... environment. This has raised concerns about the potential health impacts of EMFs. Previous studies have indicated that EMFs may influence male infertility, with oxidative stress proposed as a key factor; however, the underlying mechanisms remain unclear. In this study, we aimed to determine whether EMFs...

... disorganization and swelling in myocardial tissue. At the molecular level, SiNPs exposure upregulated hypertrophic markers (β-MHC, ANP), inflammatory cytokines (IL-18, IL-1β), and oxidative stress markers MDA, while reducing SOD levels. Both classical (Caspase-1) and non-classical (Caspase-4, Caspase-5...

...-17D binds with CD93 and involved in multiple pathways. (B) Detailed presentation of multifaceted role of IL-17D in response to oxidative stress. Nrf2 induces IL-17D expression under hyperoxia and promotes the expression of multiple chemokines. Hyperoxia-generated ROS activate MAPK/ERK. IL-17...

...Tongyao Zhang; Yajie Liao; Jitao Ling; Jing Zhang; Deju Zhang; Xiaoping Yin; Peng Yu; Xiao Liu Microplastics Nanoplastics Cardiovascular diseases Endothelial cell toxicity Oxidative stress Atherosclerosis Inflammatory pathways Coagulation dynamics Thrombus formation Immune cell function...

... composition differed between genera and was significantly affected by temperature and oxidative stress. The metabolic profile of coral holobionts was primarily shaped by symbionts identity, but was also strongly responsive to oxidative stress. At peak temperature stress, betaine lipids in Cladocopium...

... model oxidative stress physiological model Scleractinia Climate change is increasing the frequency and intensity of marine heatwaves (MHWs), which impact coral reefs globally. Anomalously high seawater temperatures associated with thermal stress events have resulted in a global decline in coral...

...) dialyzer on MM removal and biocompatibility parameters including inflammation and oxidative stress remain to be investigated. Methods This non-inferiority cross-over prospective randomized study included 36 patients randomly assigned to receive either 3 months of MCO-HD followed by 3 months of SHFVE-HD...

...Tong Meng; Rui Feng; Yunlong Zhu; Jincheng Luo; Andong Zhang; Yi Liu; Jing Chen; Cheng Yang CP/CPPS Sulforaphane NLRP3 inflammasome Nrf2 Oxidative stress Accepted Manuscript Sulforaphane relieved inflammation symptoms in EAP mice by blocking oxidative stress and NLRP3 inflammasome activation...

... on histone acetyltransferase GCN5 regulation through functional thiols . Journal of Experimental Botany   76 , 1569 – 1584 . Gaupe   AC , Begley   TJ , Tenniswood   M.   2015 . Gcn5 modulates the cellular response to oxidative stress and histone deacetylase inhibition . Journal...

... alcohol containing beverages as carcinogenic ( Baan et al. 2007 ). Although some progress has been made in the last years to identify mechanisms of alcohol mediated carcinogenesis, many questions still remain unsolved. Some of these mechanisms are involved in both AALD and AMC including oxidative stress...

... ferroptosis GSTP1 atrial fibrillation oxidative stress ACCEPTED MANUSCRIPT 1 GSTP1 inhibits angiotensin II-induced atrial fibrillation by regulating 2 ferroptosis 3 Han Li1,2 Zhenyu Feng1 Benke Li3 , Jie Bai4, Qiu-yue Lin1, Xiaohong Yu1, 4 Ningning Zhang1 Yunpeng Xie1 Xiaolei Yang1,# 5 1 The first...

... This study was designed to adjust effective chemotherapy doses of cabazitaxel (CBZ) on cognitive behaviors, inflammatory cytokines and oxidative stress parameters, and survival rate in C6-induced GBM of rats. Male Sprague–Dawley rats bearing intra-caudate nucleus (CN) C6 inoculation were randomly divided...

... study aimed to uncover the consequences of heat stress during oocyte maturation on mitochondrial health, cellular oxidative stress response, and its implications for endoplasmic reticulum stress. Immature bovine oocytes were matured either under routine temperatures (38.8°C, Control) or exposed...

... disorders in the endoplasmic reticulum (ER) lumen by activating the unfolded protein response. Many studies have demonstrated a potential link between ERS and PE pathogenesis by mediating genetic susceptibility, placental hypoxia, oxidative stress, metabolic disorders, impaired angiogenesis and function...

... μmol/L or less. Mechanistically, the application of 1–2 μmol/L bisphenol A directly increased the intracellular oxidative stress levels, significantly increased the cytoplasmic calcium and nitric oxide contents, decreased the mitochondrial membrane potential, activated caspases-9 and -3, and triggered...

... Abstract chronic kidney disease adenine aromatic amino acids oxidative stress SLC7A5 transporter National Natural Science Foundation of China 10.13039/501100001809 82204595 U23A20517 Fundamental Research Program of Shanxi Province 202303021221070 China Postdoctoral Science Foundation...

... the human body through ingestion, inhalation, and dermal absorption and, once internalized, can induce oxidative stress, inflammation, endocrine disruption, and cellular damage leading to impaired male reproductive health. The present narrative review explores the biological pathways through which...

... oxidative stress and mitochondrial-mediated apoptosis, underscoring its potential as a therapeutic agent for hypoxia-induced myocardial damage. Graphical Abstract Graphical Abstract Potentilla anserina flavonoids hypoxia myocardial cells oxidative stress mitochondrial apoptosis Xizang...

... or 24 h of reperfusion. C57BL/6J mice underwent 30′ of ischaemia, followed by 10′, 2, 12, 24 h, or 4 weeks of reperfusion. Hearts and isolated cardiomyocytes (CMs) were analysed for gene expression. We assessed cardiac function, infarct size (IS), oxidative stress, and fibrosis in mice subjected...

... ageing mating costs telomeres oxidative stress mosquitofish ASSAB 10.13039/501100022868 Australian Research Council 10.13039/501100000923 DP190100279 Life history theory is based on organisms having limited available resources that create trade-offs in investment among growth...