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Call for Papers: Cord Blood

STEM CELLS Translational Medicine®, the official journal of the Cord Blood Association (CBA), is a monthly, peer-reviewed, open access journal. 

STEM CELLS Translational Medicine works to advance the clinical utilization of stem cell molecular and cellular biology. The journal encourages original research articles and concise reviews describing laboratory investigations of stem cells, including their characterization and manipulation, and the translation of their clinical aspects from the bench to patient care. 

Under the leadership of section co-editors, Joanne Kurtzberg, MD, and Karen K. Ballen, MD, STEM CELLS Translational Medicine encourages original research and concise review article submissions focused on: 

  • Umbilical cord blood and tissue-based therapies
  • Accessory cell populations
  • Modulation of endogenous cell and tissue repair
  • Cord blood and cord tissue banking
  • Malignant and non-malignant diseases treated by cord blood transplantation
  • Cord blood and cord tissue in regenerative medicine

Please join us in our missions to help foster breakthroughs in stem cell therapies and regenerative medicine by submitting your article today. Learn more about our instructions to authors here.

For more reasons to publish with STEM CELLS Translational Medicine, head to this page.

Cord Blood Articles

Research Article
Human umbilical cord mesenchymal stem cell-derived exosomes promote osteogenesis in glucocorticoid-induced osteoporosis through PI3K/AKT signaling pathway-mediated ferroptosis inhibition
Zhi-Meng Zhao and others
Stem Cells Translational Medicine, Volume 14, Issue 3, March 2025, szae096, https://doi.org/10.1093/stcltm/szae096
Glucocorticoid-induced osteoporosis (GIOP), the most common cause of secondary osteoporosis, is characterized by significant bone loss, decreased bone quality, and increased fracture risk. The current treatments for GIOP have several drawbacks. Exosomes are vital for cellular processes. However, ...
Research Article
A Randomized, Placebo-Controlled, Phase II Trial of Intravenous Allogeneic Non-HLA Matched, Unrelated Donor, Cord Blood Infusion for Ischemic Stroke
Daniel T Laskowitz and others
Stem Cells Translational Medicine, Volume 13, Issue 2, February 2024, Pages 125–136, https://doi.org/10.1093/stcltm/szad080
Stroke remains a leading cause of death and disability in the US, and time-limited reperfusion strategies remain the only approved treatment options. To address this unmet clinical need, we conducted a phase II randomized clinical trial to determine whether intravenous infusion of banked, non-HLA ...
Research Article
Long-Term Stability of Cord Blood Units After 29 Years of Cryopreservation: Follow-Up Data From the José Carreras Cord Blood Bank
Stefanie Liedtke and others
Stem Cells Translational Medicine, Volume 13, Issue 1, January 2024, Pages 30–42, https://doi.org/10.1093/stcltm/szad071
The José Carreras Cord Blood Bank (CBB) located in Düsseldorf as of today stores 21 215 active cryopreserved cord blood units (CBUs) applicable as a source for hematopoietic stem cell (HSC) transplantation. Since the success of transplantation outcomes is mainly dependent on the cord blood quality, ...
Research Article
The Antioxidant TEMPOL Protects Human Hematopoietic Stem Cells From Culture-Mediated Loss of Functions
Elia Henry and others
Stem Cells Translational Medicine, Volume 12, Issue 10, October 2023, Pages 676–688, https://doi.org/10.1093/stcltm/szad049
In a steady state, hematopoietic stem cells (HSC) exhibit very low levels of reactive oxygen species (ROS). Upon stress, HSC get activated and enter into proliferation and differentiation process to ensure blood cell regeneration. Once activated, their levels of ROS increase, as messengers to ...
Research Article
Unrelated Donor Cord Blood Transplantation in Children: Lessons Learned Over 3 Decades
Joanne Kurtzberg and others
Stem Cells Translational Medicine, Volume 12, Issue 1, January 2023, Pages 26–38, https://doi.org/10.1093/stcltm/szac079
Four decades ago, Broxmeyer et al. demonstrated that umbilical cord blood (CB) contained hematopoietic stem cells (HSC) and hypothesized that CB could be used as a source of donor HSC for rescue of myeloablated bone marrow. In 1988, Gluckman et al. reported the first successful matched sibling cord ...
Research Article
