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Journal Article
A landmark federal interagency collaboration to promote data science in health care: Million Veteran Program-Computational Health Analytics for Medical Precision to Improve Outcomes Now
Amy C Justice and others
in
JAMIA Open
JAMIA Open, Volume 7, Issue 4, December 2024, ooae126, https://doi.org/10.1093/jamiaopen/ooae126
Published: 06 November 2024
..., the Department of Veterans Affairs (VA) and the Department of Energy (DOE) established an Interagency Agreement (IAA), the Million Veteran Program-Computational Health Analytics for Medical Precision to Improve Outcomes Now (MVP-CHAMPION) research collaboration. Materials and Methods Oversight fell under...
Journal Article
Quantifying the HIV reservoir with dilution assays and deep viral sequencing
Sarah C Lotspeich and others
in
Biometrics
Biometrics, Volume 80, Issue 1, March 2024, ujad018, https://doi.org/10.1093/biomtc/ujad018
Published: 16 February 2024
.... Eliminating these reservoirs is the goal of HIV cure research. The quantitative viral outgrowth assay (QVOA) is commonly used to estimate the reservoir size, that is, the infectious units per million (IUPM) of HIV-persistent resting CD4+ T cells. A new variation of the QVOA, the ultra deep sequencing assay...
Journal Article
Deep sequential neural network models improve stratification of suicide attempt risk among US veterans
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Carianne Martinez and others
Journal of the American Medical Informatics Association, Volume 31, Issue 1, January 2024, Pages 220–230, https://doi.org/10.1093/jamia/ocad167
Published: 28 September 2023
...Carianne Martinez; Drew Levin; Jessica Jones; Patrick D Finley; Benjamin McMahon; Sayera Dhaubhadel; Judith Cohn; Million Veteran Program; MVP Suicide Exemplar Workgroup; David W Oslin; Nathan A Kimbrel; Jean C Beckham A full list of members and their affiliations appears in the Supplementary...
Journal Article
PhenoMIP: High-Throughput Phenotyping of Diverse Caenorhabditis elegans Populations via Molecular Inversion Probes
Calvin Mok and others
G3 Genes|Genomes|Genetics, Volume 10, Issue 11, 1 November 2020, Pages 3977–3990, https://doi.org/10.1534/g3.120.401656
Published: 01 November 2020
... strains of the Million Mutation Project (MMP) and the wild isolates of the Caenorhabditis elegans Natural Diversity Resource (CeNDR) there are now many sequenced alleles across the C. elegans genome that could prove informative to deciphering the roles in organismal fitness...
Journal Article
Validation of the Oxford WebQ Online 24-Hour Dietary Questionnaire Using Biomarkers
Darren C Greenwood and others
American Journal of Epidemiology, Volume 188, Issue 10, October 2019, Pages 1858–1867, https://doi.org/10.1093/aje/kwz165
Published: 18 July 2019
... and the extent to which statistical power to detect these comparisons is reduced even in large-scale studies such as the UK Biobank study and the Million Women Study. Participants were enrolled in a United Kingdom study designed to validate both the Oxford WebQ dietary assessment tool and the myfood24 dietary...
Journal Article
Electronic clinical quality measure reporting challenges: findings from the Medicare EHR Incentive Program’s Controlling High Blood Pressure Measure
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Dawn M Heisey-Grove and others
Journal of the American Medical Informatics Association, Volume 25, Issue 2, February 2018, Pages 127–134, https://doi.org/10.1093/jamia/ocx049
Published: 19 May 2017
... for this largely preventable condition. 1 Hypertension is a major contributor to cardiovascular disease that can be controlled with lifestyle modifications and medications. Yet, of the 70 million American adults with hypertension, only about half have controlled hypertension. 3 To address...
Journal Article
Caenorhabditis elegans DAF-2 as a Model for Human Insulin Receptoropathies
David A Bulger and others
G3 Genes|Genomes|Genetics, Volume 7, Issue 1, 1 January 2017, Pages 257–268, https://doi.org/10.1534/g3.116.037184
Published: 01 January 2017
... an analytic bottleneck. Insulin-like signaling in Caenorhabditis elegans has long provided a model to assess consequences of human insulin signaling mutations, but this has not been evaluated in the context of current genetic tools. We have exploited strains derived from the Million Mutation Project...
Includes: Multimedia
Journal Article
Relationship of Height to Site‐Specific Fracture Risk in Postmenopausal Women
Miranda EG Armstrong and others
Journal of Bone and Mineral Research, Volume 31, Issue 4, 1 April 2016, Pages 725–731, https://doi.org/10.1002/jbmr.2742
Published: 17 November 2015
...Miranda EG Armstrong; Oksana Kirichek; Benjamin J Cairns; Jane Green; Gillian K Reeves; Valerie Beral for the Million Women Study Collaborators MILLION WOMEN STUDY FRACTURE HEIGHT PROSPECTIVE STUDIES POSTMENOPAUSAL ABSTRACT Height has been associated with increased risk of fracture...
Journal Article
Childbearing, breastfeeding, other reproductive factors and the subsequent risk of hospitalization for gallbladder disease
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Bette Liu and others
International Journal of Epidemiology, Volume 38, Issue 1, February 2009, Pages 312–318, https://doi.org/10.1093/ije/dyn174
Published: 05 September 2008
...Bette Liu; Valerie Beral; Angela Balkwill; on behalf of the Million Women Study Collaborators *Corresponding author. Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Roosevelt Drive, Oxford OX3 7LF, UK. E-mail: [email protected] 28 7 2008 Published by Oxford...
