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Sexual dysfunctions in patients with well-compensated chronic liver disease: role of etiology, Mediterranean diet and quality of life in an observational cross-sectional study
Lorenzo Romano and others
Background Sexual dysfunctions (SD) are highly prevalent in Chronic Liver Diseases (CLD). Whether Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) carries a higher risk of SD is unknown as is the role of dietary patterns or quality of Life (QoL). Aim to assess (1) prevalence of SD ...
Methods, practices, and complications related to the use of artificial penile nodules within the French Guiana penitentiary
Jeremy Vergez and others
Background Artificial penile nodules (APNs) are small, handmade objects inserted under the penile skin, a practice deeply rooted in the prison environment of French Guiana, raising significant concerns related to sexual health, including complications and an increased risk of sexually transmitted ...
AI-assisted transcription of YouTube videos on penile enlargement: analysis of their text quality and readability
Mehmet Fatih Şahin and others
Background Patients dealing with sensitive issues like penile enlargement (PE) might benefit from YouTube videos. Therefore, it is essential that the textual content of these videos is clear, trustworthy, and of high quality. Aim Are the AI-assisted acquired texts’ qualities and comprehensibilities ...
Letter to the Editor on “The associations among platelet count, mean platelet volume, and erectile dysfunction: an observational and Mendelian randomization study”
Yuekun Fang and others
To the Editor, We read with great interest the article titled “ The associations among platelet count, mean platelet volume, and erectile dysfunction: an observational and Mendelian randomization study, ” which provides valuable insights into the relationship between platelet parameters and ...
Response to Letter to the Editor on “The associations among platelet count, mean platelet volume, and erectile dysfunction: an observational and Mendelian randomization study”
Jingxuan Peng and others
To the Editor, We are pleased to see that our article has received recognition and has sparked significant discussions. 1 We appreciate their interest in our work and their efforts to further strengthen the scientific discourse in this area. To further foster this meaningful exchange, we will ...
Letter to the Editor on “Association of total testosterone levels with cardiometabolic diseases in men with erectile dysfunction”
Scott Selinger and Gregory R Thoreson
We appreciate the work of Chen et al. 1 in furthering the linkage between low testosterone and a myriad of comorbidities with increased cardiovascular disease. There are several clarifying points on their work we would like to add. First, this information should serve to remind the medical and ...
Menopause is associated with a decrease in sexual function among women with endometriosis
Alexandre Vallée and others
Background Menopause-related endocrinological shifts are linked to sexual dysfunction, and women with endometriosis exhibit lower Female Sexual Function Index (FSFI) scores, indicating impaired sexual well-being. Aim To assess the impact of menopause on sexual function in women with endometriosis. ...
Letter to the editor on “No bidirectional association between serum 25-hydroxyvitamin D and erectile dysfunction: Mendelian randomization and genetic association studies”
Xingcheng Zhu and others
None declated. None declared. Xingcheng Zhu, Junxian Zhao, Mengjun Tang, Shi Fu and Jieming Zuo contributed equally. In conclusion, while Liu et al.’s study provides a solid foundation for understanding the potential causal relationship between 25(OH)D and ED, addressing these methodological ...
Icariin inhibits hyperglycemia-induced cell death in penile cavernous tissue and improves erectile function in type 1 diabetic rats
Haowei Yang and others
Background Hyperglycemia can cause endothelial cell (EC) and smooth muscle cell (SMC) death in the penile cavernous tissue of rats and lead to erectile dysfunction (ED). Objectives To investigate the proportions of apoptotic, pyroptotic, and ferroptotic cells among ECs and SMCs in the penile ...
Mendelian randomization analyses reveal causal relationships between chronic psychological stress and risk of erectile dysfunction
Wei Wang and others
Background The association between psychological stress and erectile dysfunction (ED) has been reported, but the causality of different types of stressors on ED is poorly understood. Aim This study aims to investigate the causal relationship between various forms of psychological stress and ED ...
Association between C-reactive protein-triglyceride glucose index and testosterone levels among adult men: analyses of NHANES 2015–2016 data
Bo Zhang and others
Background The C-reactive protein-triglyceride glucose index (CTI) is a recently introduced index designed to simultaneously assess inflammation (via CRP) and insulin resistance (via the triglyceride-glucose index, TyG), both of which are recognized risk factors for declining testosterone levels in ...
Sexual satisfaction and function (SatisFunction) survey post-vaginoplasty for transgender and gender diverse individuals: preliminary development and content validity for future clinical use
Amine Sahmoud and others
Background Transgender and gender diverse individuals (TGDIs) are people whose gender identity is not in line with their sex assigned at birth, but current surveys used for cisgender patients addressing sexual satisfaction and function (SFS) do not fit the needs of this unique population. Aim The ...
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