Identification and Re-consent of Existing Cord Blood Donors for Creation of Induced Pluripotent Stem Cell Lines for Potential Clinical Applications
Keren M Abberton and others
Stem Cells Translational Medicine, Volume 11, Issue 10, October 2022, Pages 1052–1060, https://doi.org/10.1093/stcltm/szac060
We aim to create a bank of clinical grade cord blood-derived induced pluripotent stem cell lines in order to facilitate clinical research leading to the development of new cellular therapies. Here we present a clear pathway toward the creation of such a resource, within a strong quality framework, ...
Research Article
Augmented Production of Platelets From Cord Blood With Euchromatic Histone Lysine Methyltransferase Inhibition
Yiying Liu and others
Stem Cells Translational Medicine, Volume 11, Issue 9, September 2022, Pages 946–958, https://doi.org/10.1093/stcltm/szac048
Cord blood hematopoietic stem/progenitor cells (CB-HSPCs) have emerged as a promising supply for functional platelets to potentially alleviate the increasing demand for platelet transfusions, but the clinical application has been limited by the undefined molecular mechanism and insufficient ...
Research Article
Contamination Rate of Cryopreserved Umbilical Cord Blood Is Inversely Correlated with Volume of Sample Collected and Is also Dependent on Delivery Mode
Susanne Reuther and others
Stem Cells Translational Medicine, Volume 11, Issue 6, June 2022, Pages 604–612, https://doi.org/10.1093/stcltm/szac020
Cord blood (CB) collected at birth has become a valuable stem cell source for hematopoietic stem cell transplantation (HSCT). However, the collection of umbilical cord blood always bears a risk of microbiological contamination, both in vaginal birth and in cesarean section. A total of 10 054 ...
Brief Report
Transient Inhibition of the JNK Pathway Promotes Human Hematopoietic Stem Cell Quiescence and Engraftment
Huangfan Xie and others
Stem Cells Translational Medicine, Volume 11, Issue 6, June 2022, Pages 597–603, https://doi.org/10.1093/stcltm/szac019
The widespread clinical application of cord blood (CB) for hematopoietic stem cell (HSC) transplantation is limited mainly by the inadequate number of hematopoietic stem and progenitor cells (HSPCs) in single CB units, which results in unsuccessful or delayed engraftment in recipients. The ...
Research Article
Transcriptional and functional characterization of neonatal circulating Innate Lymphoid Cells
Sabrina Bianca Bennstein and others
Stem Cells Translational Medicine, Volume 10, Issue 6, June 2021, Pages 867–882, https://doi.org/10.1002/sctm.20-0300
Innate lymphoid cells (ILCs), comprising ILC1, 2, and 3 subpopulations, play unique roles in maintaining microbiome homeostasis, mucosal tissue integrity, and control of inflammation. So far, their characterization is dominantly based on tissue-resident ILCs, whereas little information is available ...
Rapid Communication
Worldwide survey on key indicators for public cord blood banking technologies: By the World Marrow Donor Association Cord Blood Working Group
Monique Jöris and others
Stem Cells Translational Medicine, Volume 10, Issue 2, February 2021, Pages 222–229, https://doi.org/10.1002/sctm.20-0246
The Cord Blood Working Group of the World Marrow Donor Association created a survey for cord blood banks (CBBs) aimed to identify and understand the main technical procedures currently used by public CBBs worldwide regarding cord blood units (CBUs) available for unrelated hematopoietic stem cell ...
Research Article
Human cord blood-derived regulatory T-cell therapy modulates the central and peripheral immune response after traumatic brain injury
Henry W. Caplan and others
Stem Cells Translational Medicine, Volume 9, Issue 8, August 2020, Pages 903–916, https://doi.org/10.1002/sctm.19-0444
Traumatic brain injury (TBI) causes a profound inflammatory response within the central nervous system and peripheral immune system, which contributes to secondary brain injury and further morbidity and mortality. Preclinical investigations have demonstrated that treatments that downregulate ...
Research Article
Autologous cord blood cell infusion in preterm neonates safely reduces respiratory support duration and potentially preterm complications
Zhuxiao Ren and others
Stem Cells Translational Medicine, Volume 9, Issue 2, February 2020, Pages 169–176, https://doi.org/10.1002/sctm.19-0106
Preterm birth and its complications are the leading cause of neonatal death. The main underlying pathological mechanisms for preterm complications are disruption of the normal maturation processes within the target tissues, interrupted by premature birth. Cord blood, as a new and convenient source ...
