... at a depth of 5.4 and 8 km of Mars, providing the first seismic evidence of liquid water at the base of Mars' upper crust. Mars Liquid water Upper crust Low-velocity zone Receiver function inversion O RIGIN A L U N EDITED M AN U SCRIPT 1 RESEARCH ARTICLE 2 EARTH SCIENCES 3 4 Seismic evidence of liquid...

...:https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Inherited erythromelalgia, small fiber neuropathy and paroxysmal extreme pain disorder are caused by gain-of-function mutations in the voltage gated sodium channel Nav1.7. How different mutations in the same channel enhancing electrogenesis...

...-rights ) Abstract Background Bothersome lower urinary tract symptoms (LUTS) can negatively affect the quality of life in women, including sexual function. Aim The primary aim of the study was to explore the association between LUTS severity and sexual functioning among women with LUTS. Methods...

... predictive performance for 1-year progression of kidney function with an AUC of 0.906 in the internal validation set and 0.768 in the external validation set. The final predictive model incorporating only nine variables has been implemented into a web application to enhance its usability in clinical settings...

... been lacking. We aim to understand the functions of circSLC8a1 and its translated protein in cardiac remodeling. Methods and Results To elucidate the functional significance of circSLC8a1, we established a transgenic mouse line expressing circSLC8a1 and its translated protein SLC8a1-604. We present...

... for Health and Care Excellence and the latest from the American Society of Reproductive Medicine do not recommend routine testing. This paper outlines the discourse and varied recommendations related to routine thyroid function testing, with specific reference to the subfertile population of women...

..., collected through the end of 2023, we identify a pure sample of 146 Type II GRBs. With this sample, we construct the luminosity function (LF) using both the Broken Power Law (BPL) and Triple Power Law (TPL) models. Our results indicate that, similar to LGRBs, a strong redshift evolution in either luminosity...

... that offer new avenues for research, and then explore the applications of CRISPR technology in large-scale genetic screening, lineage tracing, genetic diagnosis, and gene therapy. As this technology evolves, it holds significant promise for studying gene functions and treating human diseases in the near...

... the load associated with a certain deformation. However, in cylinder–cylinder contacts, algebraic formulas exist only for determining the deformation of the cylinders in response to an external load. Accordingly, this study uses the Lambert W-function to derive an algebraic formula for computing the load...

.... However, previous studies have shown mixed results. We investigated associations between grandchild caregiving and cognitive function among 5,005 older adults (Cohort 1) and 1,521 middle-aged adults (Cohort 2). Cognitive functioning was measured by the Short Portable Mental Status Questionnaire...

... expenditure. Obesity Adipose tissue function Adaptive thermogenesis Fatness Weight gain ACCEPTED MANUSCRIPT 1 Baseline body fat percentageis associated to weight and fat mass gain fromhigh-fat overfeeding 2 over 8 weeks 3 4 Jose E. Galgani1,2,3 Rodrigo Fernández-Verdejo3,4, George A. Bray3, Steven R...

... that 20 percent of pediatric massive burn survivors experience impairment in long-term physical function and psychosocial distress.¹ Pediatric patients from the United States and Mexico with major burns likely receive similar care during the initial hospitalization given that many US burn...

... thrombus formation. Additionally, they induce hemolysis, alter red blood cell morphology, and impair immune cell functions, including those of macrophages and lymphocytes, by modulating cytokine secretion and inflammatory responses. Understanding these mechanisms is essential for devising effective public...

... that allows us to identify at which cosmic time galaxies are more efficient at forming stars. For low-mass star-forming galaxies, the SFRD as a function of stellar mass can be straightforwardly related to the galaxy stellar mass function (GSMF). Given the uncertainty of the GSMF at the low-mass end, due...

... the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT We characterize the rest-frame 1500 Å UV luminosity function (UVLF...

... the original work is properly cited. Abstract Understanding the processes that transform star-forming galaxies into quiescent ones is key to unraveling the role of environment in galaxy evolution. We present measurements of the luminosity functions (LFs) and stellar mass functions (SMFs) of passive red...

... on cognitive health of older Chinese. Results The findings indicate that the LCCP program has been associated with relative improvements in cognitive function of older adults in China, and that this observed positive association has increased over time. Mechanism analysis identifies the enhanced outdoor...

... Accepted Manuscript Brain resting-state functional connectivity mediates the age-associated decline in physical activity engagement Meishan Ai, PhD,1,3, Emma M. Tinney, MSc,1,3, Goretti España-Irla, PhD,2,3, Charles H. Hillman, PhD,2,3, Arthur F. Kramer, PhD,1,3, Timothy P. Morris, PhD,2,3 1Department...

... observed with walking alone. Conclusions Twelve weeks of low-volume HIIT training can improve glucose control and induces adaptations in skeletal muscle important for metabolic health in individuals with prediabetes. exercise HIIT insulin sensitivity prediabetes mitochondrial function...

... be challenging given that the tools are often time-consuming, and the diagnosis is not always directly actionable given that it can encompass multiple systemic deficits. Assessments of physical function, a component of frailty, may be more pragmatic for routine screening because they are generally less...