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Photo-modulation of Actin Filaments using Spiropyran-Modified Peptide Nanofibers
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Subhajit Guria and others
Bulletin of the Chemical Society of Japan, uoaf045, https://doi.org/10.1093/bulcsj/uoaf045
Published: 16 May 2025
...:https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Modulating actin filament dynamics is crucial to understanding actin-mediated cellular processes and controlling cell functions artificially. This study developed a novel photoresponsive spiropyran (SP)/merocyanine (MC)-modified self-assembling peptide...
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Modulating the local microenvironment over isolated nickel sites through first-shell coordination to regulate the reaction pathway of CO2 electroreduction Open Access
Yan Kong and others
National Science Review, nwaf173, https://doi.org/10.1093/nsr/nwaf173
Published: 06 May 2025
... the reaction pathways of single-atom catalysts. Modulating the local microenvironment around single-atom sites is anticipated to steer the reaction pathway in CO2 reduction reaction. By specifically altering the coordination shell of boron around the Ni atoms, a Ni single-atom catalyst achieved...
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Investigating the Role of Vitamin D in the Prevention and Control of Dengue Virus Vectors and Related Diseases: A Systematic Review Study
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Ebrahim Abbasi
Epidemiologic Reviews, mxaf006, https://doi.org/10.1093/epirev/mxaf006
Published: 02 May 2025
... PubMed, Web of Science, and Scopus. Inclusion criteria encompassed studies examining the association between vitamin D and dengue virus infection, disease severity, and immune modulation. Results: Six studies met the inclusion criteria. Findings indicated that vitamin D supplementation reduced pro...
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TT-Nb2O5 with dual-band modulation and exceptional performance retention for fast-responsive electrochromics Open Access
Qingjiao Huang and others
National Science Review, nwaf154, https://doi.org/10.1093/nsr/nwaf154
Published: 24 April 2025
... medium, provided the original work is properly cited. Abstract Independently modulating the transmittance of solar spectra, specifically within the visible and near-infrared light ranges, presents a significant prospect for windows to effectively manage lighting and energy consumption in both buildings...
Journal Article
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A multifunctional Dihydromyricetin-loaded hydrogel for the sequential modulation of diabetic wound healing and Glycemic control Open Access
Hongyi Li and others
Burns & Trauma, tkaf024, https://doi.org/10.1093/burnst/tkaf024
Published: 19 March 2025
... conducive to wound repair. Comprehensive in vitro and in vivo analyses corroborate the multifaceted therapeutic capabilities of DPFI, including its antibacterial activity and abilities to clear ROS, reduce inflammation, promote angiogenesis, promote epithelialization, and modulate blood...
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Combination Therapy Dramatically Promotes Remyelination Open Access
Yawen Li and others
Journal of Molecular Cell Biology, mjaf005, https://doi.org/10.1093/jmcb/mjaf005
Published: 28 February 2025
... to prevent disease progression due to their inability to actively promote remyelination. Small molecules have been reported to promote myelin regeneration but their therapeutic efficacy is limited by insufficient immune modulation. Thus, the strategies achieving both immunomodulation and active myelin...
Journal Article
Use of biotics in animals: impact on nutrition, health, and food production Open Access
Kelly S Swanson and others
Journal of Animal Science, Volume 103, 2025, skaf061, https://doi.org/10.1093/jas/skaf061
Published: 27 February 2025
... in science may improve biotic development in the future. animal health antimicrobial resistance food safety gastrointestinal health immune modulation Probiotics ( Hill et al., 2014 ), prebiotics ( Gibson et al., 2017 ), synbiotics ( Swanson et al., 2020 ), and postbiotics ( Salminen et al., 2021...
