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Keywords: Rats
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Journal Article
Corynanthe pachyceras K. Schum (Rubiaceae) boosts sexual behavior, improves sexual hormones/semen quality and, modulates oxidative stress in a rat model of age-induced hypogonadism: an experimental study
Aubrile Julie Ndomgang and others
Sexual Medicine, Volume 13, Issue 2, April 2025, qfaf033, https://doi.org/10.1093/sexmed/qfaf033
Published: 06 May 2025
...-related hypogonadic rat. Methods Thirty-six aged (17-19-months-old) male Wistar rats (n = 6/group) were randomly distributed into six groups and orally treated with either distilled water (10 mg/kg), Viagra (5 mg/kg), aqueous or ethanolic extracts of C. pachyceras (8 mg/kg or 50 mg/kg) within...
Journal Article
Enhanced intracranial aneurysm development in a rat model of polycystic kidney disease
Anne France Cayron and others
Cardiovascular Research, cvaf063, https://doi.org/10.1093/cvr/cvaf063
Published: 18 April 2025
... that make PKD patients more vulnerable to IA disease are still not completely understood. The PCK rat is a well-known PKD model and has been extensively used to study cyst development and kidney damage. Here, we used this rat model to study IA induction and vulnerability. Methods and results IAs were...
Journal Article
Vocalization and acoustic activity pattern of the Bolivian Bamboo Rat (Dactylomys boliviensis) from southwestern Amazon through passive acoustic monitoring
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Orlando Zegarra and José Luis Mena
Journal of Mammalogy, gyaf008, https://doi.org/10.1093/jmammal/gyaf008
Published: 15 April 2025
..., Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract The Bolivian Bamboo Rat (Dactylomys boliviensis)—a large arboreal rodent found in the western Amazon—is known for its distinctive vocalizations and frequent presence in bamboo...
Journal Article
A cholic acid–supplemented diet suppresses very-low-density lipoprotein secretion in rats in the presence of insulin
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Fumika Yokoyama and others
Bioscience, Biotechnology, and Biochemistry, zbaf041, https://doi.org/10.1093/bbb/zbaf041
Published: 20 March 2025
...) suppressed hepatic very-low-density lipoprotein (VLDL) secretion in rats. Dietary CA supplementation suppressed VLDL secretion in vivo in the presence of insulin. These results suggest that enterohepatic 12-hydroxylated bile acids further enhance insulin-induced suppression of hepatic VLDL secretion...
Journal Article
New selective androgen receptor modulator TEI-SARM2 improves muscle function in a Duchenne muscular dystrophy rat model
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Katsuyuki Nakamura and others
Human Molecular Genetics, Volume 34, Issue 10, 15 May 2025, Pages 852–863, https://doi.org/10.1093/hmg/ddaf028
Published: 28 February 2025
... rats (DMD rats) generated by CRISPR/Cas were used as a DMD model to exhibit age-dependent progressive muscle degeneration and pathophysiological features similar to DMD patients and more severe than those displayed by mdx mice. TEI-SARM2 is a non-steroidal, orally available selective androgen...
Journal Article
TAAR1 AGONISTS AS POTENTIAL ANTI-ADDICTION CANDIDATES: PRECLINICAL EVIDENCE
*Jun-Xu Li
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i4–i5, https://doi.org/10.1093/ijnp/pyae059.007
Published: 12 February 2025
...*Jun-Xu Li TAAR1 cocaine addiction rats RO5166017 Abstract Background TAAR1 represents an exciting new drug target for the development of medications to treat neuropsychiatric disorders, with most exciting discoveries coming from the positive clinical trials of TAAR1 agonist...
Journal Article
EFFECTS OF ATOMOXETINE ON THE MPFC OF SHRSP/EZO AS AN ADHD ANIMAL MODEL
*Hiroki Shikanai and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i116–i117, https://doi.org/10.1093/ijnp/pyae059.201
Published: 12 February 2025
...*Hiroki Shikanai; Naoya Suzuki; Satoshi Shinozuka; Takeru Isshiki; Sachiko Hiraide; Kenji Iizuka; Takeshi Izumi; Taku Yamaguchi attention-deficit/hyperactivity disorder stroke-prone spontaneously hypertensive rats (SHRSP/Ezo) noradrenaline transporter inhibitor medial prefrontal cortex ©...
