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Journal Article

CDRxAbs: antibody small-molecule conjugates with computationally designed target-binding synergy Get access

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Jingzhou Wang and others
Protein Engineering, Design and Selection, Volume 38, 2025, gzaf004, https://doi.org/10.1093/protein/gzaf004
Published: 21 March 2025
Includes: Multimedia
Journal Article

Tuning ProteinMPNN to reduce protein visibility via MHC Class I through direct preference optimization

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Hans-Christof Gasser and others
Protein Engineering, Design and Selection, Volume 38, 2025, gzaf003, https://doi.org/10.1093/protein/gzaf003
Published: 18 March 2025
Journal Article

Enhancing the Thermostability and solubility of a single-domain catalytic antibody Get access

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Yunhang Cui and others
Protein Engineering, Design and Selection, Volume 38, 2025, gzaf002, https://doi.org/10.1093/protein/gzaf002
Published: 17 February 2025
Journal Article

Engineering of a lysosomal-targeted GAA enzyme Get access

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Nicholas Marze and others
Protein Engineering, Design and Selection, Volume 38, 2025, gzaf001, https://doi.org/10.1093/protein/gzaf001
Published: 23 January 2025
Journal Article

Supercharged Phosphotriesterase for improved Paraoxon activity

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Jacob Kronenberg and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae015, https://doi.org/10.1093/protein/gzae015
Published: 18 September 2024
Journal Article

Engineered FHA domains can bind to a variety of Phosphothreonine-containing peptides

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Srinivas S Thota and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae014, https://doi.org/10.1093/protein/gzae014
Published: 14 September 2024
Journal Article

An engineered NKp46 antibody for construction of multi-specific NK cell engagers

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Robert B Lee and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae013, https://doi.org/10.1093/protein/gzae013
Published: 20 August 2024
Journal Article

High titer expression of antibodies using linear expression cassettes for early-stage functional screening Get access

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Shuang Wu and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae012, https://doi.org/10.1093/protein/gzae012
Published: 14 August 2024
Journal Article

Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization

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Gregory H Nielsen and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae010, https://doi.org/10.1093/protein/gzae010
Published: 05 June 2024
Journal Article

DexDesign: an OSPREY-based algorithm for designing de novo D-peptide inhibitors

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Nathan Guerin and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae007, https://doi.org/10.1093/protein/gzae007
Published: 17 May 2024
Journal Article

Improving plastic degrading enzymes via directed evolution

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Yvonne Joho and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae009, https://doi.org/10.1093/protein/gzae009
Published: 07 May 2024
Journal Article

Modular and integrative activity reporters enhance biochemical studies in the yeast ER

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Samantha G Martinusen and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae008, https://doi.org/10.1093/protein/gzae008
Published: 02 May 2024
Journal Article

Sequence-activity mapping via depletion reveals striking mutational tolerance and elucidates functional motifs in Tur1a antimicrobial peptide

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Jonathan Collins and Benjamin J Hackel
Protein Engineering, Design and Selection, Volume 37, 2024, gzae006, https://doi.org/10.1093/protein/gzae006
Published: 14 March 2024
Journal Article

Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids

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Nandan Haloi and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae003, https://doi.org/10.1093/protein/gzae003
Published: 01 February 2024
Journal Article

TIMED-Design: flexible and accessible protein sequence design with convolutional neural networks

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Leonardo V Castorina and others
Protein Engineering, Design and Selection, Volume 37, 2024, gzae002, https://doi.org/10.1093/protein/gzae002
Published: 30 January 2024
Journal Article

De novo design of a polycarbonate hydrolase Get access

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Laura H Holst and others
Protein Engineering, Design and Selection, Volume 36, 2023, gzad022, https://doi.org/10.1093/protein/gzad022
Published: 30 November 2023
Journal Article

abYpap: improvements to the prediction of antibody VH/VL packing using gradient boosted regression

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Veronica A Boron and Andrew C R Martin
Protein Engineering, Design and Selection, Volume 36, 2023, gzad021, https://doi.org/10.1093/protein/gzad021
Published: 28 November 2023
Journal Article

Engineering of a phosphotriesterase with improved stability and enhanced activity for detoxification of the pesticide metabolite malaoxon Get access

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Laura Job and others
Protein Engineering, Design and Selection, Volume 36, 2023, gzad020, https://doi.org/10.1093/protein/gzad020
Published: 06 November 2023
Journal Article

A protein engineering approach toward understanding FKBP51 conformational dynamics and mechanisms of ligand binding Get access

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Jorge A Lerma Romero and others
Protein Engineering, Design and Selection, Volume 36, 2023, gzad014, https://doi.org/10.1093/protein/gzad014
Published: 30 October 2023
Journal Article

The variable conversion of neutralizing anti-SARS-CoV-2 single-chain antibodies to IgG provides insight into RBD epitope accessibility

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Matthew R Chang and others
Protein Engineering, Design and Selection, Volume 36, 2023, gzad008, https://doi.org/10.1093/protein/gzad008
Published: 17 September 2023