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Cigarette Smoking is Associated with Levels of the Serotonin Transporter in the Brain: A [11C]DASB PET Study
Paul Faulkner and others
International Journal of Neuropsychopharmacology, pyaf026, https://doi.org/10.1093/ijnp/pyaf026
Published: 21 April 2025
... provides the first in vivo evidence that current smoking may be associated with elevated hippocampal SERT binding – possibly reflecting lower synaptic serotonin concentrations, and that this change may normalize following smoking cessation. Smoking nicotine serotonin 5-HT positron emission...
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Onset ages of cerebrovascular disease and amyloid and effects on cognition in risk-enriched cohorts
Lianlian Du and others
Brain Communications, fcaf158, https://doi.org/10.1093/braincomms/fcaf158
Published: 19 April 2025
... Graphical Abstract Alzheimer’s disease white matter hyperintensities positron emission tomography time operationalization preclinical cognitive decline Manuscripts submitted to Brain Communications Page 2 of 38 ACCEPTED MANUSCRIPT 1 2 3 4 Onset ages of cerebrovascular disease and amyloid and effects 5 6...
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Factors affecting the performance of a novel artificial intelligence-based coronary computed tomography-derived ischaemia algorithm
Peerapon Kiatkittikul and others
European Heart Journal - Imaging Methods and Practice, Volume 2, Issue 4, October 2024, qyaf033, https://doi.org/10.1093/ehjimp/qyaf033
Published: 17 April 2025
.... Objective To identify factors associated with discrepancy between AI-QCTischaemia and positron emission tomography (PET) perfusion. Methods and results Six hundred and sixty-two patients with suspected obstructive coronary artery disease (CAD) on CCTA and undergoing [15O...
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Microglia positron emission tomography and progression in multiple sclerosis: thalamus on fire
Burcu Zeydan and others
Brain Communications, fcaf141, https://doi.org/10.1093/braincomms/fcaf141
Published: 16 April 2025
... multiple sclerosis thalamus microglia positron emission tomography magnetic resonance imaging Page 1 of 39 Manuscripts submitted to Brain Communications 1 2 3 4 Microglia positron emission tomography and progression 5 6 7 in multiple sclerosis: thalamus on fire 8 9 10 Burcu Zeydan M.D. 1,2, Nur Neyal...
Journal Article
Hepatic Glucose Uptake During Euglycemic Hyperinsulinemia Associates With Glycemia During Oral Glucose Tolerance Test
Miikka-Juhani Honka and others
Journal of the Endocrine Society, Volume 9, Issue 5, May 2025, bvaf054, https://doi.org/10.1210/jendso/bvaf054
Published: 02 April 2025
... not have diabetes from the CMgene study cohort. Hepatic GU was measured with [18F]fluorodeoxyglucose ([18F]FDG) and positron emission tomography. Results In a multiple regression analysis, hepatic GU, endogenous glucose production, insulin secretion capacity, and serum...
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A 3-Week Ketogenic Diet Increases Global Cerebral Blood Flow and Brain-Derived Neurotrophic Factor
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Thien Vinh Luong and others
The Journal of Clinical Endocrinology & Metabolism, dgaf207, https://doi.org/10.1210/clinem/dgaf207
Published: 02 April 2025
... (SDD). Each diet period concluded with a positron emission tomography (PET) study day, accompanied by a separate magnetic resonance imaging (MRI) scan. Blood samples were collected prior to the PET scan to measure β-hydroxybutyrate (β-OHB) and BDNF levels. CBF was assessed using a [15O...
Journal Article
Deep learning-quantified body composition from positron emission tomography/computed tomography and cardiovascular outcomes: a multicentre study
Robert J H Miller and others
European Heart Journal, ehaf131, https://doi.org/10.1093/eurheartj/ehaf131
Published: 30 March 2025
... the original work is properly cited. Abstract Background and Aims Positron emission tomography (PET)/computed tomography (CT) myocardial perfusion imaging (MPI) is a vital diagnostic tool, especially in patients with cardiometabolic syndrome. Low-dose CT scans are routinely performed with PET...