Journal Article
Spinal cord epidural stimulation for male sexual function in spinal cord injured rats
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Natasha Lorraine Wilkins and others
The Journal of Sexual Medicine, Volume 22, Issue 2, February 2025, Pages 235–249, https://doi.org/10.1093/jsxmed/qdae190
Published: 27 December 2024
... injury (SCI). Methods Male Wistar rats underwent thoracic laminectomies (shams), spinal cord transections, or moderate spinal cord contusion injuries. In urethane-anesthetized rodents, terminal spinal cord epidural stimulation was performed to target the mid-lumbar level spinal generator...
Journal Article
Disrupting heroin-associated memory reconsolidation through actin polymerization inhibition in the nucleus accumbens core
Haiting Zhao and others
International Journal of Neuropsychopharmacology, Volume 28, Issue 1, January 2025, pyae065, https://doi.org/10.1093/ijnp/pyae065
Published: 24 December 2024
... understudied. Methods This study employed a rodent model of self-administered heroin to investigate the involvement of actin polymerization in the reconsolidation of heroin-associated memories. Rats underwent ten days of intravenous heroin self-administration paired with conditioned cues. Subsequently...
Journal Article
Histological Study of the Protective Effect of CoQ10 on Aluminium Chloride-Induced Alzheimer's Disease in Adult Male Albino Rats' Hippocampus
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Salma Osama Abd El-Aziz Ibrahim Shalaan and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.338, https://doi.org/10.1093/qjmed/hcae175.338
Published: 20 November 2024
... radicals. Aim of the Work to detect the protective effect of CoQ10 on aluminium chloride-induced Alzheimer’s disease in albino rats’ hippocampus histologically. Materials and Methods Thirty-six adult male albino rats weighing 200-250 g were divided into four groups. Group I (control group) included...
Journal Article
The Possible Therapeutic Role of MSC Derived Exosomes Extracted from Myocardial Infarction versus Healthy Rat Models in the Heart with Surgically Occluded Right Anterior Coronary Artery in Rats A Histological Study
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Alaa Sabri Farid and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.328, https://doi.org/10.1093/qjmed/hcae175.328
Published: 20 November 2024
... in adult male albino rats. Material and Methods Fifty adult male albino rats weighing 150–250 gm were included with age from 8 to 11 old months in the study. In addition, ten rats weighing 150 gm with age from 7 to 8 old weeks were used for adipose derived exosomes preparation. The rats were divided...
Journal Article
A Histological Study on the Effect of Whey Protein on Liver and Skeletal Muscle with or without Exercise in Adult Male Albino Rats
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Gehan Ahmed Hamed and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.332, https://doi.org/10.1093/qjmed/hcae175.332
Published: 20 November 2024
... to evaluate the effect of whey protein with/or without exercise on the histological structure of the liver and skeletal muscle in adult male albino rats. Materials and Methods Twenty adult male albino rats with weight ranged from 150 to 200 grams were used in this study, rats were randomly divided...
Journal Article
Evaluation of the potential therapeutic efficacy of Lactobacillus rhamnosus in ratsexperimentally infected with Blastocystis hominis
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Sara F Alkady and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.710, https://doi.org/10.1093/qjmed/hcae175.710
Published: 20 November 2024
... of L. rhamnosus in comparison to MTZ. Twenty-eight Sprague- Dawley rats were divided into four groups (seven rats per group), all infected with Blastocystis, except for the non-infected group 1 (G1). The treatment duration was 7 days for MTZ and 10 days for L. rhamnosus...
