... with overweight or obesity. Discontinuing CS was linked to reductions in WC. These findings underscore the need to carefully assess chronic systemic and local CS use, as discontinuation could benefit obesity-related outcomes in certain patients. glucocorticoids body weight waist circumference corticosteroids...

... included. During the prescribed glucocorticoid tapering regimen, 76/353 had a 9 am serum cortisol check after ruling out relapsing disease. 34/76 had a serum cortisol >350 nmol/l (our laboratory cut off for adequacy of adrenal reserve). 7/76 had a serum cortisol of < 100 nmol/l, indicative...

... they respond to ecological changes or anthropogenic disturbances. However, preservation techniques to prevent hormone alteration can be problematic, and not all are field friendly. We compared five processing methodologies to preserve samples for faecal glucocorticoid, progestagen and thyroid hormone...

... through chronotherapy, exploring its potential to enhance therapeutic outcomes while minimizing adverse effects. Graphical abstract Graphical abstract circadian rhythm chronotypes chronobiology pharmacotherapy hormone replacement glucocorticoids ACCEPTED MANUSCRIPT 1 The Chronobiology of Hormone...

..., and reproduction in any medium, provided the original work is properly cited. Abstract Objectives It is unknown to what extent updated treatment recommendations regarding glucocorticoids (GC) and hydroxychloroquine (HCQ) for patients with systemic lupus erythematosus (SLE) have been incorporated into clinical...

... of the determinants of this raised BP as well as its long-term effects. blood pressure congenital adrenal hyperplasia glucocorticoids statistical modeling Bayesian analysis National Institute for Health and care Research 10.13039/501100000272 NIHR302559 Cancer Research UK programme C49297/A27294...

... rheumatica prednisolone glucocorticoids diagnostic accuracy diagnostic taper Danish Rheumatism Association, Independent Research Fund Denmark Rheumatology key messages No study has previously investigated the impact of prednisolone on the clinical assessment of PMR. The clinical assessment of PMR...

... discontinuation without a shared decision with their health care providers can result in more harm than good. Thus, there is a need for an evidence-based protocol for drug withdrawal. Currently, long-term remission allows glucocorticoid (GC) withdrawal, as studies have shown its feasibility and safety...

... days before and 180 days after glucocorticoid initiation. Rates of concomitant immunosuppressive therapies and PJP prophylaxis were compared across groups. Statistical analyses were performed using STATA/MP18.0 software, and results are reported per STROBE guidelines. The requirement for ethical review...

... of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) ANCA-associated vasculitis treatment abatacept avacopan glucocorticoids infection vaccination AstraZeneca 10.13039/100004325 GSK 10.13039/100004330 Union...

...:https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Polymyalgia rheumatica (PMR) is a common inflammatory disorder affecting individuals over 50. The cornerstone of PMR treatment remains oral glucocorticoids (GCs), with initial doses tailored to the risk of relapse and comorbidities. However...

.... Methods We identified patients with SLE from the National Database of Health Insurance Claims of anonymized health insurance-related information; they had disease names associated with SLE and were treated with glucocorticoids, hydroxychloroquine, or immunosuppressants. These data were used...

... in the general population [ 10 ]. In patients with giant cell arteritis, glucocorticoid use and older age are predictors of anxiety and depression [ 11 ]. Depression is also associated with a higher risk of adverse health outcomes, including increased disease activity and pain perception [ 12 , 13...

... 8.5 (3.0-13.0) 7.5 (3.0-11.5) 9.5 (6.0- 13.0) Glucocorticoid dose, mg/m²/d 12.5 (8.2-35.7) 12.0 (8.2-21.9) 12.3 (8.5-35.7) Testosterone  % within range 88 82 95  % below range 4 7 0  % above range 8 11 5 17OH progesterone...

... (BICLA) response. The proportion of patients who tapered their glucocorticoid (GC) dose throughout the study, without increasing their dose, or who sustained baseline GC doses of ≤7.5 mg/day was numerically higher in the anifrolumab group [78.9% (15/19)] than in the placebo group [50.0% (7/14...

..., providing energy for the organism to respond to environmental perturbations. Cortisol, the predominant glucocorticoid (GC) in most mammals, is metabolized by the liver and excreted as FCMs. For FCMs to serve as a meaningful physiological index of stress in brown bears (Ursus arctos), we sought...

... Society ( 16 ). The patients with CS were studied twice: first, in the active phase of the disease, and second, 1 to 2 years after being in biochemical remission following first-line surgical treatment. Following successful surgery, all patients with CS received standard glucocorticoid replacement therapy...

... Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) hypophysitis glucocorticoids sarcoidosis pituitary deficiency Comment on “Evaluation and follow-up of patients diagnosed with hypophysitis: a cohort study” by Hacioglu et al. doi: https://doi.org/10.1093...

... is to reduce the risk of progression to ESKD. Glucocorticoids have been the cornerstone of LN therapy for decades, with early studies demonstrating their potential to prevent progression to ESKD [ 5–7 ]. However, optimal strategies for glucocorticoid use in LN—regarding administration [intravenous (IV) pulses...

.../pages/standard-publication-reuse-rights ) hypophysitis glucocorticoids primary hypophysitis observation sarcoidosis We would like to thank Miquel et al. ¹ for their comments, and for the opportunity to further discuss the methodology and the results of our study. ² Miquel et...