Volume 1, Issue 4, September 2022

Brief Report

Nanoscale shape-dependent histone modifications

Wei Zhang and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac172, https://doi.org/10.1093/pnasnexus/pgac172

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Social media sharing of low-quality news sources by political elites

Jana Lasser and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac186, https://doi.org/10.1093/pnasnexus/pgac186

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Estimating R₀ from early exponential growth: parallels between 1918 influenza and 2020 SARS-CoV-2 pandemics

Grant Foster and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac194, https://doi.org/10.1093/pnasnexus/pgac194

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Frequent occurrence of mutations in nsp3 and nsp4 of SARS-CoV-2, presumably caused by the inhaled asthma drug ciclesonide

Akihiro Doi and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac197, https://doi.org/10.1093/pnasnexus/pgac197

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Biological, Health, and Medical Sciences

Administration Of Health Services, Education, and Research

Nature-inspired delivery of mitochondria-targeted angiotensin receptor blocker

Jude M Phillip and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac147, https://doi.org/10.1093/pnasnexus/pgac147

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Allied Health Professions

Correction of large jawbone defect in the mouse using immature osteoblast–like cells and a 3D polylactic acid scaffold

Shigeto Suzuki and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac151, https://doi.org/10.1093/pnasnexus/pgac151

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Return to performance following severe ankle, knee, and hip injuries in National Basketball Association players

Garrett S Bullock and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac176, https://doi.org/10.1093/pnasnexus/pgac176

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Anesthesiology

An electroencephalogram biomarker of fentanyl drug effects

Gustavo A Balanza and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac158, https://doi.org/10.1093/pnasnexus/pgac158

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Anthropology

Ancient dental calculus preserves signatures of biofilm succession and interindividual variation independent of dental pathology

Irina M Velsko and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac148, https://doi.org/10.1093/pnasnexus/pgac148

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Problem-solving in groups of common marmosets (Callithrix jacchus): more than the sum of its parts

Sandro Sehner and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac168, https://doi.org/10.1093/pnasnexus/pgac168

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Applied Biological Sciences

Mosquito tagging using DNA-barcoded nanoporous protein microcrystals

Julius D Stuart and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac190, https://doi.org/10.1093/pnasnexus/pgac190

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Human EWS-FLI protein recapitulates in Drosophila the neomorphic functions that induce Ewing sarcoma tumorigenesis

Cristina Molnar and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac222, https://doi.org/10.1093/pnasnexus/pgac222

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Biochemistry

Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly

Seda Kocaman and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac118, https://doi.org/10.1093/pnasnexus/pgac118

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A highly conserved gene locus in endofungal bacteria codes for the biosynthesis of symbiosis-specific cyclopeptides

Sarah P Niehs and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac152, https://doi.org/10.1093/pnasnexus/pgac152

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Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography

Allison Maker and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac163, https://doi.org/10.1093/pnasnexus/pgac163

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Structural basis for p53 binding to its nucleosomal target DNA sequence

Masahiro Nishimura and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac177, https://doi.org/10.1093/pnasnexus/pgac177

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An explanation of how mutant and wild-type mitochondria might stably co-exist in inherited mitochondrial diseases

Axel Kowald and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac192, https://doi.org/10.1093/pnasnexus/pgac192

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Functional metabolite reserves and lipid homeostasis revealed by the MA-10 Leydig cell metabolome

Prasanthi P Koganti and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac215, https://doi.org/10.1093/pnasnexus/pgac215

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Biophysics and Computational Biology

Immunity-induced criticality of the genotype network of influenza A (H3N2) hemagglutinin

Blake J M Williams and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac143, https://doi.org/10.1093/pnasnexus/pgac143

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High-fidelity control of spin ensemble dynamics via artificial intelligence: from quantum computing to NMR spectroscopy and imaging

Manu Veliparambil Subrahmanian and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac133, https://doi.org/10.1093/pnasnexus/pgac133

