... that the present cratonic roots are notably denser than the ambient mantle, with the compositional buoyancy offsetting only one-fifth of the negative thermal buoyancy. In addition, the presence of a weak mid-lithospheric discontinuity could decouple the upper and lower lithosphere upon perturbation, allowing...

.... Conclusions Older adults with prior head injury had worse physical functioning and greater frailty at baseline and were more likely to become frail and walk slower over time, compared to individuals without head injury. Aging Gait speed Physical decline Traumatic brain injury Weakness The age-adjusted...

... of this report ( Suppl. Materials ). Abstract Objective The objective of this study was to evaluate the impact of intensive care unit (ICU)-acquired weakness (ICUAW) on the functional independence of patients hospitalized for coronavirus disease 2019 (COVID-19) over 6 months after ICU discharge. Methods...

... not been causally linked to muscle weakness per se, it seems likely they could affect functional mobility as they likely result in less automaticity of motor tasks and require a greater engagement of attention and cognitive resources. There is, however, more direct evidence linking reduced cortical...

... and increased need for physical therapy. COVID-19 Critical Illness Early Ambulation Early Mobilization Muscle Weakness Physical Therapy Specialty Physiotherapy Rehabilitation The coronavirus disease of 2019 (COVID-19) pandemic inflicted a substantial burden on health care systems around the world...

... ]. Muscle lengths and volumes were calculating using MATLAB. Abstract Context Children with X-linked hypophosphatemic (XLH) rickets have muscle weakness that severely impairs their function. Intermuscular and intramuscular adipose tissue (IMAT and intraMAT, respectively) may contribute to this muscle...

... of a hypogonadal male reveals previously unrecognized ataxia, movement disorder, muscle weakness, tremor, or seizures, leading to a syndromic diagnosis. Androgen deficiency in patients with neurological diseases may aggravate muscle weakness and fatigue and predispose patients to osteoporosis and obesity...

... Muscle Weakness Neuromuscular Diseases Reproducibility of Results Neuromuscular disorders (NMDs) are a heterogeneous group of acquired and genetic diseases that may encompass all levels of dysfunction of the peripheral nervous system—that is, the anterior horn cells, the peripheral nerve...

... investigated mechanisms by which microRNA (miR)-181a orchestrates mitochondrial dysfunction and inflammation in a rat model of intensive care unit-acquired weakness (ICU-AW). Expression of miR-181a and insulin-like growth factor binding protein 5 (IGFBP5) was detected...

... Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Graphical Abstract Graphical Abstract Respiratory muscle weakness Frailty status Cardiovascular disease Maximal inspiratory pressure Fried criteria...

...:https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Objective The primary objective of this study was to identify the occurrence and factors associated with intensive care unit (ICU)-acquired weakness (ICUAW) in patients with COVID-19. Secondarily, we...

... Hiromura; Yusuke Miwa; Hiroshi Nakajima; Masataka Kuwana; Yasuhiko Nishioka; Akio Morinobu; Hideto Kameda; Hitoshi Kohsaka PM/DM are autoimmune diseases that affect skeletal muscle. Patients suffer from muscle weakness, decreased muscle endurance and restriction of activities of daily life. Glucocorticoids...

... on days 4–7. This trial was registered at https://www.umin.ac.jp as UMIN000041276. PICS post-intensive care syndrome ICU-AW intensive care unit acquired weakness COVID-19 nutrition protein energy Nutrition therapy is one of the important components of critical care. Although adequate nutrition...

... hyperproduction in a feed-forward autocrine/paracrine loop that not only drives the pathobiology of TIO, but may also be implicated in tumorigenesis [ 15 ]. The onset of TIO is subacute in most cases, and initial symptoms may include musculoskeletal pain, fatigue, and proximal muscle weakness and/or atrophy...

... displaces low muscle mass as a defining feature of sarcopenia. The change stems from growing evidence that muscle weakness is a better predictor of adverse health outcomes (eg, mobility limitations) than muscle mass. This evidence accompanies an emerging recognition that central neural mechanisms...

... bone, muscle weakness, and characteristic fracture pattern, often referred to as pseudofractures, involving ribs, scapulae, pubic rami, proximal femurs, and codfish type vertebrae. The goal of therapy of vitamin D deficiency osteomalacia is to alleviate symptoms, promote fracture healing, restore bone...

... early preventative strategies for physical frailty and sarcopenia. Vascular Endothelial Dysfunction Frailty Sarcopenia Muscle Weakness Ageing Inflammation Older People Physical frailty is associated with poor health outcomes, high healthcare utilisation and economic cost. Frailty is linked...

... in children with cerebral palsy compared with children with TD. ^12–15 Whether muscle strength weakness in the more-affected UE is the cause of this reduced performance is unclear, and one should keep in mind that these differences can also be attributed to problems with speed and/or coordination...

... correlation with abductor peak torque, only LS and TG time were able to discriminate reduced abductor muscle strength with low accuracy (area under the curve was between 0.5 and 0.7). However, the combination of LS and TG time increased post-test probability from 47% (prevalence of weakness in the population...

..., balance, and reaching. In individuals with DMD, equilibrium/righting reactions and dynamic postural control mechanisms that rely on trunk musculature may contribute to decreased balance. ^{38 , 39} In other populations with weak trunk muscles, individuals generally attempt...