... the original work is properly cited. See the journal About page for additional terms. Abstract Context Pituitary adenomas and cysts are rare in pediatric patients and improved understanding can guide management recommendations. Objective To report incidence, presentation, management, and outcomes...

... management of a subset of PitNETs and that these results may need to be interpreted with consideration of patient age and sex. DOTATATE immunohistochemistry PitNET pituitary adenoma SSTR2 Pituitary neuroendocrine tumors (PitNETs), also known as pituitary adenomas, are among the most common intracranial...

... other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. See the journal About page for additional terms. Abstract Prolactin-secreting pituitary adenomas are typically...

... unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. See the journal About page for additional terms. Abstract A 62-year-old Sudanese female was diagnosed with a nonfunctioning pituitary adenoma in 2006. Despite undergoing 3 transsphenoidal surgeries...

... pmol/L), and total triiodothyronine (T3) 91 ng/dL (140 nmol/L) (normal reference range: 58-159 ng/dL; 89-244 nmol/L). Initial differential diagnoses included TSH-producing pituitary adenoma (TSH-oma) and amiodarone-induced thyrotoxicosis. His free T4 declined significantly postoperatively, favoring...

... in various organs and the central nervous system (CNS), including renal cell carcinoma or cysts, pheochromocytoma, pancreatic neuroendocrine tumors or cysts, benign cystadenomas of adnexal organs, and CNS hemangioblastomas [ 6 ]. To date, only a few cases of pituitary adenomas have been reported...

...: NCT03636568 endoscopic endonasal transsphenoidal surgery fluid restriction hyponatremia pituitary adenoma pituitary neuroendocrine tumor School of Medicine 10.13039/100008235 Key Points This randomized controlled trial tests the efficacy of postoperative fluid restriction (FR) to prevent delayed...

...-functioning pituitary adenoma; PH, plurihormonal; PIT1, pituitary transcription factor 1; PRL, prolactin; PRR, prevalence rate ratio; SF1, steroidogenic factor 1; TPIT, T-box family member TBX19; TSH, thyrotropin; TSR, transsphenoidal resection. ^aValues were estimated based on the percentage...

... programs, early intervention of neuropsychiatric comorbidities, and proactive rehabilitation plans as part of standard care. Medical Research Council of Southeast Sweden 10.13039/100010805 FORSS-981466 Cushing's disease socioeconomic educational level disability pension pituitary adenoma Abstract...

... the limitations of the SST. These data indicate to consider SST as a single test procedure for low-risk patients. pituitary adenoma adrenal insufficiency metyrapone hypopituitarism Significance Our large, single-centre analysis provides further support for the overnight metyrapone test (OMT) as a more...

... not previously characterized. familial isolated pituitary adenoma multiple endocrine neoplasia neuroendocrine neoplasm next-generation sequencing paraganglioma/pheochromocytoma pituitary neuroendocrine tumor Neuroendocrine neoplasms (NENs) comprise a heterogeneous group of lesions derived from cells...

... neoplasia type 1 (MEN-1) is a syndrome characterized by development of tumors including parathyroid adenomas, duodenopancreatic neuroendocrine tumors, and pituitary adenomas. We describe 1 patient with a novel and another with a rare pathogenic MEN-1 variant. Case 1 was a 61-year-old woman with recurrent...

.... Global patterns of DNA methylation may provide valuable insight into origins of pituitary adenoma subtypes, assist with PitNet diagnostics and have been found to correspond to the current WHO classification of PitNETs based on transcription factor lineage. Analysis of differentially methylated regions...

... patients with PG who have residual disease after surgical intervention. pituitary gigantism pituitary adenoma growth hormone excess Pituitary gigantism (PG) is a rare endocrine disorder that may present with multiple pituitary hormone abnormalities in pediatric patients. A hallmark presentation...

... (right ovary, 109 mL; left ovary, 146 mL). A 7-mm pituitary microadenoma was also observed, and 6 months after referral, endoscopic transsphenoidal surgery was performed, resulting in a diagnosis of FSH-producing pituitary adenoma. Nine months postoperatively, the ovarian cysts had markedly shrunk...

... in conjunction with other proteins. pro-opiomelanocortin proSAAS unfolded protein response Cushing disease nonfunctioning pituitary adenoma South-Eastern Norway Regional Health Authority 10.13039/501100006095 2020081/2020 Research Council of Norway INFRASTRUKTUR-program 295910 Corticotroph...

... in the cytoplasmic delivery of receptor-targeting ligands. somatostatin receptor 2 somatostatin receptor ligands neuroendocrine tumors acromegaly Cushing's disease pituitary adenoma All SSTRs are conventional G protein-coupled receptors (GPCRs) that possess a 7 transmembrane α-helix structure...

... the clinical and biochemical features of an RTHβ patient with a His435Arg pathogenic variant, who was initially misclassified as having a TSH-producing pituitary adenoma. In addition, we characterize the molecular and functional properties of this His435Arg pathogenic variant using different in vitro tests...

... Library between January 1, 2000 and January 31, 2021 for studies reporting on outcomes for pituitary adenoma, craniopharyngioma, and Rathke's cleft cyst (RCC) after TSS and providing definition of post-operative AVP-D. We pooled the results as proportions with 95% confidence intervals (CIs) using Freeman...

... adenomas are the third most common intracranial tumors comprising about 10%–15% of all tumors. Giant pituitary adenomas (GPAs) are a subset of pituitary tumors. Most giant adenomas are slowly growing and histologically benign in nature despite the giant in size and difficulties to manage. Diverse surgical...