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Extracellular vesicle fusion visualized by cryo-electron microscopy

Mattia I Morandi and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac156, https://doi.org/10.1093/pnasnexus/pgac156

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Disease mutations of human α3 Na⁺/K⁺-ATPase define extracellular Na⁺ binding/occlusion kinetics at ion binding site III

Cristina Moreno and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac205, https://doi.org/10.1093/pnasnexus/pgac205

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Biostatistics

SECANT: a biology-guided semi-supervised method for clustering, classification, and annotation of single-cell multi-omics

Xinjun Wang and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac165, https://doi.org/10.1093/pnasnexus/pgac165

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Cell Biology

Vascular endothelial growth factor from retinal pigment epithelium is essential in choriocapillaris and axial length maintenance

Yan Zhang and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac166, https://doi.org/10.1093/pnasnexus/pgac166

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Cryo-electron tomography with mixed-scale dense neural networks reveals key steps in deployment of Toxoplasma invasion machinery

Li-av Segev-Zarko and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac183, https://doi.org/10.1093/pnasnexus/pgac183

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Developmental Biology

Contribution of the Wolffian duct mesenchyme to the formation of the female reproductive tract

Fei Zhao and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac182, https://doi.org/10.1093/pnasnexus/pgac182

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Ecology

Cryocampsis: a biophysical freeze-bending response of shrubs and trees under snow loads

Peter M Ray and M Syndonia Bret-Harte

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac131, https://doi.org/10.1093/pnasnexus/pgac131

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Tracking the upstream history of aquatic microbes in a boreal lake yields new insights on microbial community assembly

Sophie Crevecoeur and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac171, https://doi.org/10.1093/pnasnexus/pgac171

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The stochastic world of emerging viruses

Laurent Gavotte and Roger Frutos

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac185, https://doi.org/10.1093/pnasnexus/pgac185

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Environmental Sciences

Deposit-feeding worms control subsurface ecosystem functioning in intertidal sediment with strong physical forcing

Longhui Deng and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac146, https://doi.org/10.1093/pnasnexus/pgac146

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Magnetic fields produced by subsea high-voltage direct current cables reduce swimming activity of haddock larvae (Melanogrammus aeglefinus)

Alessandro Cresci and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac175, https://doi.org/10.1093/pnasnexus/pgac175

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Evolution

Evolutionary instability of selfish learning in repeated games

Alex McAvoy and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac141, https://doi.org/10.1093/pnasnexus/pgac141

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Phylogenomics shows unique traits in Noctilucales are derived rather than ancestral

Elizabeth C Cooney and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac202, https://doi.org/10.1093/pnasnexus/pgac202

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Immunology and Inflammation

A filarial parasite-encoded human IL-10 receptor antagonist reveals a novel strategy to modulate host responses

Alessandra Ricciardi and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac184, https://doi.org/10.1093/pnasnexus/pgac184

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Socioeconomic disadvantage, chronic stress, and proinflammatory phenotype: an integrative data analysis across the lifecourse

Phoebe H Lam and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac219, https://doi.org/10.1093/pnasnexus/pgac219

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Medical Sciences

High-fidelity reprogramming into Leydig-like cells by CRISPR activation and paracrine factors

Zhaohui Li and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac179, https://doi.org/10.1093/pnasnexus/pgac179

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Microbiology

The Bacillus anthracis S-layer is an exoskeleton-like structure that imparts mechanical and osmotic stabilization to the cell wall

Antonella Fioravanti and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac121, https://doi.org/10.1093/pnasnexus/pgac121

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The role of cell-envelope synthesis for envelope growth and cytoplasmic density in Bacillus subtilis

Yuki Kitahara and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac134, https://doi.org/10.1093/pnasnexus/pgac134

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C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus

Laura Paulowski and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac130, https://doi.org/10.1093/pnasnexus/pgac130