Journal Article
EVENAMIDE AS ADD-ON TREATMENT FOR PATIENTS WITH CHRONIC SCHIZOPHRENIA NOT RESPONDING ADEQUATELY TO THEIR CURRENT ANTIPSYCHOTIC MEDICATION: RESULTS OF A POTENTIALLY PIVOTAL, PHASE II/III, INTERNATIONAL, RANDOMIZED, DOUBLE BLIND, PLACEBO- CONTROLLED TRIAL Open Access
*Ravi Anand and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i350–i351, https://doi.org/10.1093/ijnp/pyae059.625
Published: 12 February 2025
... (2018) T48. Antipsychotic efficacy of evenamide (NW-3509) is due to modulation of glutamatergic dysregulation. Schizophr Bull 44(Suppl 1):S132. doi: 10.1093/schbul/sby016.324. 9.Anand R, Forrest EC, Hartman RD, Graham SM, Faravelli L (2017) Evenamide, a voltage-gated sodium channel blocker...
Journal Article
EVENAMIDE, AS AN ADD-ON TO ANTIPSYCHOTICS, PRODUCES LONG- LASTING CLINICALLY MEANINGFUL BENEFIT AND CONVERTS TREATMENT- RESISTANT SCHIZOPHRENIA (TRS) PATIENTS INTO A RESPONSIVE STATE: 6-MONTH RESULTS FROM AN ONGOING INTERNATIONAL RANDOMIZED STUDY Open Access
*Ravi Anand and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i352–i353, https://doi.org/10.1093/ijnp/pyae059.627
Published: 12 February 2025
... and associated with long-term efficacy. SIRS 2023-poster. 7.Anand, R., Turolla, A., Chinellato, G., Roy, A., & Hartman, R. D. (2023). Phase 2 results indicate evenamide, a selective modulator of glutamate release, is associated with clinically important long-term efficacy when added to an antipsychotic...
Journal Article
EVENAMIDE AS ADD-ON TREATMENT FOR TREATMENT-RESISTANT SCHIZOPHRENIA (TRS) PATIENTS NOT BENEFITING FROM ANTIPSYCHOTICS: DESIGN OF A PHASE 3, POTENTIALLY PIVOTAL, INTERNATIONAL, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIAL Open Access
*Ravi Anand and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i353–i354, https://doi.org/10.1093/ijnp/pyae059.628
Published: 12 February 2025
...-A, CDSS, and C-SSRS. Results The results of the study will demonstrate if addition of evenamide to patients with TRS on APs is associated with efficacy and tolerability. Discussion & Conclusions Results from this study will determine if glutamate modulation by evenamide may represent a new...
Journal Article
A phloem-limited RNA phytovirus infection does not positively modulate vector preference and fitness in primary and alternate hosts Open Access
Sudeep Pandey and others
Environmental Entomology, Volume 54, Issue 2, April 2025, Pages 341–351, https://doi.org/10.1093/ee/nvaf005
Published: 04 February 2025
... in the transmission of RNA phytoviruses in the family Solemoviridae. According to “host manipulation hypothesis,” phloem limited and persistently transmitted Solemoviridae viruses modulate host physiology that positively affects vector behavior and fitness and facilitates virus spread...
Journal Article
Unconventional approaches for the induction of microbial natural products Open Access
Bathini Thissera and others
Journal of Applied Microbiology, Volume 136, Issue 1, January 2025, lxaf014, https://doi.org/10.1093/jambio/lxaf014
Published: 10 January 2025
... such as quorum sensing, epigenetic modulation, and ribosome engineering. Whenever applicable, we will also discuss their mechanisms and optimizations to improve the microbial drug discovery process. induction of microbial natural products quorum sensing epigenetic modulation ribosome engineering Impact...
Journal Article
Cardiac contractility modulation as bailout in a patient with phospholamban p.Arg14del related cardiomyopathy intolerant to medication: a case report Open Access
Faro R Verelst and others
European Heart Journal - Case Reports, Volume 9, Issue 1, January 2025, ytae687, https://doi.org/10.1093/ehjcr/ytae687
Published: 08 January 2025
... with a PLN-related cardiomyopathy treated with CCM. Cardiac contractility modulation therapy is a novel device therapy, which gives a non-excitatory high-voltage electrical signal during the refractory period. Randomized controlled trials prove a benefit of CCM on exercise capacity, QoL and LVEF. 1–3...
