... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background Although several growth factors have been implicated in alcohol dependence (AD) [1], fibroblast growth factor 2 (FGF2) was hypothesized...

... in relation to alcohol dependence (AD) [1]. Its binding to TNF receptor 1 (TNFR1) has also been reported to be involved in the apoptosis pathway [2] and to lead to neuronal cell death. Delirium tremens (DT) is a serious subtype of AWS and associated with high mortality if inadequately treated. Little is known...

... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background Delirium tremens (DTs) is the most serious complication of alcohol withdrawal syndrome in patients with alcohol dependence (AD...

...*Shinya Kasai; Daisuke Nishizawa; Susumu Higuchi; Kazutaka Ikeda alcohol dependence endogenous opioid genetic variation proopiomelanocortin © The Author(s) 2025. Published by Oxford University Press on behalf of CINP. 2025 This is an Open Access article distributed under the terms...

... hormone alcohol dependence sex-specific differences principa components Abstracts CINP2024 by non-DT group (24.0 ± 22.4 pg/mL) and then control group (11.8 ± 6.1 pg/mL) (p 0.05). In males, the first PC (PC1) that accounted for the majority of data variance was significantly associated with AD (p=0.016...

... the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background Alcohol Withdrawal Syndrome (AWS) is one of the defining characteristics of alcohol dependence (AD) and can manifest with various clinical features, including delirium...

... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background Alcohol dependence (AD) is a complex disorder with unclear underlying etiologies. One strategy to understand its pathophysiology involves...

... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background Alcohol is a significant modulator of the immunocytokine system. Alcohol dependence (AD) can lead to a range of psychological and physical...

... intervention for supporting individuals with alcohol dependence who may experience barriers to engaging with specialist alcohol treatment services. This qualitative study explored determinants to the successful and sustainable implementation of AAOT. Findings can support the development of AAOT services, new...

...Huanfen Li; Lifang Zhu; Jie Zhang; Jun Xue prevalence underweight alcohol dependence In general population surveys, alcohol dependence is associated with a 2-fold higher risk of all-cause mortality risk in men than in non-alcohol-dependent individuals ( Roerecke and Rehm 2013 ). In addition...

... alcohol dependence Deutsche Forschungsgemeinschaft 10.13039/501100001659 402170461—TRR265 270949263/GRK2162 Alcohol use disorder (AUD) represents an important public health issue. It broadly burdens the affected individuals, their relatives, and the society in general. A major problem is the often...

... alcohol dependence alcohol-related liver disease randomized-controlled trial ClinicalTrials.gov Identifier: NCT03879759 Abstract N-acetyl cysteine (NAC) is a potent antioxidant that modulates glutamatergic signalling which is thought to play a role in alcohol use disorder (AUD). There have been...

... magnetic resonance imaging, this study investigated changes in the brain functioning of alcohol-dependent patients with and without depression. Alcohol-dependent patients (n = 48) and healthy controls (n = 31) were recruited. The alcohol-dependent patients were divided into those...

...-overarching changes in brain tissue in male AUD patients compared with controls, with similar changes in blood, making CpG-4 an interesting target as a possible biomarker for altered reward signaling. addiction alcohol dependence biomarker brain epigenetic GABA receptor B Using an in-silico prediction...

.... Conclusions Heightened pain sensitivity was observed following withdrawal from chronic ethanol exposure, and histone deacetylase inhibitors could be novel treatments for this alcohol withdrawal-induced hyperalgesia. pain SAHA alcohol dependence There is a complex relationship between alcohol and pain...

... by the regional ethical board at University of Gothenburg (No: 487-03). In this study, 349 participants were included. Of these, 24.6% were women and 75.4% were men. Their mean age was 47.8 ± 10.3 (women: 47.4 ± 10.6; male: 48 ± 10.3). Ninety-three percent fulfilled the DSM-IV criteria for alcohol dependence...

... variants genetic heterogeneity population stratification alcohol dependence The within-family and between-family tests of FGRF (i.e., FGRF-W and FGRF-B) evaluate the gene–phenotype association separately. We can combine these two sources of information in a single test, for example, using...

... of policy measures do respondents consider most effective in preventing obesity—and how does this compare with policies implemented to fight tobacco and alcohol dependence? A total of 3,171 respondents from the USA (508 male, 474 female; aged 18–93 years), the UK (607 male, 609 female; 18–93 years...

... for the most crucial alterations in psychiatric populations, especially cognitive and emotional impairments, the study of olfactory processing may be a relevant approach to identify specific markers of alcohol dependence. The aim of this study was to propose the probable olfactory markers for alcohol...

... 2015 Abstract Chemosensory (olfaction–taste) dysfunctions are considered as reliable biomarkers in many neurological and psychiatric states. However, experimental measures of chemosensory abilities are lacking in alcohol-dependence (AD) and Korsakoff Syndrome (KS, a neurological complication of AD...