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Wolbachia wAlbB remains stable in Aedes aegypti over 15 years but exhibits genetic background-dependent variation in virus blocking

Xiao Liang and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac203, https://doi.org/10.1093/pnasnexus/pgac203

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Neurology

Label-free hyperspectral imaging and deep-learning prediction of retinal amyloid β-protein and phosphorylated tau

Xiaoxi Du and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac164, https://doi.org/10.1093/pnasnexus/pgac164

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Neuroscience

Axonal architecture of the mouse inner retina revealed by second harmonic generation

Arafat Meah and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac160, https://doi.org/10.1093/pnasnexus/pgac160

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Fast and slow light-induced changes in murine outer retina optical coherence tomography: complementary high spatial resolution functional biomarkers

Shasha Gao and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac208, https://doi.org/10.1093/pnasnexus/pgac208

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Associations between abstract working memory abilities and brain activity underlying long-term recognition of auditory sequences

Gemma Fernández-Rubio and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac216, https://doi.org/10.1093/pnasnexus/pgac216

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Obstetrics and Gynecology

Myometrial progesterone receptor determines a transcription program for uterine remodeling and contractions during pregnancy

San-Pin Wu and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac155, https://doi.org/10.1093/pnasnexus/pgac155

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Ophthalmology

Second hit impels oncogenesis of retinoblastoma in patient-induced pluripotent stem cell-derived retinal organoids: direct evidence for Knudson's theory

Yan-Ping Li and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac162, https://doi.org/10.1093/pnasnexus/pgac162

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Pharmacology

Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice

Stephen Chang and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac191, https://doi.org/10.1093/pnasnexus/pgac191

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Physiology

Skeletal muscle releases extracellular vesicles with distinct protein and microRNA signatures that function in the muscle microenvironment

Sho Watanabe and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac173, https://doi.org/10.1093/pnasnexus/pgac173

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Psychological and Cognitive Sciences

Unperceived motor actions of the balance system interfere with the causal attribution of self-motion

Romain Tisserand and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac174, https://doi.org/10.1093/pnasnexus/pgac174

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Public Health and Epidemiology

Containing novel SARS-CoV-2 variants at source is possible with high-intensity sequencing

Tobias S Brett and Pejman Rohani

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac159, https://doi.org/10.1093/pnasnexus/pgac159

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Subtyping of major SARS-CoV-2 variants reveals different transmission dynamics based on 10 million genomes

Hsin-Chou Yang and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac181, https://doi.org/10.1093/pnasnexus/pgac181

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R_H: a genetic metric for measuring intrahost Plasmodium falciparum relatedness and distinguishing cotransmission from superinfection

Wesley Wong and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac187, https://doi.org/10.1093/pnasnexus/pgac187

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Physical Sciences and Engineering

Applied Mathematics

On the parameter combinations that matter and on those that do not: data-driven studies of parameter (non)identifiability

Nikolaos Evangelou and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac154, https://doi.org/10.1093/pnasnexus/pgac154

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Applied Physical Sciences

Vibrational and electrochemical studies of pectin—a candidate towards environmental friendly lithium-ion battery development

Phillip M Wu and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac127, https://doi.org/10.1093/pnasnexus/pgac127

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Plasmonic gadolinium oxide nanomatryoshkas: bifunctional magnetic resonance imaging enhancers for photothermal cancer therapy

Luke Henderson and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac140, https://doi.org/10.1093/pnasnexus/pgac140

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Fluctuations in pedestrian dynamics routing choices

Alessandro Gabbana and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac169, https://doi.org/10.1093/pnasnexus/pgac169

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Macroscopic properties of buyer–seller networks in online marketplaces

Alberto Bracci and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac201, https://doi.org/10.1093/pnasnexus/pgac201

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Liquid–liquid phase transition in deeply supercooled Stillinger–Weber silicon

Yagyik Goswami and Srikanth Sastry

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac204, https://doi.org/10.1093/pnasnexus/pgac204