Journal Article
The Possible Protective Effect of Chia Seed Oil on Atropine Induced Dry Eye Model in Male Adult Albino Rat: A Histological Study
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Yasmin Tarek Rashad Abd Elaziz and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.339, https://doi.org/10.1093/qjmed/hcae175.339
Published: 20 November 2024
...-inflammatory activity. Aim of the Work assess possible protective effect of chia seed oil on atropine induced dry eye in male adult albino rat. Materials and Methods Forty adult male albino rats were used in this study and were divided in to four groups (10 in each group): Group I (Control group...
Journal Article
Internal radiation dose estimates in organs of Wistar rats exposed to sprayed neutron-activated 31SiO2 microparticles: first results of international multicenter study
Valeriy Stepanenko and others
Journal of Radiation Research, Volume 65, Issue 6, November 2024, Pages 744–751, https://doi.org/10.1093/jrr/rrae063
Published: 10 October 2024
... radioactivity in the early period after the atomic bombing of Hiroshima and Nagasaki. The features of the biological effects of internal irradiation by these radionuclides are a subject of scientific discussions and research. The publication presents data on internal radiation doses in experimental Wistar rats...
Journal Article
Molecular systematics of chinchilla rats and taxonomic assessment of the Abrocoma cinerea species complex
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Francisco J González-Pinilla and others
Journal of Mammalogy, Volume 105, Issue 6, December 2024, Pages 1446–1457, https://doi.org/10.1093/jmammal/gyae095
Published: 03 October 2024
... the thinning to 100 and the burn-in of initial samples to 0.25 (25%). The convergence of bPTP analyses was checked visually in the trace plot, and ML and Bayesian solutions were considered. Abstract Chinchilla rats (family Abrocomidae) are hystricomorph rodents primarily inhabiting the central Andes in South...
Journal Article
Assessment of the toxic influence of locally formulated pesticides on hepatic and renal biomarkers in male Wistar rats
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Esther Itunuoluwa Adeyele and others
Toxicology Research, Volume 13, Issue 5, October 2024, tfae157, https://doi.org/10.1093/toxres/tfae157
Published: 30 September 2024
... formulated pesticides in rural area of Nigeria. This study was designed to assessed the effects of the individual chemical compound and their combination on the kidney and liver of rats’ model. Methodology Fifty-four rats divided into six groups and three sub-groups were exposed to 25, 50 and 75% dose...
Journal Article
Effects of Parecoxib Sodium on Early Cognitive Impairment and Inflammation Levels in Burned Rats
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Guangjun Hu and others
Journal of Burn Care & Research, Volume 46, Issue 1, January/February 2025, Pages 67–74, https://doi.org/10.1093/jbcr/irae160
Published: 20 August 2024
... for 10 days. At 2 h, 1 d, 5 d, and 10 d postsurgery, 3 rats from each group were sacrificed. Abdominal aortic blood was collected, and the supernatant was stored at −20 °C for further analysis. ELISA was used to measure the expression levels of inflammatory factors (IL-2, IL-6, TNF-α, and IFN-γ...
Journal Article
Treating Scars After Burns With Pulsed Electric Fields in the Rat Model
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Din Mann and others
Journal of Burn Care & Research, Volume 45, Issue 6, November/December 2024, Pages 1553–1565, https://doi.org/10.1093/jbcr/irae154
Published: 07 August 2024
... Reducing scar size after severe burn injuries is an important and challenging medical, technological, and social problem. We have developed a battery-powered pulsed electric field (PEF) device and surface needle electrode applicator to deliver PEFs to the healing dorsal burn wound in rats. The pulsed...
Journal Article
Robotic-assisted thoracic surgery training in France: a nation-wide survey from young surgeons
Hugo Clermidy and others
Interdisciplinary CardioVascular and Thoracic Surgery, Volume 39, Issue 1, July 2024, ivae115, https://doi.org/10.1093/icvts/ivae115
Published: 18 June 2024
.../licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract OBJECTIVES Evaluate theoretical and practical training of thoracic surgeons-in-training in robotic-assisted thoracic surgery (RATS) in France...
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