Journal Article
Why, how and when to look for occult giant cell arteritis in patients with polymyalgia rheumatica
Daniel Blockmans
in
Rheumatology
Rheumatology, Volume 64, Issue Supplement_1, March 2025, Pages i55–i58, https://doi.org/10.1093/rheumatology/keae513
Published: 12 March 2025
... arteritis vasculitis positron emission tomography ultrasound temporal artery biopsy Rheumatology key messages Subclinical vasculitis is found in 9–23% of patients with pure PMR, depending on the imaging method used and the criteria used for defining vasculitis. Patients with pure PMR...
Journal Article
Biopsy vs imaging in the diagnosis of giant cell arteritis. Viewpoint 1: in favour of imaging
Wolfgang Andreas Schmidt
in
Rheumatology
Rheumatology, Volume 64, Issue Supplement_1, March 2025, Pages i71–i73, https://doi.org/10.1093/rheumatology/keae487
Published: 12 March 2025
...Wolfgang Andreas Schmidt giant cell arteritis large-vessel vasculitis polymyalgia rheumatica ultrasound magnetic resonance imaging computed tomography positron emission tomography angiography temporal artery biopsy histology Updated EULAR Recommendations on Imaging in Large-vessel...
Journal Article
Imaging small dynamic lesions using positron emission tomography and computed tomography: an 18F-sodium fluoride valvular phantom study
Anna K Barton and others
European Heart Journal - Imaging Methods and Practice, Volume 3, Issue 1, January 2025, qyaf013, https://doi.org/10.1093/ehjimp/qyaf013
Published: 28 February 2025
... Abstract positron emission tomography cardiac phantom cardiac computed tomography multi-modality imaging National Heart, Lung, and Blood Institute 10.13039/100000050 National Institutes of Health 10.13039/100000002 Conflict of interest: A.K.B and H.H. were supported by a grant from the Dr...
Journal Article
Using 18F-FDG PET/CT to predict programmed cell death ligand expression in non-small cell lung cancer via metabolic tumour heterogeneity
Ruxi Chang and others
British Journal of Radiology, Volume 98, Issue 1169, May 2025, Pages 715–720, https://doi.org/10.1093/bjr/tqaf034
Published: 20 February 2025
... conventional imaging in providing immunohistochemical information before biopsy. Advances in knowledge COV of the primary tumour can predict PD-L1 expression, potentially complementing conventional imaging for immunohistochemical information prior to biopsy. positron emission tomography/computed tomography...
Journal Article
IN VIVO CLASSIFICATION OF TAU PATHOLOGIES BY POSITRON EMISSION TOMOGRAPHY IN PATIENTS WITH FRONTOTEMPORAL DEMENTIA
*Manabu Kubota and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Page i208, https://doi.org/10.1093/ijnp/pyae059.363
Published: 12 February 2025
.... Aims & Objectives In this study, we aimed to classify patients with FTD based on topologies of tau protein aggregates captured by positron emission tomography (PET) with 18F-florzolotau (aka 18F-APN-1607, 18F-PM-PBB3), which allows high-contrast imaging of diverse tau fibrils in Alzheimer’ s...
Journal Article
ALTERED PATTERNS OF ASSOCIATION BETWEEN TSPO BINDING AND MGLUR5 AVAILABILITY IN VIVO IN DRUG-NAIVE PATIENTS WITH MAJOR DEPRESSIVE DISORDER: A PRELIMINARY DUAL-TRACER PET STUDY
*Jong-Hoon Kim and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i137–i138, https://doi.org/10.1093/ijnp/pyae059.238
Published: 12 February 2025
... therapeutic approaches (2-4); however, the patterns of interregional correlations between neuroinflammation and glutamatergic signaling in MDD has not been directly investigated using in vivo positron emission tomography (PET) imaging. Aims & Objectives In this preliminary dual-tracer PET study, we...
Journal Article
HIGH-TEMPORAL RESOLUTION PET/MRIREVEALS DISTINCT METABOLIC AND HEMODYNAMIC WORKING MEMORY RESPONSES IN HUMAN POSTERIOR CINGULATE CORTEX
*Sebastian Klug and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Page i274, https://doi.org/10.1093/ijnp/pyae059.484
Published: 12 February 2025
... assessment of these influences in the temporal domain was limited due to the inherently low temporal resolution of positron emission tomography (PET) when compared to functional magnetic resonance imaging (fMRI). Aims & Objectives We employed high temporal resolution functional PET (fPET...
