Volume 150, Issue 2, April 2016

Look Inside ToxSci

From the Editor’s Desk, Editor’s Highlights

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 257–258, https://doi.org/10.1093/toxsci/kfw043

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Editorial

Society of Toxicology Board of Publications Best Paper Award for 2016

Gary W. Miller

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 259–260, https://doi.org/10.1093/toxsci/kfw036

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Contemporary Review: Biological Network of Hepatic Steatosis

Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis

Michelle M. Angrish and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 261–268, https://doi.org/10.1093/toxsci/kfw018

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Chlorotriazine Risk Assessment in Drinking Water

PBPK-Based Probabilistic Risk Assessment for Total Chlorotriazines in Drinking Water

Charles B. Breckenridge and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 269–282, https://doi.org/10.1093/toxsci/kfw013

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The Mycotoxin Beauvericin Alters Neurotransmission

Beauvericin Inhibits Neuromuscular Transmission and Skeletal Muscle Contractility in Mouse Hemidiaphragm Preparation

Monika Cecilija Žužek and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 283–291, https://doi.org/10.1093/toxsci/kfv326

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Metal Analysis in Alzheimer’s Disease

Comparison of Metal Levels between Postmortem Brain and Ventricular Fluid in Alzheimer’s Disease and Nondemented Elderly Controls

Steven T. Szabo and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 292–300, https://doi.org/10.1093/toxsci/kfv325

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Alkenylbenzenes and DNA Damage

Structure-Activity Relationships for DNA Damage by Alkenylbenzenes in Turkey Egg Fetal Liver

Tetyana Kobets and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 301–311, https://doi.org/10.1093/toxsci/kfv322

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Adrenal Gland Function and Pulmonary Response to Ozone

Acute Ozone-Induced Pulmonary and Systemic Metabolic Effects Are Diminished in Adrenalectomized Rats

Desinia B. Miller and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 312–322, https://doi.org/10.1093/toxsci/kfv331

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Toxicant Screen for Altered Steroid Synthesis

High-Throughput Screening of Chemical Effects on Steroidogenesis Using H295R Human Adrenocortical Carcinoma Cells

Agnes L. Karmaus and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 323–332, https://doi.org/10.1093/toxsci/kfw002

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Tungsten and Mesenchymal Stromal Cell Differentiation

Tungsten Promotes Sex-Specific Adipogenesis in the Bone by Altering Differentiation of Bone Marrow-Resident Mesenchymal Stromal Cells

Alicia M. Bolt and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 333–346, https://doi.org/10.1093/toxsci/kfw008

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Altered Brain Neurogenesis and Manganese Exposure

Aberrant Adult Neurogenesis in the Subventricular Zone-Rostral Migratory Stream-Olfactory Bulb System Following Subchronic Manganese Exposure

Sherleen Fu and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 347–368, https://doi.org/10.1093/toxsci/kfw007

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MRI Analysis of Brains of Welders

Increased R2* in the Caudate Nucleus of Asymptomatic Welders

Eun-Young Lee and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 369–377, https://doi.org/10.1093/toxsci/kfw003

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High Density Lipoprotein Mimetic and Multiorgan Inflammation

Immunogenicity, Inflammation, and Lipid Accumulation in Cynomolgus Monkeys Infused with a Lipidated Tetranectin-ApoA-I Fusion Protein

Franziska Regenass-Lechner and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 378–389, https://doi.org/10.1093/toxsci/kfw004

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Metabolomic Biomarkers of Hepatotoxicity

A Systematic Strategy for Screening and Application of Specific Biomarkers in Hepatotoxicity Using Metabolomics Combined With ROC Curves and SVMs

Yubo Li and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 390–399, https://doi.org/10.1093/toxsci/kfw001

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Doxorubicin-Induced Cardiomyocyte Toxicty and Transcriptional Networks

A PGC-1α-Mediated Transcriptional Network Maintains Mitochondrial Redox and Bioenergetic Homeostasis against Doxorubicin-Induced Toxicity in Human Cardiomyocytes: Implementation of TT21C

Haitao Yuan and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 400–417, https://doi.org/10.1093/toxsci/kfw006

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Effects of Metal Oxide Nanoparticles of Airway Epithelium

Toxicological Assessment of CoO and La₂O₃ Metal Oxide Nanoparticles in Human Small Airway Epithelial Cells

Jennifer D. Sisler and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 418–428, https://doi.org/10.1093/toxsci/kfw005

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Developmental TCDD Exposure and Urinary Tract Function

In Utero and Lactational TCDD Exposure Increases Susceptibility to Lower Urinary Tract Dysfunction in Adulthood

William A. Ricke and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 429–440, https://doi.org/10.1093/toxsci/kfw009

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Pharmacokinetic Modeling of Atrazine and Metabolites

PBPK Model for Atrazine and Its Chlorotriazine Metabolites in Rat and Human

Jerry L. Campbell and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 441–453, https://doi.org/10.1093/toxsci/kfw014

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Zinc Oxide Nanoparticle and Integrity of DNA and Cytoskeleton

Zinc-Oxide Nanoparticles Exhibit Genotoxic, Clastogenic, Cytotoxic and Actin Depolymerization Effects by Inducing Oxidative Stress Responses in Macrophages and Adult Mice

Rashmirekha Pati and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 454–472, https://doi.org/10.1093/toxsci/kfw010

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Silver Nanoparticles, Autophagy, and Inflammation

Silver Nanoparticle-Induced Autophagic-Lysosomal Disruption and NLRP3-Inflammasome Activation in HepG2 Cells Is Size-Dependent

Anurag R. Mishra and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 473–487, https://doi.org/10.1093/toxsci/kfw011

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Carbon Nanotube and Vascular Function

MMP-9-Dependent Serum-Borne Bioactivity Caused by Multiwalled Carbon Nanotube Exposure Induces Vascular Dysfunction via the CD36 Scavenger Receptor

Mario Aragon and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 488–498, https://doi.org/10.1093/toxsci/kfw015

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OP Flame Retardants and Endocrine Disruption

Organophosphate Flame Retardants Act as Endocrine-Disrupting Chemicals in MA-10 Mouse Tumor Leydig Cells

Gauthier Schang and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 499–509, https://doi.org/10.1093/toxsci/kfw012

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Computational Approach to Develop Fatty Liver AOPs

Integrating Publicly Available Data to Generate Computationally Predicted Adverse Outcome Pathways for Fatty Liver

Shannon M. Bell and others

Toxicological Sciences, Volume 150, Issue 2, April 2016, Pages 510–520, https://doi.org/10.1093/toxsci/kfw017

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COVER

Cover

Toxicological Sciences, Volume 150, Issue 2, April 2016, Page i1, https://doi.org/10.1093/toxsci/kfv274

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STANDING MATERIAL

Editorial Board

Toxicological Sciences, Volume 150, Issue 2, April 2016, Page i2, https://doi.org/10.1093/toxsci/kfv275

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Subscriptions

Toxicological Sciences, Volume 150, Issue 2, April 2016, Page i3, https://doi.org/10.1093/toxsci/kfv276

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Table of Contents

Toxicological Sciences, Volume 150, Issue 2, April 2016, Page i4, https://doi.org/10.1093/toxsci/kfv277

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