Journal Article
Field integration of shoot gas-exchange and leaf chlorophyll fluorescence measurements to study the long-term regulation of photosynthesis in situ Open Access
Jaakko Oivukkamäki and others
Tree Physiology, Volume 45, Issue 1, January 2025, tpae162, https://doi.org/10.1093/treephys/tpae162
Published: 11 December 2024
... module. In this communication we provide a first-time demonstration of long-term, in situ and combined measurements of photosynthetic gas-exchange and ChlF. We do so by integrating a new miniature pulse amplitude modulated-fluorometer into an existing system of automated chambers to track photosynthetic...
Journal Article
Effect of a dietary nutraceutical “STRUCTURE-Joint” on response of horses to intra-articular challenge with IL-1: implications for tissue adaptation to stress Open Access
Lindsay Korac and others
Translational Animal Science, Volume 8, 2024, txae172, https://doi.org/10.1093/tas/txae172
Published: 07 December 2024
... bilirubin, and decrease in plasma glucose. These data provide evidence for the usefulness of ST-J to modulate physiological variables with importance in exercise performance and tissue adaptation to exercise stress and further research on this product is warranted. This study demonstrates that the dietary...
Journal Article
Cortical tracking of speakers’ spectral changes predicts selective listening
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Francisco Cervantes Constantino and Ángel Caputi
Cerebral Cortex, Volume 34, Issue 12, December 2024, bhae472, https://doi.org/10.1093/cercor/bhae472
Published: 04 December 2024
... by parallel processing of vocal spectral contours from speech sounds, but it has not yet been established how this occurs in the brain’s cortex. We investigate single-trial neural tracking of slow frequency modulations in speech using electroencephalography. Participants briefly listened to unfamiliar single...
Journal Article
A highly visible-transparent thermochromic smart window with broadband infrared modulation for all-season energy savings Open Access
Yi Jiang and others
National Science Review, Volume 12, Issue 2, February 2025, nwae408, https://doi.org/10.1093/nsr/nwae408
Published: 13 November 2024
... modulation including the transmission of visible (TVis) and near-infrared (TNIR) light, and the emissivity of mid-infrared (εMIR) light in response to ambient temperature change. However, thermochromic windows that maintain high TVis while modulating...
Journal Article
Noninvasive brain stimulation beyond the motor cortex: a systematic review and meta-analysis exploring effects on quantitative sensory testing in clinical pain Open Access
Andrew Flood and others
Pain Medicine, Volume 26, Issue 2, February 2025, Pages 98–111, https://doi.org/10.1093/pm/pnae103
Published: 15 October 2024
.... As chronic pain is associated with pain hypersensitivity and impaired endogenous descending pain modulation, it is plausible that non-M1 NIBS promotes analgesic effects by influencing these processes. Objective The aim of this systematic review and meta-analysis was therefore to evaluate the effect...
Journal Article
Yawning in sync: implications for social cohesion in horses Open Access
Alice Galotti and others
Current Zoology, Volume 71, Issue 2, April 2025, Pages 137–151, https://doi.org/10.1093/cz/zoae052
Published: 16 September 2024
... 21 05 2024 10 09 2024 14 10 2024 EquiFACS Equus caballus social modulation hypothesis Yawn contagion yawn morphologies © The Author(s) 2024. Published by Oxford University Press on behalf of Editorial Office, Current Zoology. 2024 This is an Open Access article distributed...
Journal Article
PSVIII-15 Inoculating suckling beef calves with a bovine-derived blend of Lactobacillus spp. exhibited psychobiotic potential for stress mitigation Free
Vanesa Ramirez-Sepulveda and others
Journal of Animal Science, Volume 102, Issue Supplement_3, September 2024, Pages 581–582, https://doi.org/10.1093/jas/skae234.654
Published: 14 September 2024
..., this study evaluated the impacts of administering a bovine-derived mixture of Lactobacillus spp. during early life to beef calves as a strategy to modulate long-term gut microbiota and potentially alleviate weaning stress. Crossbred beef calves [n = 32; 66 ± 11 kg of body weight (BW); 60 ± 6 d...
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