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Keywords: superoxide dismutase
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Journal Article
Characterization of two cellular superoxide dismutases in Protohermes xanthodes (Megaloptera: Corydalidae) in response to sublethal chlorpyrifos stress
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Jie Yang and others
Environmental Entomology, Volume 54, Issue 2, April 2025, Pages 309–319, https://doi.org/10.1093/ee/nvaf015
Published: 13 February 2025
... into the environment are increasingly recognized as a global threat to freshwater ecosystems because of their adverse effects on non-target organisms, particularly aquatic insects and other arthropods. Superoxide dismutases (SODs) are important antioxidant enzymes that play a crucial role in protecting organisms from...
Journal Article
Deciduous and evergreen perennials have higher antioxidant levels and more reactive oxygen species-susceptible chlorophyll-binding proteins
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Kenyon J Nisbett and others
Biological Journal of the Linnean Society, Volume 144, Issue 1, January 2025, blae102, https://doi.org/10.1093/biolinnean/blae102
Published: 02 January 2025
... damage. Although carotenoid levels did not differ between annuals and perennials, we found that deciduous perennials had higher activity of the ascorbate–glutathione cycle, and evergreen perennials had higher activity of superoxide dismutase (SOD, EC 1.15.1.1). The second hypothesis was that chlorophyll...
Journal Article
Impact of a trace mineral injection at weaning on growth, behavior, and inflammatory, antioxidant, and immune responses of beef calves
Marcelo Vedovatto and others
Translational Animal Science, Volume 8, 2024, txae177, https://doi.org/10.1093/tas/txae177
Published: 26 December 2024
... ≤ 0.05) between treatments. The means reported were adjusted for a covariate (baseline data from day 0). Figure 2. Plasma superoxide dismutase (SOD; A) and glutathione peroxidase (GSH-px; B) of Nellore calves receiving saline solution (saline; n = 14) or ITM (n = 14) at weaning (day 0...
Journal Article
SoxR-dependent regulation of sodA1 and its impact on Stenotrophomonas maltophilia survival under external oxidative stress
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Suparat Giengkam and others
FEMS Microbiology Letters, Volume 372, 2025, fnae112, https://doi.org/10.1093/femsle/fnae112
Published: 24 December 2024
... superoxide dismutase Chulabhorn Research Institute 10.13039/501100007959 49892/4759806 Abstract Stenotrophomonas maltophilia is an emerging global opportunistic pathogen that causes nosocomial infections. We demonstrated that the superoxide stress-sensing transcriptional regulator SoxR directly...
Journal Article
Testosterone variation in a semi-captive population of Asian elephants in Myanmar
Héloïse Moullec and others
Conservation Physiology, Volume 12, Issue 1, 2024, coae076, https://doi.org/10.1093/conphys/coae076
Published: 22 November 2024
... glucocorticoid metabolite (FGM) and heterophil to lymphocyte ratio (H/L)] and oxidative status (reactive oxygen metabolite concentrations and superoxide dismutase activity). We reported that FTM increased with age from juvenile to adulthood for both sexes, with higher FTM concentrations in males than females...
Journal Article
Antioxidant activity and whitening effect of vitamin C and superoxide dismutase from Rosa roxburghii Tratt
Hong Wu and others
Food Quality and Safety, Volume 9, 2025, fyae046, https://doi.org/10.1093/fqsafe/fyae046
Published: 08 November 2024
... as a potential source of skin-lightening compounds. Vitamin C (Vc) and superoxide dismutase (SOD)-rich extracts were extracted from RR, namely RRVC and RRSOD, using macroporous resin column chromatography and graded ammonium sulfate precipitation. The antioxidant and skin-lightening effects of these extracts...
Journal Article
PSIII-24 Skeletal muscle antioxidant activity increases over time in beef steers and is greater in Angus compared with Brahman
Brooke D Williams and others
Journal of Animal Science, Volume 102, Issue Supplement_3, September 2024, Pages 508–509, https://doi.org/10.1093/jas/skae234.575
Published: 14 September 2024
... between Angus and Brahman steers which may mitigate oxidative stress, impacting growth performance as well as product quality at harvest. glutathione peroxidase superoxide dismutase Abstract citation ID: skae234.575 PSIII-24 Skeletal muscle antioxidant activity in- creases over time in beef steers...
