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Keywords: uveitis
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Journal Article
The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs
Sizheng Steven Zhao and others
in
Rheumatology
Rheumatology, keaf089, https://doi.org/10.1093/rheumatology/keaf089
Published: 09 April 2025
...-musculoskeletal manifestations (EMMs) such as acute anterior uveitis, psoriasis and IBD. Symptoms of axSpA typically begin in early adulthood but diagnosis can often take several years [ 2 ]. Chronic inflammatory pain and stiffness are well recognized as having adverse effects on quality of life, social...
Journal Article
Executive Summary: The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs
Sizheng Steven Zhao and others
in
Rheumatology
Rheumatology, keaf090, https://doi.org/10.1093/rheumatology/keaf090
Published: 09 April 2025
.... 23 01 2025 23 01 2025 Axial spondyloarthritis (axSpA) is a chronic inflammatory condition that predominantly affects the spine and sacroiliac joints [ 1 ]. It can also involve peripheral joints and entheses, and extra-musculoskeletal manifestations (EMMs) such as acute anterior uveitis...
Journal Article
Unusual systemic conditions in a patient with giant cell arteritis
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Khalid El-Jack and others
Modern Rheumatology Case Reports, rxaf014, https://doi.org/10.1093/mrcr/rxaf014
Published: 14 March 2025
... manifestations typically include headache, jaw pain, fever, and fatigue. However, unusual manifestations of the disease have been reported, including pulmonary nodules, uveitis, pericarditis, and stroke. We report a case of biopsy-confirmed giant cell arteritis in a patient found to have renal cell carcinoma...
Journal Article
Protective Effects of Recombinant Zoster Vaccine and Antiviral Therapy Against Cardiovascular Disease Following Herpes Zoster Infection
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Xinyi Xu and others
The Journal of Infectious Diseases, jiaf105, https://doi.org/10.1093/infdis/jiaf105
Published: 01 March 2025
... disease in the year following a herpes zoster infection. recombinant zoster vaccine herpes zoster cardiovascular disease uveitis antiviral treatment Herpes zoster (HZ) is a viral syndrome resulting from the reactivation of varicella zoster virus (VZV), typically occurring in adults aged ≥50 years...
Journal Article
Posterior localized nodular scleritis mimicking malignancy, a case report and clinical approach
Mehrdad Motamed Shariati and others
Oxford Medical Case Reports, Volume 2024, Issue 11, November 2024, omae146, https://doi.org/10.1093/omcr/omae146
Published: 25 November 2024
... diagnosis of nodular posterior scleritis oral prednisolone 50 mg/Kg was started. Conclusion : Posterior scleritis is an uncommon inflammatory condition that could be misdiagnosed with choroidal tumors, posterior uveitis, and orbital inflammation. posterior scleritis choroidal tumors multimodal imaging...
Journal Article
EDITOR'S CHOICE
State-of-the-Art Review: Ocular Infections
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Miriam B Barshak and others
Clinical Infectious Diseases, Volume 79, Issue 5, 15 November 2024, Pages e48–e64, https://doi.org/10.1093/cid/ciae433
Published: 19 November 2024
...+ cataract as before No white blood cells; ie, the inflammation is confined to the anterior segment of the eye Comment: The exam shows that there is now an anterior uveitis; topical corticosteroids will be added while continuing the oral valacyclovir. The fundus exam is normal Acute infectious...
Journal Article
Ocular outcomes of toxoplasmosis in the Amazon–Cerrado transition zone, Brazil: a population-based study
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Ana Paula Salamoni and others
Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 119, Issue 2, February 2025, Pages 113–117, https://doi.org/10.1093/trstmh/trae078
Published: 14 November 2024
... for personalized clinical care and for shaping national guidelines for managing toxoplasmosis. eye manifestation ocular toxoplasmosis visual acuity and uveitis National Council for Scientific and Technological Development 10.13039/501100003593 308899/2022-9 Coordination of Superior Level Staff...