Research Article
Human Cord Blood-Derived Unrestricted Somatic Stem Cell Infusion Improves Neurobehavioral Outcome in a Rabbit Model of Intraventricular Hemorrhage
Govindaiah Vinukonda and others
Stem Cells Translational Medicine, Volume 8, Issue 11, November 2019, Pages 1157–1169, https://doi.org/10.1002/sctm.19-0082
Intraventricular hemorrhage (IVH) is a severe complication of preterm birth, which leads to hydrocephalus, cerebral palsy, and mental retardation. There are no available therapies to cure IVH, and standard treatment is supportive care. Unrestricted somatic stem cells (USSCs) from human cord blood ...
Research Article
Model Criteria for Regulation of Cord Blood Banks and Cord Blood Banking: Adopted by the Cord Blood Association, Board of Directors, January 29, 2019: Adopted by the Cord Blood Association, Board of Directors, January 29, 2019
Stem Cells Translational Medicine, Volume 8, Issue 4, April 2019, Pages 340–343, https://doi.org/10.1002/sctm.cbmc
A substantial volume of the umbilical cord blood used in clinical therapies around the world is transported between countries. The unit of cord blood that is the best biological match for a particular patient frequently has been collected, processed and stored in another country. Unfortunately, the ...
Research Article
White Matter Tract Changes Associated with Clinical Improvement in an Open-Label Trial Assessing Autologous Umbilical Cord Blood for Treatment of Young Children with Autism
Kimberly L. H. Carpenter and others
Stem Cells Translational Medicine, Volume 8, Issue 2, February 2019, Pages 138–147, https://doi.org/10.1002/sctm.18-0251
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder characterized by social communication deficits and the presence of restricted interests and repetitive behaviors. We have previously reported significant improvements in behavior, including increased social functioning, ...
Research Article
Electrophysiological Biomarkers Predict Clinical Improvement in an Open-Label Trial Assessing Efficacy of Autologous Umbilical Cord Blood for Treatment of Autism
Michael Murias and others
Stem Cells Translational Medicine, Volume 7, Issue 11, November 2018, Pages 783–791, https://doi.org/10.1002/sctm.18-0090
This study was a phase I, single-center, and open-label trial of a single intravenous infusion of autologous umbilical cord blood in young children with autism spectrum disorder (ASD). Twenty-five children between the ages of 2 and 6 with a confirmed diagnosis of ASD and a qualified banked ...
Research Article
Factors Influencing the Umbilical Cord Blood Stem Cell Industry: An Evolving Treatment Landscape
Carla Dessels and others
Stem Cells Translational Medicine, Volume 7, Issue 9, September 2018, Pages 643–650, https://doi.org/10.1002/sctm.17-0244
Hematopoietic stem cell transplantation (HSCT) is common practice today for life threatening malignant and non-malignant diseases of the blood and immune systems. Umbilical cord blood (UCB) is rich in hematopoietic stem cells (HSCs) and is an attractive alternative to harvesting HSCs from bone ...
Research Article
Allogeneic Umbilical Cord Blood Infusion for Adults with Ischemic Stroke: Clinical Outcomes from a Phase I Safety Study
Daniel T. Laskowitz and others
Stem Cells Translational Medicine, Volume 7, Issue 7, July 2018, Pages 521–529, https://doi.org/10.1002/sctm.18-0008
Stroke is a major cause of death and long-term disability, affecting one in six people worldwide. The only currently available approved pharmacological treatment for ischemic stroke is tissue plasminogen activator; however, relatively few patients are eligible for this therapy. We hypothesized that ...
Research Article
Functional Integrity and Gene Expression Profiles of Human Cord Blood-Derived Hematopoietic Stem and Progenitor Cells Generated In Vitro
Roberto Dircio-Maldonado and others
Stem Cells Translational Medicine, Volume 7, Issue 8, August 2018, Pages 602–614, https://doi.org/10.1002/sctm.18-0013
To date, different experimental strategies have been developed for the ex vivo expansion of human hematopoietic stem (HSCs) and progenitor (HPCs) cells. This has resulted in significant advances on the use of such expanded cells in transplantation settings. To this day, however, it is still unclear ...
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