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Keywords: active zone
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Journal Article
Paroxysmal dystonia results from the loss of RIM4 in Purkinje cells
Hyuntae Kim and others
in
Brain
Brain, Volume 147, Issue 9, September 2024, Pages 3171–3188, https://doi.org/10.1093/brain/awae081
Published: 13 March 2024
...@oup.com. 2024 This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Full-length RIM1 and 2 are key components of the presynaptic active zone...
Journal Article
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Genetic regulation of central synapse formation and organization in Drosophila melanogaster
Juan Carlos Duhart and Timothy J Mosca
in
Genetics
Genetics, Volume 221, Issue 3, July 2022, iyac078, https://doi.org/10.1093/genetics/iyac078
Published: 02 June 2022
Journal Article
The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release
Mila M Paul and others
in
Brain
Brain, Volume 145, Issue 11, November 2022, Pages 3787–3802, https://doi.org/10.1093/brain/awac011
Published: 11 January 2022
... of RIMS1/RIM1 (Rab3-interacting molecule 1). RIM is an evolutionarily conserved multi-domain protein and essential component of presynaptic active zones, which is centrally involved in fast, Ca2+-triggered neurotransmitter release. How the CORD7 mutation affects synaptic function has remained...
Journal Article
Presynaptic accumulation of α-synuclein causes synaptopathy and progressive neurodegeneration in Drosophila
Jessika C Bridi and others
Brain Communications, Volume 3, Issue 2, 2021, fcab049, https://doi.org/10.1093/braincomms/fcab049
Published: 22 March 2021
... of the presynaptic active zone essential for its structural integrity and function. These α-syn-mediated presynaptic alterations resulted in impaired neuronal function, which triggered behavioural deficits in ageing Drosophila that occurred prior to progressive degeneration of dopaminergic neurons...
Journal Article
The biologically active zone in upland habitats at the Hanford Site, Washington, USA: Focus on plant rooting depth and biomobilization
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Sara Lovtang and others
Integrated Environmental Assessment and Management, Volume 14, Issue 4, 1 July 2018, Pages 442–446, https://doi.org/10.1002/ieam.4044
Published: 23 March 2018
... (https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights) This Brief Communication and the Sample et al. ( 2015 ) paper evaluate the biologically active zone in upland habitats at the Hanford Site. The Hanford Site (approximately 145 039 ha [560 mi2]) is located in southcentral...
Journal Article
Transmission, Development, and Plasticity of Synapses
Kathryn P Harris and J Troy Littleton
in
Genetics
Genetics, Volume 201, Issue 2, 1 October 2015, Pages 345–375, https://doi.org/10.1534/genetics.115.176529
Published: 02 October 2015
..., characterized by the addition of new varicosities and synaptic branches ( Schuster et al. 1996 ; Zito et al. 1999 ). Each varicosity (termed a synaptic bouton) contains spatially segregated active zones (AZs) that reside opposite a distinct cluster of glutamate receptors (GluRs...
Journal Article
Physical and functional interaction of the active zone protein CAST/ERC2 and the β-subunit of the voltage-dependent Ca2+ channel
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Shigeki Kiyonaka and others
The Journal of Biochemistry, Volume 152, Issue 2, August 2012, Pages 149–159, https://doi.org/10.1093/jb/mvs054
Published: 09 May 2012
... In the nerve terminals, the active zone protein CAST/ERC2 forms a protein complex with the other active zone proteins ELKS, Bassoon, Piccolo, RIM1 and Munc13-1, and is thought to play an organizational and functional role in neurotransmitter release. However, it remains obscure how CAST/ERC2 regulates...
Journal Article
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CAST and ELKS proteins: structural and functional determinants of the presynaptic active zone
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Yamato Hida and Toshihisa Ohtsuka
The Journal of Biochemistry, Volume 148, Issue 2, August 2010, Pages 131–137, https://doi.org/10.1093/jb/mvq065
Published: 24 June 2010
... The Authors 2010. Published by Oxford University Press on behalf of the Japanese Biochemical Society. All rights reserved 2010 Abstract Cytomatrix at the active zone-associated structural protein (CAST) was first purified from rat brain. It belongs to a protein family with the protein ELKS being its close...
Chapter
10 Nominal Structure
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Ronald W. Langacker
Published: 14 February 2008
.... When nominal and relational expressions combine grammatically, there is often a discrepancy between the nominal expression's profile and the entity which participates most directly in the relationship—its active zone with respect to that relationship. Noun classes have varying degrees of semantic...
Chapter
Neurotransmitter Release
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Peggy Mason
Published: 01 February 2017
...Oxford University Press The biochemical and physiological processes of neurotransmitter release from an active zone, a specialized region of synaptic membrane, are examined. Synaptic vesicles containing neurotransmitters are docked at the active zone and then primed for release by SNARE complexes...
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