Journal Article
Adalimumab-induced CNS demyelination in a patient with multiple pre-existing autoimmune diseases: Treatment contemplation
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Sepehr Khosravi and others
Modern Rheumatology Case Reports, Volume 9, Issue 1, January 2025, Pages 75–78, https://doi.org/10.1093/mrcr/rxae069
Published: 07 November 2024
... a previous medical history of intermediate uveitis and rheumatoid arthritis. Anti-TNF-α treatment was initiated with adalimumab 2 years before this visit. Magenetic resonance imaging showed numerous T2-hyperintense lesions in bilateral periventricular, juxtacortical, and subcortical areas, which were absent...
Journal Article
Prevalence and incidence of uveitis in patients with spondyloarthritis: the impact of the biologics era. Data from the international ASAS-COMOSPA study
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Hernán Maldonado-Ficco and others
in
Rheumatology
Rheumatology, Volume 64, Issue 5, May 2025, Pages 2618–2624, https://doi.org/10.1093/rheumatology/keae536
Published: 03 October 2024
... Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Objectives Uveitis is a common extra-musculoskeletal manifestation in SpA. The aim of this study was to analyze the prevalence of uveitis in SpA patients, and its association with geographical areas...
Journal Article
Epidemiology and Clinical Characteristics of Ocular Tuberculosis in the United States, 1993–2019
Thomas D Filardo and others
Open Forum Infectious Diseases, Volume 11, Issue 9, September 2024, ofae476, https://doi.org/10.1093/ofid/ofae476
Published: 22 August 2024
... tuberculosis surveillance infectious uveitis More than 30% of patients diagnosed with tuberculosis (TB) in the United States in 2019 had extrapulmonary disease, including two-thirds without pulmonary involvement [ 1 ]. TB can affect every organ in the body, including the eye, where it most often presents...
Journal Article
The Prevalence and Characteristics of Inflammatory Bowel Disease-related Ocular Involvement in Children
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Amir Ben-Tov and others
Inflammatory Bowel Diseases, izae160, https://doi.org/10.1093/ibd/izae160
Published: 24 July 2024
... = .005). An analysis of the subcohort of patients with uveitis only yielded similar results (data not shown). Table 2. Multivariate analysis and adjusted odds-ratio among children diagnosed with IBD during childhood with and without ocular involvement. Covariate OR 95% CI P...
Journal Article
Ocular Syphilis in Patients With Nonreactive Rapid Plasma Reagin and Positive Treponemal Serologies: A Retrospective Observational Cohort Study
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Amir M Mohareb and others
Clinical Infectious Diseases, ciae354, https://doi.org/10.1093/cid/ciae354
Published: 02 July 2024
... likely to be living with human immunodeficiency virus (49%, P < .001). People with nonreactive and low-titer RPR were less likely than those with high-titer RPR to have posterior uveitis/panuveitis (32% and 29% vs 75%, P < .001) or abnormal cerebrospinal fluid (26% and 35% vs 75...
Journal Article
TIGIT stimulation suppresses autoimmune uveitis by inhibiting Th17 cell infiltration
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Kayleigh Peters and others
Journal of Leukocyte Biology, Volume 116, Issue 5, November 2024, Pages 1054–1060, https://doi.org/10.1093/jleuko/qiae116
Published: 24 May 2024
...), the role of TIGIT on experimental autoimmune uveitis and Th17 cells, and the impact of Treg generation following TIGIT stimulation. TIGIT stimulation at the onset of clinical symptoms reduced the severity of uveitis and suppressed infiltration of Th17 cells into the eye. Further, Tregs from mice treated...