Journal Article
Relationship of height, weight and body mass index to the risk of hip and knee replacements in middle-aged women
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B. Liu and others
in
Rheumatology
Rheumatology, Volume 46, Issue 5, May 2007, Pages 861–867, https://doi.org/10.1093/rheumatology/kel434
Published: 04 February 2007
...B. Liu; on behalf of the Million Women Study Collaborators; A. Balkwill; on behalf of the Million Women Study Collaborators; E. Banks; on behalf of the Million Women Study Collaborators; C. Cooper; on behalf of the Million Women Study Collaborators; J. Green; on behalf of the Million Women Study...
Journal Article
Ambient Air Pollution and Asthma Exacerbations in Children: An Eight-City Analysis
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Jonathan S. Schildcrout and others
American Journal of Epidemiology, Volume 164, Issue 6, 15 September 2006, Pages 505–517, https://doi.org/10.1093/aje/kwj225
Published: 23 June 2006
... million Many recent panel studies of the relation between air pollution concentrations and asthma aggravation in children have shown positive associations. Of the Environmental Protection Agency's six criteria pollutants, particulate matter and ozone have exhibited the most evidence of associations...
Journal Article
Association of Higher Levels of Ambient Criteria Pollutants with Impaired Cardiac Autonomic Control: A Population-based Study
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Duanping Liao and others
American Journal of Epidemiology, Volume 159, Issue 8, 15 April 2004, Pages 768–777, https://doi.org/10.1093/aje/kwh109
Published: 15 April 2004
... is associated with CVD. air pollution; cardiovascular diseases; heart rate Abbreviations: AIRS, Aerometric Information Retrieval System; ARIC, Atherosclerosis Risk in Communities; HRV, heart rate variability; PM10, particulate matter less than 10 µm in aerodynamic diameter; ppm, parts per million; SD...
Journal Article
Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague–Dawley rats
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Clinton D. Allred and others
Carcinogenesis, Volume 25, Issue 2, February 2004, Pages 211–218, https://doi.org/10.1093/carcin/bgg198
Published: 01 February 2004
.... BrdU, bromo-deoxyuridine ERα, estrogen receptor α HRT, hormone replacement therapy MNU, 1-methyl-1-nitrosourea p.p.m., parts per million PR, progesterone receptor The use of dietary supplements for therapeutic purposes has increased in popularity over the past several years. One area of interest...
Journal Article
Acute and chronic arsenic toxicity
R N Ratnaike
Postgraduate Medical Journal, Volume 79, Issue 933, July 2003, Pages 391–396, https://doi.org/10.1136/pmj.79.933.391
Published: 01 July 2003
... under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Arsenic toxicity is a global health problem affecting many millions of people. Contamination is caused by arsenic from natural geological...
Journal Article
All in the family: the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases
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Kelly G. Ten Hagen and others
in
Glycobiology
Glycobiology, Volume 13, Issue 1, January 2003, Pages 1R–16R, https://doi.org/10.1093/glycob/cwg007
Published: 01 January 2003
...-linked oligosaccharides UDP GalNAc:polypeptide N-acetylgalactosaminyl-transferases UDP GalNAc CHO, Chinese hamster ovary ER, endoplasmic reticulum GT1, glycosyltransferase motif 1 LDL, low-density lipoprotein MYA, million years ago ppGaNTase, UDP-N-acetylgalactosamine:polypeptide N...
Journal Article
Proton MR spectroscopy with metabolite-nulling reveals elevated macromolecules in acute multiple sclerosis
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I. Mader and others
in
Brain
Brain, Volume 124, Issue 5, May 2001, Pages 953–961, https://doi.org/10.1093/brain/124.5.953
Published: 01 May 2001
... = myo-inositol NAA = N-acetyl-aspartate p.p.m. = parts per million STEAM = stimulated echo acquisition mode TE = echo time TEeff = effective echo time TI = inversion time TM = mixing time TR = repetition time VOI = volume of interest Abstract Proton magnetic resonance...
Journal Article
Clinical information for research; the use of general practice databases
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R Lawrenson and others
Journal of Public Health, Volume 21, Issue 3, September 1999, Pages 299–304, https://doi.org/10.1093/pubmed/21.3.299
Published: 01 September 1999
... available databases are the General
between 1.8 and 4 million patients. Despite their availability
only limited use has been made of them for epidemiological Practice Research Database (GPRD), the MediPlus database
and health service research purposes. They are a unique and the Doctors Independent...
Journal Article
Inhaled nitric oxide in cardiology practice
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Christopher S Hayward and others
Cardiovascular Research, Volume 43, Issue 3, August 1999, Pages 628–638, https://doi.org/10.1016/S0008-6363(99)00114-5
Published: 15 August 1999
..., Parts per million, cGMP, Guanosine 3′,5′-cyclic monophosphate GC, Guanylate cyclase MetHb, Methaemoglobin NOHb, Nitrosyl-haemoglobin ARDS, Adult respiratory distress syndrome PVR, Pulmonary vascular resistance LVAD, Left ventricular assist device Time for primary review 42 days. One of the most...
Chapter
Playing the Lottery for Marriage and Profit
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Amy M. Froide
Published: 13 October 2016
... private to State lotteries and in the process transformed from gamblers to investors. These schemes proved so popular that there were twenty-eight State Lotteries between 1694 and 1750. 4 The first foray by the State into the lottery business was the Million Adventure. The government hired...
Chapter
An American Plan
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Matthew Dallek
Published: 01 August 2016
... Voluntary Service: Lady Stella Reading social defense volunteers/volunteerism 50 million women In order to realize [victory in the war] all sorts of activities are set going, arrangements made, organizations instituted, as incidental means. After they have been called into being they cannot be whisked...
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