Journal Article
EDITOR'S CHOICE
Maternal folic acid over-supplementation impairs cardiac function in mice offspring by inhibiting SOD1 expression
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Ke Cai and others
Cardiovascular Research, Volume 120, Issue 16, November 2024, Pages 2092–2103, https://doi.org/10.1093/cvr/cvae203
Published: 10 September 2024
... at the transcriptional level possibly due to increased DNA methylation. Among these, superoxide dismutase 1 was down-regulated, and reactive oxygen species (ROS) levels increased in the mouse heart. Inhibition of ROS generation using the antioxidant N-acetylcysteine rescued the impaired cardiac function resulting from...
Journal Article
Increase of HCN current in SOD1-associated amyotrophic lateral sclerosis
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Hsing-Jung Lai and others
in
Brain
Brain, Volume 147, Issue 12, December 2024, Pages 4240–4253, https://doi.org/10.1093/brain/awae248
Published: 01 August 2024
... of patients with sporadic ALS and an ALS mouse model with superoxide dismutase 1 (SOD1)/G93A transgenes using nerve excitability tests (NETs) to investigate axonal membrane properties and chemical precipitation, followed by ELISA analysis to measure plasma misfolded protein levels. Six...
Journal Article
Betaine activates the Nrf2-Keap1-ARE pathway by increasing the methylation level of Keap1 DNA promoter
Mengmeng Zhang and others
International Journal of Food Science and Technology, Volume 59, Issue 9, September 2024, Pages 6231–6242, https://doi.org/10.1111/ijfs.17359
Published: 18 July 2024
...Mengmeng Zhang; Tianchui Wang; Sixian Ou; Yucong Zou; Xuan Xin DNA methyltransferase DNA promoter glutathione peroxidase heme oxygenase-1 methionine cycle methyl donor methylation Nrf2 pathway superoxide dismutase Basic and Applied Basic Research Foundation of Guangdong Province 10.13039...
Journal Article
Effects of high doses of zearalenone on some antioxidant enzymes and locomotion of Tenebrio molitor larvae (Coleoptera: Tenebrionidae)
Milena Janković-Tomanić and others
Journal of Insect Science, Volume 24, Issue 3, May 2024, 6, https://doi.org/10.1093/jisesa/ieae052
Published: 08 May 2024
... of the most important effects of ZEA is the induction of oxidative stress, which leads to physiological and behavioral changes. This study deals with the effects of high doses of ZEA (10 and 20 mg/kg) on survival, molting, growth, weight gain, activity of antioxidant enzymes superoxide dismutase (SOD...
Journal Article
Vcp overexpression and leucine supplementation extend lifespan and ameliorate neuromuscular junction phenotypes of a SOD1G93A-ALS mouse model
Tzyy-Nan Huang and others
Human Molecular Genetics, Volume 33, Issue 11, 1 June 2024, Pages 935–944, https://doi.org/10.1093/hmg/ddae022
Published: 21 February 2024
... function. The first causative gene of ALS to be identified was SuperOxide Dismutase 1 (SOD1) [ 18 ], which accounts for 10%–20% of familial cases [ 19 , 20 ]. The SOD1 protein is involved in converting superoxide radicals to oxygen and hydrogen peroxide [ 21 , 22 ], indicating a role...
Journal Article
Mutations of ribosomal protein genes induce overexpression of catalase in Saccharomyces cerevisiae
Ching-Hsiang Hsu and others
FEMS Yeast Research, Volume 24, 2024, foae005, https://doi.org/10.1093/femsyr/foae005
Published: 25 January 2024
... exhibit reduced activities of several antioxidant enzymes, including superoxide dismutase (SOD), glucose-6-phosphate dehydrogenase, and glutathione reductase (Schnell et al. 1992 ). Msn2 and Msn4, which share a 66% sequence homology and contain zinc finger binding motifs at the C-terminus (Estruch...
