..., the mechanisms that tightly control our cardiovascular system may become less efficient, particularly the reflexes that control BP [ 8 ]. This may be lead to BP Instability, often characterised by orthostatic hypotension (OH), which is usually due to a combination of baroreceptor failure and cardiovascular...

... revealed two localized myocardial scars: one at the basal anterior wall from the 2018 ischaemic event and another in the mid infero-septal wall at the site of the LBBAP lead. During her hospital stay, she experienced multiple episodes of near fainting due to orthostatic hypotension, indicative...

... Background Orthostatic hypotension (OH) is an important differential diagnosis in unexplained syncope. Neurogenic OH (nOH) has been postulated to differ from non-neurogenic OH (non-nOH), yet pathophysiological differences are largely unexplored. We aimed to investigate etiology and tilt table test (TTT...

... for the diagnosis and management of syncope . Eur Heart J   2018 ; 39 : 1883 – 1948 . 2 Ricci   F , De Caterina   R , Fedorowski   A . Orthostatic hypotension: epidemiology, prognosis, and treatment . J Am Coll Cardiol   2015 ; 66 : 848 – 860 . 3 Freeman   R , Abuzinadah   AR...

... < .05. Statistical analyses were performed using GraphPad Prism (v.9.4.1, GraphPad, USA). Figures were created using GraphPad Prism, and Adobe Illustrator (Adobe Systems Inc., USA). S.R.R.: consultant for Theravance Biopharma and Amneal Pharma related to neurogenic orthostatic hypotension...

... paroxysmal positional vertigo (BPPV) orthostatic hypotension falls prospective systematic review older people This systematic review and meta-analysis examined the association between dizziness and future falls and/or injurious falls in older adults. Older adults with dizziness had a significantly...

... hypotension is associated with cardiovascular disease. It remains unclear if low standing blood pressure or high seated blood pressure is responsible for this association. We compared associations of orthostatic hypotension and hypertension with high-sensitivity cardiac troponin I and N-terminal pro-B-type...

... medium, provided the original work is properly cited. Abstract Aims The pathophysiology of orthostatic hypotension (OH), a common clinical condition, associated with adverse outcomes, is incompletely understood. We examined the relationship between OH and circulating endostatin, an endogenous...

... out. Reflex syncope and orthostatic hypotension are the most frequent aetiologies of non-cardiac syncope. As no specific therapy is effective for all types of non-cardiac syncope, identifying the underlying haemodynamic mechanism is the essential prerequisite for an effective personalized therapy...

...: 247 899, 55.3%; mean age: 56.8 ± 8.1 years) were included in the present analysis, of which 3 795 (0.8%) had orthostatic hypotension. Table 1 shows the baseline characteristics of the participants grouped by orthostatic hypotension status. Overall, participants with orthostatic hypotension were...

..., resulting in injuries, accidents or even death. In our ageing society, the subsequent healthcare usage, such as emergency room presentations, surgeries and hospital admissions, forms a significant and growing socioeconomic burden. Causes of syncope in the older adult include orthostatic hypotension, carotid...

...Qiao Xiong; Fang Li; Haiyan Chi; Yachao Yang; Mengfan Li; Yingxiao Liu; Yupan Zhang; Bing Leng; Xiaoxiao Qi; Hairong Sun; Zhenguang Li; Jinbiao Zhang Abstract Context In type 2 diabetes mellitus (T2DM), orthostatic hypotension (OH) is associated with cognition, but the mechanisms governing...

... performed. Results One hundred and eighty-four studies were included: 181 observational and 3 interventional. Several cardiovascular disorders, including stroke, coronary artery disease, valvular heart disease, arterial stiffness, arrhythmia, orthostatic hypotension, and carotid sinus hypersensitivity...

... Background and purpose Management of antihypertensive therapy is challenging in patients with symptomatic orthostatic hypotension, a population often excluded from randomised controlled trials of antihypertensive therapy. In this systematic review and meta-analysis, we sought to determine whether...

... after standing. Orthostatic hypotension (OH) was defined as a drop in systolic BP of ≥20 mmHg and/or diastolic BP of ≥10 mmHg between the sitting and standing values [ 18 ]. Participants were asked if they were afraid of falling (yes/no); if yes, they were asked ‘do you feel somewhat afraid or very...

..., hypertension; OH-BP, classic orthostatic hypotension group; OHDAS, Orthostatic Hypotension Daily Activity Scale; OHSA, Orthostatic Hypotension Symptom Assessment; OH-Sx, orthostatic hypotension symptoms alone group; SBP, systolic blood pressure; w/o Sx, without orthostatic hypotension symptoms; w/Sx...

... ( https://creativecommons.org/licenses/by-nc/4.0/ ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] Abstract Background Orthostatic hypotension (OH...

... is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Introduction Many older people with orthostatic hypotension (OH) may not report...

... that it is the pathway through which the consequences of physical frailty develop ( 2 , 3 ). Orthostatic hypotension (OH), classically defined as a sustained drop of 20 mmHg systolic blood pressure (SBP) and/or 10 mmHg diastolic blood pressure (DBP) within 3 minutes of standing ( 4 ), is a common condition in older...

... such as neurodegeneration, atherosclerosis, deconditioning and polypharmacy. These changes commonly result in orthostatic hypotension, hypertension or both, and are consistently associated with multiple adverse outcomes. In this article, we discuss the healthy baroreflex, and physiological and pathophysiological reasons...