Volume 1, Issue 1, Spring 2014
Editorial
A Welcome to Open Forum Infectious Diseases (OFID)
Major Article
Severe Morbidity and Mortality Risk From Malaria in the United States, 1985–2011
Impact of Xpert MTB/RIF on Antiretroviral Therapy-Associated Tuberculosis and Mortality: A Pragmatic Randomized Controlled Trial
Urinalysis in Acute Care of Adults: Pitfalls in Testing and Interpreting Results
Antiretroviral Therapy (ART) Use, Human Immunodeficiency Virus (HIV)-1 RNA Suppression, and Medical Causes of Hospitalization Among HIV-Infected Intravenous Drug Users in the Late ART Era
HIV-infected intravenous drug users are admitted to hospital mainly for non-HIV related illnesses in the late ART era. However , current ART use at admission is low and determines hospital discharge diagnoses.
A Study of Viral Hepatitis E Infection in a Tertiary Care Hospital in Mysore, South India
High Rates of Virological Suppression in a Cohort of Human Immunodeficiency Virus-Positive Adults Receiving Antiretroviral Therapy in Ethiopian Health Centers Irrespective of Concomitant Tuberculosis
Rates of virological suppression after 6 months of ART were high in a cohort of 678 HIV-positive adults managed in Ethiopian health centers, with no significant difference with regard to concomitant tuberculosis at baseline (TB 135; non-TB 543).
Influenza Hospitalizations Among American Indian/Alaska Native People and in the United States General Population
American Indian/Alaska Native (AI/AN) people appear to be at increased risk for hospitalization from influenza illness compared with the general US population. Our results should inform policymakers on seasonal epidemic and pandemic influenza preparedness and response.
Corticosteroid Effects on Sputum Culture in Pulmonary Tuberculosis: A Meta-Regression Analysis
Endothelial Activation and Repair During Hantavirus Infection: Association with Disease Outcome
Higher Human T-Lymphotropic Virus Type 1 Subtype C Proviral Loads Are Associated With Bronchiectasis in Indigenous Australians: Results of a Case-Control Study
In this case-control study, HTLV-1 infection increased risk of bronchiectasis 1.84 times. HTLV-1 proviral loads for bronchiectasis patients were significantly higher than those of controls. HTLV-1 proviral loads correlated with the extent of radiologically determined pulmonary injury.
Candida Pneumonia in Intensive Care Unit?
Rates of Pneumococcal Disease in Adults With Chronic Medical Conditions
Multisite Laboratory Evaluation of a Dual Human Immunodeficiency Virus (HIV)/Syphilis Point-of-Care Rapid Test for Simultaneous Detection of HIV and Syphilis Infection
Factors Associated With Cancer Incidence and With All-Cause Mortality After Cancer Diagnosis Among Human Immunodeficiency Virus-Infected Persons During the Combination Antiretroviral Therapy Era
Bacteremia with Aerococcus sanguinicola: Case Series with Characterization of Virulence Properties
We describe the clinical presentation of eleven cases with Aerococcus sanguinicola bacteremia. All patients were elderly men and a majority of them had urinary tract abnormalities. All isolates formed biofilm and a majority induced platelet aggregation – two potential virulence mechanisms.
Genome-Wide Association Study of Human Immunodeficiency Virus (HIV)-1 Coreceptor Usage in Treatment-Naive Patients from An AIDS Clinical Trials Group Study
Phenotypic determination of HIV-1 coreceptor usage was performed on 593 pre-treatment plasma HIV-1 samples from treatment-naive participants in ACTG A5095. No human genetic variants were significantly associated with virus able to use CXCR4 for entry at the genome-wide level.
Impact of Human Immunodeficiency Virus on the Severity of Buruli Ulcer Disease: Results of a Retrospective Study in Cameroon
The impact of human immunodeficiency virus (HIV) infection on Buruli ulcer (BU) severity and prevalence remains unclear. This study shows that patients who are HIV positive are at risk for BU. Notably, HIV-induced immunosuppression seems to have an impact on BU clinical presentation and disease evolution.
Relationship Between Hepatitis C Clinical Testing Site and Linkage to Care
When compared to those diagnosed in the outpatient, patients with reactive HCV testing in the Emergency Department or in the inpatient setting were less likely to link to care as measured by HCV RNA testing.