MO914
INTRADIALYTIC RESISTANCE TRAINING HAS POSITIVE EFFECT ON SURVIVAL IN HEMODIALYSIS PATIENTS INDEPENDENTLY OF THEIR NUTRITION STATUS MEASURED BY BODY COMPOSITION MONITORING

Malnutrition is considered to be an independent predictor of mortality in hemodialysis population. Physical inactivity is also connected to worse outcomes, and patients are recommended to comply with at least some physical excercise.

The aim of this study was to evaluate the survival of hemodialysed patients, taking into account the nutritional status, assessed by Body Composition Monitor. In addition, analysed the impact of three months intradialytic resistatance training.

It was a prospective study of patients undergoing hemodialysis from three hemodialysis departments. Patients from two departments underwent three months intradialytic resistance training while those from the third department served as controls. Cox multivariate regression analysis was used to analyse patient survival depending on performing intradialytic resistance training and their nutritional status.

The group of 90 patients included 35 women, 55 men (61%) with a mean age of 62.6 years, and a mean dialysis program duration of 49.1 months. 31 patients completed whole three months interdialytic training. In total, 80% of participants survived the follow-up period of two years. Cox regression analysis showed a statistically significant effect of the intervention: the patients who had been training had a benefit in survival (HR 4.4; 95%CI 1.003;19.267; p=0,05). The stratification by nutritional status did not change this model, it was always crucial whether patients exercised or not. Malnourished patients had also a better survival when they were training.

Malnourished hemodialysed patients have higher mortality compared to well-nourished patients. Intradialytic resistance training brings survival benefit and might reduce the adverse effects of malnutrition. Therefore we recommend this intervention even in malnourished hemodialysed patients.