammatory and Metabolic Pathways
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 17–28, https://doi.org/10.1093/toxsci/kfw061
Altered Arsenic Metabolism in Children
Arsenic Metabolism in Children Differs From That in Adults
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 29–39, https://doi.org/10.1093/toxsci/kfw060
Nrf2 Knockout Rats and Aflatoxin Toxicity
Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 40–52, https://doi.org/10.1093/toxsci/kfw065
Developmental Phthalate Exposure Disrupts Sertoli Cell Differentiation
Di(2-Ethylhexyl) Phthalate Exposure In Utero Damages Sertoli Cell Differentiation Via Disturbance of Sex Determination Pathway in Fetal and Postnatal Mice
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 53–61, https://doi.org/10.1093/toxsci/kfw063
MAPK/ERK Activation by Arsenite and Cadmium
Arsenite and Cadmium Activate MAPK/ERK via Membrane Estrogen Receptors and G-Protein Coupled Estrogen Receptor Signaling in Human Lung Adenocarcinoma Cells
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 62–71, https://doi.org/10.1093/toxsci/kfw064
Safety Profile of Antibody-Based Treatment of Asthma
Preclinical Safety Profile of a Depleting Antibody against CRTh2 for Asthma: Well Tolerated Despite Unexpected CRTh2 Expression on Vascular Pericytes in the Central Nervous System and Gastric Mucosa
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 72–84, https://doi.org/10.1093/toxsci/kfw067
Regulatory T Cells Mediate Toluene Diisocynatate Sensitization
A Role for Regulatory T Cells in a Murine Model of Epicutaneous Toluene Diisocyanate Sensitization
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 85–98, https://doi.org/10.1093/toxsci/kfw074
Function of Non-Myocyte Cells Derived from Stem Cell Cardiomyocyte Model
Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 99–112, https://doi.org/10.1093/toxsci/kfw069
Protective Role of Sirtuin 3 from Particulate Matter in Bronchial Epithelium
Sirtuin 3 Protects against Urban Particulate Matter-Induced Autophagy in Human Bronchial Epithelial Cells
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 113–127, https://doi.org/10.1093/toxsci/kfw073
Three-Dimensional Neurosphere System and Polyamidoamine
Effects of Polyamidoamine Dendrimers on a 3-D Neurosphere System Using Human Neural Progenitor Cells
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 128–144, https://doi.org/10.1093/toxsci/kfw068
Sperm Function Altered by Bisphenol a Exposure
Bisphenol A Impairs Mature Sperm Functions by a CatSper-Relevant Mechanism
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 145–154, https://doi.org/10.1093/toxsci/kfw070
Aryl Hydrocarbon Receptor-Mediated Inflammation and Cell Proliferation in Lung Cells Exposed to High Oxygen
Gene Expression Profiling Identifies Cell Proliferation and Inflammation as the Predominant Pathways Regulated by Aryl Hydrocarbon Receptor in Primary Human Fetal Lung Cells Exposed to Hyperoxia
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 155–168, https://doi.org/10.1093/toxsci/kfw071
Bisphenol a Exposure Causes DNA Damage in Ovaries
Bisphenol A-Induced Ovotoxicity Involves DNA Damage Induction to Which the Ovary Mounts a Protective Response Indicated by Increased Expression of Proteins Involved in DNA Repair and Xenobiotic Biotransformation
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 169–180, https://doi.org/10.1093/toxsci/kfw076
Metallothionein Polymorphisms in Diabetes and Renal Disease
Metallothionein MT2A A-5G Polymorphism as a Risk Factor for Chronic Kidney Disease and Diabetes: Cross-Sectional and Cohort Studies
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 181–193, https://doi.org/10.1093/toxsci/kfw080
Impaired Amyloid-Beta Clearance in Copper-Exposed Tissues
Copper Exposure Perturbs Brain Inflammatory Responses and Impairs Clearance of Amyloid-Beta
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 194–204, https://doi.org/10.1093/toxsci/kfw081
Urinary microRNA Biomarkers of Acute Kidney Injury
Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 205–213, https://doi.org/10.1093/toxsci/kfw077
Upcyte Hepatocytes for Toxicity Testing
Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 214–229, https://doi.org/10.1093/toxsci/kfw078
Integration of PBPK and AOPs for Environmental Hazard Assessment
Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 230–243, https://doi.org/10.1093/toxsci/kfw082
Perinatal Butylparaben Perturbs Endocrine Function
Multiple Endocrine Disrupting Effects in Rats Perinatally Exposed to Butylparaben
Toxicological Sciences, Volume 152, Issue 1, July 2016, Pages 244–256, https://doi.org/10.1093/toxsci/kfw079
COVER
Cover
Toxicological Sciences, Volume 152, Issue 1, July 2016, Page i1, https://doi.org/10.1093/toxsci/kfv286
STANDING MATERIAL
Editorial Board
Toxicological Sciences, Volume 152, Issue 1, July 2016, Page i2, https://doi.org/10.1093/toxsci/kfv287
Subscriptions
Toxicological Sciences, Volume 152, Issue 1, July 2016, Page i3, https://doi.org/10.1093/toxsci/kfv288
Table of Contents
Toxicological Sciences, Volume 152, Issue 1, July 2016, Page i4, https://doi.org/10.1093/toxsci/kfv289