Journal Article
Role of oxidative stress in neurodegenerative disorders: a review of reactive oxygen species and prevention by antioxidants
Annwyne Houldsworth
Brain Communications, Volume 6, Issue 1, 2024, fcad356, https://doi.org/10.1093/braincomms/fcad356
Published: 02 January 2024
... oxygen species. Antioxidants can powerfully neutralize reactive oxygen species and free radicals, decreasing oxidative damage. Antioxidant genes, like the manganese superoxide dismutase enzyme, can undergo epigenetic changes that reduce their expression, thus increasing oxidative stress in tissue...
Journal Article
Novel biomarkers and pathophysiology of membranous nephropathy: PLA2R and beyond
Corrado Murtas and others
Clinical Kidney Journal, Volume 17, Issue 1, January 2024, sfad228, https://doi.org/10.1093/ckj/sfad228
Published: 11 December 2023
... is still irreplaceable. glomerulonephritis membranous nephropathy oxidative systems phospholipase-A2 superoxide dismutase Membranous nephropathy (MN) is the most common cause of nephrotic syndrome among Caucasian adults while it rarely occurs in the pediatric setting. It is an autoimmune condition...
Journal Article
Specific antioxidant enzymes are involved in the freeze-thawing response of industrial baker’s yeasts
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María F Kronberg and others
Letters in Applied Microbiology, Volume 76, Issue 10, October 2023, ovad117, https://doi.org/10.1093/lambio/ovad117
Published: 27 September 2023
.... That, in turn, could be positively associated with Y8’s higher constitutive activities of cytosolic catalase (CAT) and superoxide dismutase by a significant activation (25%) of Y8 CAT after F-T. That would complement the protective effects of other protectant molecules like trehalose, present at high...
Journal Article
Methyl viologen-induced changes in the Arabidopsis proteome implicate PATELLIN 4 in oxidative stress responses
Pavol Melicher and others
Journal of Experimental Botany, Volume 75, Issue 1, 1 January 2024, Pages 405–421, https://doi.org/10.1093/jxb/erad363
Published: 20 September 2023
... Arabidopsis and oxidative stress-hypersensitive fsd1-1 and fsd1-2 knockout mutants, which are deficient in IRON SUPEROXIDE DISMUTASE 1 (FSD1). The levels of proteins that are localized in chloroplasts and the cytoplasm were modified in all lines treated with methyl viologen. Compared...
Journal Article
In vitro maturation of NiSOD reveals a role for cytoplasmic histidine in processing and metalation
Priyanka Basak and others
in
Metallomics
Metallomics, Volume 15, Issue 11, November 2023, mfad054, https://doi.org/10.1093/mtomcs/mfad054
Published: 18 September 2023
... import of Ni(II) via the bacterial NikA(BCDE) transporter system. 8 , 9 Evidence for the participation of the labile metal pool in metalloenzyme maturation was heretofore unexamined. Nickel superoxide dismutase (NiSOD) is the nickel-specific member of the SOD class of enzymes that catalyze...
Journal Article
Exogenous monoterpenes mitigate H2O2-induced lipid damage but do not attenuate photosynthetic decline during water deficit in tomato
Hao Zhou and others
Journal of Experimental Botany, Volume 74, Issue 17, 13 September 2023, Pages 5327–5340, https://doi.org/10.1093/jxb/erad219
Published: 05 June 2023
...-regulate the activity of key antioxidant enzymes (superoxide dismutase and ascorbate peroxidase) even though higher (2.5 and 5 mM) spray concentrations did, suggesting a complex role for monoterpenes in mediating antioxidant processes. Furthermore, soil drying caused similar photosynthetic limitations...
Journal Article
Association between Serum α-Klotho Levels and Behçet Disease
Mohammad Reza Jafari Nakhjavani and others
Laboratory Medicine, Volume 54, Issue 5, September 2023, Pages 469–472, https://doi.org/10.1093/labmed/lmac146
Published: 13 January 2023
... Sciences 10.13039/501100004366 Behçet disease α-klotho klotho proteins endothelial dysfunction vasculitis superoxide dismutase 2 Abstract Background Endothelial dysfunction (ED) has a well-known role in promoting vascular inflammation in Behçet disease (BD). α-klotho is involved in regulation...
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