Journal Article
Paediatric non-infectious granulomatous uveitis: a retrospective cohort study
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Ai Tien Nguyen and others
in
Rheumatology
Rheumatology, Volume 64, Issue 3, March 2025, Pages 1333–1340, https://doi.org/10.1093/rheumatology/keae253
Published: 06 May 2024
... Uveitis Nomenclature (SUN) International Working Group, considering both the anatomical location (anterior, intermediate, posterior, or panuveitis) and the severity of inflammation at diagnosis (flare and anterior segment and/or vitreous cells graded from 0 to 4 +). The course of the uveitis was reported...
Journal Article
SELECTED PAPER
Significant association of HLA-A26 with uveitis and gastrointestinal involvement in patients with Behçet’s disease in a multicentre study
Tomoya Nakajima and others
Modern Rheumatology, Volume 34, Issue 6, November 2024, Pages 1221–1225, https://doi.org/10.1093/mr/roae022
Published: 14 March 2024
... Central Hospital between 2006 and 2016 (n = 200). Disease severity was evaluated using the Krause score. Results Uveitis and gastrointestinal involvement were observed in 95/196 and 57/167 patients, respectively. The HLA alleles identified were HLA-B51 (n = 52/106), HLA-A26...
Journal Article
Predictors of lack of response to methotrexate in juvenile idiopathic arthritis associated uveitis
Chiara Mapelli and others
in
Rheumatology
Rheumatology, Volume 64, Issue 2, February 2025, Pages 798–804, https://doi.org/10.1093/rheumatology/keae079
Published: 08 February 2024
... associated with a higher risk of developing uveitis in children with JIA [ 7 , 10 , 11 ]. Risk factors for poor visual prognosis in JIA-U patients include the activity grade of uveitis at onset, the presence of ocular damage at the first ophthalmologic evaluation, uveitis antedating arthritis and male...
Journal Article
Comparative risk of incident and recurrent acute anterior uveitis across different biological agents in patients with ankylosing spondylitis
Oh Chan Kwon and others
in
Rheumatology
Rheumatology, Volume 64, Issue 2, February 2025, Pages 588–596, https://doi.org/10.1093/rheumatology/keae003
Published: 18 January 2024
... of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Objective To evaluate the comparative risk of incident and recurrent acute anterior uveitis (AAU) across different biological DMARDs (bDMARDs) in patients...
Journal Article
Foxo1 drives the TGFβ1-dependent dichotomy of Th17 cell fates
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Mengjuan Zhang and others
Journal of Leukocyte Biology, Volume 117, Issue 1, January 2025, qiae004, https://doi.org/10.1093/jleuko/qiae004
Published: 09 January 2024
... of Th17 cell differentiation and its implications for autoimmunity. We employ a variety of experimental approaches, including utilizing an experimental autoimmune uveitis (EAU) mouse model, and uncover a correlation between disease severity and Foxo1 expression levels. Moreover, different pTh17...
Journal Article
Paediatric Cogan Syndrome masquerading as IgA vasculitis
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Praveen K Ramani and others
Modern Rheumatology Case Reports, Volume 8, Issue 1, January 2024, Pages 229–236, https://doi.org/10.1093/mrcr/rxad060
Published: 31 October 2023
... missed. On histopathology, the cornea reveals plasma cells, lymphocytes, and varying degrees of neovascularisation [ 14 ]. Inflammation may involve other ocular tissues in the atypical form of Cogan Syndrome. Uveitis, iritis, scleritis, optic neuritis, and chorioretinitis are less frequent but reported...
Journal Article
Non-infectious uveitis referred for pediatric rheumatologic assessment and management: A Portuguese retrospective study
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Hugo Gonçalves and others
Modern Rheumatology, Volume 34, Issue 4, July 2024, Pages 798–805, https://doi.org/10.1093/mr/road083
Published: 12 August 2023
...-square tests for the comparison of proportions of categorical variables. P values less than .050 were considered statistically significant. Complications epidemiology etiology pediatric uveitis treatment Uveitis is a nosological entity, which involves inflammation in virtually any...
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