Journal Article
NON-INVASIVE FUNCTIONAL PET – A NOVEL APPROACH TO ASSESS TASK-SPECIFIC CEREBRAL GLUCOSE METABOLISM
*Godber Mathis Godbersen and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Page i24, https://doi.org/10.1093/ijnp/pyae059.042
Published: 12 February 2025
...*Godber Mathis Godbersen; Pia Falb; Sebastian Klug; Leo Richard Silberbauer; Murray Bruce Reed; Lukas Nics; Marcus Hacker; Rupert Lanzenberger; Andreas Hahn functional positron emission tomography (fPET) [18F]-fluorodeoxyglucose ([18F]FDG) arterial input function non-invasive PET imaging...
Journal Article
NO DIFFERENCES IN SYNAPTIC DENSITY IN TWINS WITH AUTISM AND THEIR NON-AUTISTIC CO-TWINS. HOWEVER, ARE DIFFERENCES IN SV2A BINDING POTENTIAL IN AUTISTIC BRAINS A MATTER OF WHITE MATTER?
*Gina Griffioen-Järfalk and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i35–i36, https://doi.org/10.1093/ijnp/pyae059.062
Published: 12 February 2025
...*Gina Griffioen-Järfalk; Martin Bolin; Vladimir Stephanov; Simon Cervenka; Miguel Castelo-Branco; Ricardo Martins; Johan Lundberg; Chirag Mehra; Oliver Howes; Declan Murphy; Sven Bölte; Lars Farde; Jacqueline Borg autism synaptopathology positron emission tomography connectivity twin study...
Journal Article
MULTIMODAL ASSESSMENT OF DOPAMINE SYNTHESIS AND BOLD- SIGNALING IN REWARD AND PUNISHMENT PROCESSING - A HYBRID FPET/FMRI STUDY
*Clemens Schmidt and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i39–i40, https://doi.org/10.1093/ijnp/pyae059.068
Published: 12 February 2025
... and Caudate Nucleus During Stimulus-Action-Reward Association Learning’, Journal of Neurophysiology, 95(2), pp. 948–959. https://doi.org/10.1152/jn.00382.2005 . PET/MRI 6-[18F]-fluoro-l-dopa (6-[18F]FDOPA) functional imaging functional positron emission tomography (fPET) reward Abstracts CINP2024...
Journal Article
FUNCTIONAL DYNAMICS OF SEROTONIN SYNTHESIS DURING MONETARY REWARD AND PUNISHMENT PROCESSING – A HYBRID FPET/FMRI STUDY
*Clemens Schmidt and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i64–i65, https://doi.org/10.1093/ijnp/pyae059.110
Published: 12 February 2025
... positron emission tomography (fPET) allows to assess neurobiological underpinnings of cognitive performance on a neurotransmitter level (2). Besides dopamine, the serotonergic system plays an essential modulating role in reward processing as evidenced by preclinical and human studies (3). Aims...
Journal Article
18F-FDG PET or PET/CT in detecting high-grade transformation of chronic lymphocytic leukaemia and indolent lymphomas: a systematic review and meta-analysis
Osher N Y Lee and others
British Journal of Radiology, Volume 98, Issue 1169, May 2025, Pages 669–678, https://doi.org/10.1093/bjr/tqaf028
Published: 11 February 2025
...://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Objectives To evaluate the diagnostic accuracy of 18F-FDG positron emission tomography (PET) or PET/computed tomography (CT...
Journal Article
Investigation of patterns and associations of neuroinflammation in cognitive impairment
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Ruoqiu Gan and others
Cerebral Cortex, Volume 35, Issue 2, February 2025, bhaf013, https://doi.org/10.1093/cercor/bhaf013
Published: 07 February 2025
... and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Positron emission tomography (PET) has many available and evolving imaging agents. It plays an irreplaceable role in the imaging...
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