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Bioengineering

Sustained degradation of hyaluronic acid using an in situ forming implant

Kelsey Hopkins and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac193, https://doi.org/10.1093/pnasnexus/pgac193

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Biophysics and Computational Biology

Mass-selective and ice-free electron cryomicroscopy protein sample preparation via native electrospray ion-beam deposition

Tim K Esser and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac153, https://doi.org/10.1093/pnasnexus/pgac153

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Computer Sciences

AlphaDrug: protein target specific de novo molecular generation

Hao Qian and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac227, https://doi.org/10.1093/pnasnexus/pgac227

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Earth Resources Engineering

Significant fluctuation in the global sulfate reservoir and oceanic redox state during the Late Devonian event

Chunfang Cai and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac122, https://doi.org/10.1093/pnasnexus/pgac122

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Earth, Atmospheric, and Planetary Sciences

Sulfur-isotope anomalies recorded in Antarctic ice cores as a potential proxy for tracing past ozone layer depletion events

Sanjeev Dasari and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac170, https://doi.org/10.1093/pnasnexus/pgac170

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Mechanical Engineering

A shrinkage-based criterion for evaluating resistance spot weldability of alloyed steels

Shuoshuo Li and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac161, https://doi.org/10.1093/pnasnexus/pgac161

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Cavitation in a soft porous material

Yu Leng and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac150, https://doi.org/10.1093/pnasnexus/pgac150

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Interfacial cavitation

Thomas Henzel and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac217, https://doi.org/10.1093/pnasnexus/pgac217

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Physics

Connecting intercity mobility with urban welfare

Sayat Mimar and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac178, https://doi.org/10.1093/pnasnexus/pgac178

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Social and Political Sciences

Demography

Do introductory courses disproportionately drive minoritized students out of STEM pathways?

Neil Hatfield and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac167, https://doi.org/10.1093/pnasnexus/pgac167

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Economic Sciences

Measuring racial and ethnic disparities in traffic enforcement with large-scale telematics data

William Cai and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac144, https://doi.org/10.1093/pnasnexus/pgac144

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Choices behind the veil of ignorance in Formosan macaques

Yi-Ta Lu and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac188, https://doi.org/10.1093/pnasnexus/pgac188

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Environmental Sciences

Inequality in the availability of residential air conditioning across 115 US metropolitan areas

Yasmin Romitti and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac210, https://doi.org/10.1093/pnasnexus/pgac210

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Political Sciences

Building mass support for global pandemic recovery efforts in the United States

Gautam Nair and Kyle Peyton

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac123, https://doi.org/10.1093/pnasnexus/pgac123

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Psychological and Cognitive Sciences

Gender and ethnicity bias in medicine: a text analysis of 1.8 million critical care records

David M Markowitz

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac157, https://doi.org/10.1093/pnasnexus/pgac157

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Structural measures of personal networks predict migrants’ cultural backgrounds: an explanation from Grid/Group theory

José Luis Molina and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac195, https://doi.org/10.1093/pnasnexus/pgac195

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The salience of choice reduces social responsibility: evidence from lab experiments and compliance with COVID-19 stay-at-home orders

Yan Wang and Krishna Savani

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac200, https://doi.org/10.1093/pnasnexus/pgac200

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Social media behavior is associated with vaccine hesitancy

Steve Rathje and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac207, https://doi.org/10.1093/pnasnexus/pgac207

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Review Articles

A forgotten element of the blue economy: marine biomimetics and inspiration from the deep sea

Robert Blasiak and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac196, https://doi.org/10.1093/pnasnexus/pgac196

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Long-term and short-term preservation strategies for tissue engineering and regenerative medicine products: state of the art and emerging trends

Sara Freitas-Ribeiro and others

PNAS Nexus, Volume 1, Issue 4, September 2022, pgac212, https://doi.org/10.1093/pnasnexus/pgac212

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